Conserved epitopes dominate cross-CD8+T-cell responses against influenza A H1N1 virus among Asian populations

High Levels of Virus-Specific CD4+T Cells Predict Severe Pandemic Influenza A Virus Infection

(2012) Yan Zhao et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cross-reactive responses to modified M158-66peptides by CD8+T cells that use noncanonical BV genes can describe unknown repertoires

(2012) Galina V. Petrova et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Predominance of heterosubtypic IFN-γ-only-secreting effector memory T cells in pandemic H1N1 naive adults

(2012) Saranya Sridhar et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The design and proof of concept for a CD8+ T cell-based vaccine inducing cross-subtype protection against influenza A virus

(2012) Amabel C L Tan et al.   IMMUNOLOGY AND CELL BIOLOGY

Memory CD4+ T cells protect against influenza through multiple synergizing mechanisms

(2012) K. Kai McKinstry et al.   JOURNAL OF CLINICAL INVESTIGATION

A Human CD4+ T Cell Epitope in the Influenza Hemagglutinin Is Cross-Reactive to Influenza A Virus Subtypes and to Influenza B Virus

(2012) J. A. B. Babon et al.   JOURNAL OF VIROLOGY

Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals

(2012) J. Liu et al.   JOURNAL OF VIROLOGY

Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study

(2012) Fatimah S Dawood et al.   LANCET INFECTIOUS DISEASES

Unbiased identification of target antigens of CD8+ T cells with combinatorial libraries coding for short peptides

(2012) Katherina Siewert et al.   NATURE MEDICINE

Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans

(2012) Tom M Wilkinson et al.   NATURE MEDICINE

CD8 T Cell Epitope Distribution in Viruses Reveals Patterns of Protein Biosynthesis

(2012) Carmen M. Diez-Rivero et al.   PLoS One

Multiple Distinct Forms of CD8+ T Cell Cross-Reactivity and Specificities Revealed after 2009 H1N1 Influenza A Virus Infection in Mice

(2012) Hailong Guo et al.   PLoS One

MHC Class I-Presented T Cell Epitopes Identified by Immunoproteomics Analysis Are Targets for a Cross Reactive Influenza-Specific T Cell Response

(2012) James S. Testa et al.   PLoS One

Memory CD4+ T-cell-mediated protection depends on secondary effectors that are distinct from and superior to primary effectors

(2012) T. M. Strutt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potential T cell epitopes within swine-origin triple reassortant influenza A (H3N2) variant virus which emerged in 2011: An immunoinformatics study

(2012) Venkata R. Duvvuri et al.   VACCINE

Influenza viruses and cross-reactivity in healthy adults: Humoral and cellular immunity induced by seasonal 2007/2008 influenza vaccination against vaccine antigens and 2009 A(H1N1) pandemic influenza virus

(2012) Anna M. Iorio et al.   VACCINE

Structural insights into the binding of hepatitis B virus core peptide to HLA-A2 alleles: Towards designing better vaccines

(2011) Jingxian Liu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Division of labor between subsets of lymph node dendritic cells determines the specificity of the CD8+ T-cell recall response to influenza infection

(2011) Jenny E. Suárez-Ramírez et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Revival of the identification of cytotoxic T-lymphocyte epitopes for immunological diagnosis, therapy and vaccine development

(2011) Jun Liu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The memory phase of the CD4 T-cell response to influenza virus infection maintains its diverse antigen specificity

(2011) Katherine A. Richards et al.   IMMUNOLOGY

The Polyclonal CD8 T Cell Response to Influenza M158-66 Generates a Fully Connected Network of Cross-Reactive Clonotypes to Structurally Related Peptides: A Paradigm for Memory Repertoire Coverage of Novel Epitopes or Escape Mutants

(2011) G. V. Petrova et al.   JOURNAL OF IMMUNOLOGY

Affinity Thresholds for Naive CD8+ CTL Activation by Peptides and Engineered Influenza A Viruses

(2011) A. E. Denton et al.   JOURNAL OF IMMUNOLOGY

Naive T Cell Repertoire Skewing in HLA-A2 Individuals by a Specialized Rearrangement Mechanism Results in Public Memory Clonotypes

(2011) M. Yassai et al.   JOURNAL OF IMMUNOLOGY

Hallmarks of CD4 T cell immunity against influenza

(2011) K. K. McKinstry et al.   JOURNAL OF INTERNAL MEDICINE

Characterization of the Human CD8+ T Cell Response following Infection with 2009 Pandemic Influenza H1N1 Virus

(2011) M. L. B. Hillaire et al.   JOURNAL OF VIROLOGY

Cross-Protective Peptide Vaccine against Influenza A Viruses Developed in HLA-A*2402 Human Immunity Model

(2011) Toru Ichihashi et al.   PLoS One

Humoral and Cell-Mediated Immunity to Pandemic H1N1 Influenza in a Canadian Cohort One Year Post-Pandemic: Implications for Vaccination

(2011) Lisa E. Wagar et al.   PLoS One

Systematic identification of immunodominant CD8+ T-cell responses to influenza A virus in HLA-A2 individuals

(2011) C. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Seasonal influenza infection and live vaccine prime for a response to the 2009 pandemic H1N1 vaccine

(2011) G. L. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T cell responses during influenza infection: getting and keeping control

(2011) Taeg S. Kim et al.   TRENDS IN IMMUNOLOGY

Age-related changes in memory and effector T cells responding to influenza A/H3N2 and pandemic A/H1N1 strains in humans

(2011) Xin Zhou et al.   VACCINE

Cross-Reactive T Cells Are Involved in Rapid Clearance of 2009 Pandemic H1N1 Influenza Virus in Nonhuman Primates

(2011) Jason T. Weinfurter et al.   PLoS Pathogens

Cellular immune responses to recurring influenza strains have limited boosting ability and limited cross-reactivity to other strains

(2010) Y. Keynan et al.   CLINICAL MICROBIOLOGY AND INFECTION

Identification of broad binding class I HLA supertype epitopes to provide universal coverage of influenza A virus

(2010) Jeff Alexander et al.   HUMAN IMMUNOLOGY

Influenza Epitope-Specific CD8+ T Cell Avidity, but Not Cytokine Polyfunctionality, Can Be Determined by TCR  Clonotype

(2010) J. M. Moffat et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: CD4 T Cells Generated from Encounter with Seasonal Influenza Viruses and Vaccines Have Broad Protein Specificity and Can Directly Recognize Naturally Generated Epitopes Derived from the Live Pandemic H1N1 Virus

(2010) K. A. Richards et al.   JOURNAL OF IMMUNOLOGY

Cytotoxic T Lymphocytes Established by Seasonal Human Influenza Cross-React against 2009 Pandemic H1N1 Influenza Virus

(2010) W. Tu et al.   JOURNAL OF VIROLOGY

T Cell-Mediated Protection against Lethal 2009 Pandemic H1N1 Influenza Virus Infection in a Mouse Model

(2010) H. Guo et al.   JOURNAL OF VIROLOGY

Cross-reactive CD8+T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses

(2010) Stephanie Gras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effects of preexisting immunity to influenza on responses to influenza vectors in mice

(2010) William A. Langley et al.   VACCINE

Conserved epitopes of influenza A virus inducing protective immunity and their prospects for universal vaccine development

(2010) Zuzana Staneková et al.   Virology Journal

Protective Efficacy of Cross-Reactive CD8+ T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation Threshold

(2010) Sophie A. Valkenburg et al.   PLoS Pathogens

Emergence and pandemic potential of swine-origin H1N1 influenza virus

(2009) Gabriele Neumann et al.   NATURE

Clinical Features of the Initial Cases of 2009 Pandemic Influenza A (H1N1) Virus Infection in China

(2009) Bin Cao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pre-existing immunity against swine-origin H1N1 influenza viruses in the general human population

(2009) J. A. Greenbaum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunoinformatic comparison of T-cell epitopes contained in novel swine-origin influenza A (H1N1) virus with epitopes in 2008–2009 conventional influenza vaccine

(2009) Anne S. De Groot et al.   VACCINE

Cross-Recognition of Avian H5N1 Influenza Virus by Human Cytotoxic T-Lymphocyte Populations Directed to Human Influenza A Virus

(2008) J. H. C. M. Kreijtz et al.   JOURNAL OF VIROLOGY

Immunomic Analysis of the Repertoire of T-Cell Specificities for Influenza A Virus in Humans

(2008) E. Assarsson et al.   JOURNAL OF VIROLOGY