Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole

Mechanism of the Synergistic Effect of Amiodarone and Fluconazole in Candida albicans

(2010) S. Gamarra et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Protein Dynamics in Drug Combinations: a Linear Superposition of Individual-Drug Responses

(2010) Naama Geva-Zatorsky et al.   CELL

The Antidepressant Sertraline Targets Intracellular Vesiculogenic Membranes in Yeast

(2010) M. M. Rainey et al.   GENETICS

Polymyxin B, in combination with fluconazole, exerts a potent fungicidal effect

(2010) B. Zhai et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action

(2010) Laura Kapitzky et al.   Molecular Systems Biology

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

Azole Drugs Are Imported By Facilitated Diffusion in Candida albicans and Other Pathogenic Fungi

(2010) Bryce E. Mansfield et al.   PLoS Pathogens

Reverse Genetics in Candida albicans Predicts ARF Cycling Is Essential for Drug Resistance and Virulence

(2010) Elias Epp et al.   PLoS Pathogens

Evolutionary divergence in the fungal response to fluconazole revealed by soft clustering

(2010) Dwight Kuo et al.   GENOME BIOLOGY

Echinocandins: The Newest Class of Antifungals

(2009) Allana J Sucher et al.   ANNALS OF PHARMACOTHERAPY

Invasive fungal infections in the paediatric and neonatal population: diagnostics and management issues

(2009) M.C. Arendrup et al.   CLINICAL MICROBIOLOGY AND INFECTION

Efflux-Mediated Antifungal Drug Resistance

(2009) R. D. Cannon et al.   CLINICAL MICROBIOLOGY REVIEWS

Invasive Fungal Infections

(2009) Antonino Gullo   DRUGS

A Putative P-Type ATPase, Apt1, Is Involved in Stress Tolerance and Virulence inCryptococcus neoformans

(2009) Guanggan Hu et al.   EUKARYOTIC CELL

Precise Gene-Dose Alleles for Chemical Genetics

(2009) Z. Yan et al.   GENETICS

Proteomic Analysis Reveals a Synergistic Mechanism of Fluconazole and Berberine against Fluconazole-ResistantCandida albicans: Endogenous ROS Augmentation

(2009) Yi Xu et al.   JOURNAL OF PROTEOME RESEARCH

Algorithmic guided screening of drug combinations of arbitrary size for activity against cancer cells

(2009) R. G. Zinner et al.   MOLECULAR CANCER THERAPEUTICS

Chemogenomic profiling predicts antifungal synergies

(2009) Gregor Jansen et al.   Molecular Systems Biology

Synergistic drug combinations tend to improve therapeutically relevant selectivity

(2009) Joseph Lehár et al.   NATURE BIOTECHNOLOGY

Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease

(2009) Leah E. Cowen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hsp90 Governs Echinocandin Resistance in the Pathogenic Yeast Candida albicans via Calcineurin

(2009) Sheena D. Singh et al.   PLoS Pathogens

Models from experiments: combinatorial drug perturbations of cancer cells

(2008) Sven Nelander et al.   Molecular Systems Biology

Combination chemical genetics

(2008) Joseph Lehár et al.   Nature Chemical Biology

Network pharmacology: the next paradigm in drug discovery

(2008) Andrew L Hopkins   Nature Chemical Biology

Systematic Validation and Atomic Force Microscopy of Non-Covalent Short Oligonucleotide Barcode Microarrays

(2008) Michael A. Cook et al.   PLoS One

The Chemical Genomic Portrait of Yeast: Uncovering a Phenotype for All Genes

(2008) M. E. Hillenmeyer et al.   SCIENCE

Off-Target Effects of Psychoactive Drugs Revealed by Genome-Wide Assays in Yeast

(2008) Elke Ericson et al.   PLoS Genetics