The design and proof of concept for a CD8+ T cell-based vaccine inducing cross-subtype protection against influenza A virus

Intranasal Administration of the TLR2 Agonist Pam2Cys Provides Rapid Protection against Influenza in Mice

(2012) Amabel C. L. Tan et al.   MOLECULAR PHARMACEUTICS

Synergistic TLR2/6 and TLR9 Activation Protects Mice against Lethal Influenza Pneumonia

(2012) Michael J. Tuvim et al.   PLoS One

Synergistic Interactions of TLR2/6 and TLR9 Induce a High Level of Resistance to Lung Infection in Mice

(2011) J. M. Duggan et al.   JOURNAL OF IMMUNOLOGY

Precursor Frequency and Competition Dictate the HLA-A2-Restricted CD8+ T Cell Responses to Influenza A Infection and Vaccination in HLA-A2.1 Transgenic Mice

(2011) A. C. L. Tan et al.   JOURNAL OF IMMUNOLOGY

Annual Vaccination against Influenza Virus Hampers Development of Virus-Specific CD8+ T Cell Immunity in Children

(2011) R. Bodewes et al.   JOURNAL OF VIROLOGY

Vaccination against Seasonal Influenza A/H3N2 Virus Reduces the Induction of Heterosubtypic Immunity against Influenza A/H5N1 Virus Infection in Ferrets

(2011) R. Bodewes et al.   JOURNAL OF VIROLOGY

Infection with Seasonal Influenza Virus Elicits CD4 T Cells Specific for Genetically Conserved Epitopes That Can Be Rapidly Mobilized for Protective Immunity to Pandemic H1N1 Influenza Virus

(2011) S. Alam et al.   JOURNAL OF VIROLOGY

Toll-like receptor pre-stimulation protects mice against lethal infection with highly pathogenic influenza viruses

(2011) Kyoko Shinya et al.   Virology Journal

Decline of influenza-specific CD8+ T cell repertoire in healthy geriatric donors

(2011) Jessica B Lee et al.   Immunity & Ageing

Structural requirement for the agonist activity of the TLR2 ligand Pam2Cys

(2010) Weiguang Zeng et al.   AMINO ACIDS

A lipopeptide based on the M2 and HA proteins of influenza A viruses induces protective antibody

(2010) David Pejoski et al.   IMMUNOLOGY AND CELL BIOLOGY

Cutting Edge: CD4 T Cells Generated from Encounter with Seasonal Influenza Viruses and Vaccines Have Broad Protein Specificity and Can Directly Recognize Naturally Generated Epitopes Derived from the Live Pandemic H1N1 Virus

(2010) K. A. Richards et al.   JOURNAL OF IMMUNOLOGY

Responses against a Subdominant CD8+ T Cell Epitope Protect against Immunopathology Caused by a Dominant Epitope

(2010) T. J. Ruckwardt et al.   JOURNAL OF IMMUNOLOGY

Memory CD4 T Cells Direct Protective Responses to Influenza Virus in the Lungs through Helper-Independent Mechanisms

(2010) J. R. Teijaro et al.   JOURNAL OF VIROLOGY

Memory CD4+ T cells induce innate responses independently of pathogen

(2010) Tara M Strutt et al.   NATURE MEDICINE

Lipopeptide vaccines illustrate the potential role of subtype-crossreactive T cells in the control of highly virulent influenza

(2009) Wy Ching Ng et al.   Influenza and Other Respiratory Viruses

Elimination of Immunodominant Epitopes from Multispecific DNA-Based Vaccines Allows Induction of CD8 T Cells That Have a Striking Antiviral Potential

(2009) P. Riedl et al.   JOURNAL OF IMMUNOLOGY

Universal influenza DNA vaccine encoding conserved CD4+ T cell epitopes protects against lethal viral challenge in HLA-DR transgenic mice

(2009) Jeff Alexander et al.   VACCINE

HLA class I supertypes: a revised and updated classification

(2008) John Sidney et al.   BMC IMMUNOLOGY

Fiber-modified recombinant adenoviral constructs encoding hepatitis C virus proteins induce potent HCV-specific T cell response

(2008) Duangtawan Thammanichanond et al.   CLINICAL IMMUNOLOGY

Cross-Recognition of Avian H5N1 Influenza Virus by Human Cytotoxic T-Lymphocyte Populations Directed to Human Influenza A Virus

(2008) J. H. C. M. Kreijtz et al.   JOURNAL OF VIROLOGY