Inflammation of the Hypothalamus Leads to Defective Pancreatic Islet Function

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes

(2010) M. Igoillo-Esteve et al.   DIABETOLOGIA

p53 Up-regulated Modulator of Apoptosis (PUMA) Activation Contributes to Pancreatic β-Cell Apoptosis Induced by Proinflammatory Cytokines and Endoplasmic Reticulum Stress

(2010) Esteban N. Gurzov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ER Stress in Pancreatic   Cells: The Thin Red Line Between Adaptation and Failure

(2010) D. L. Eizirik et al.   Science Signaling

Molecular and Metabolic Evidence for Mitochondrial Defects Associated With  -Cell Dysfunction in a Mouse Model of Type 2 Diabetes

(2009) H. Lu et al.   DIABETES

The beta cell lesion in type 2 diabetes: there has to be a primary functional abnormality

(2009) S. E. Kahn et al.   DIABETOLOGIA

Hypothalamic Actions of Tumor Necrosis Factor α Provide the Thermogenic Core for the Wastage Syndrome in Cachexia

(2009) Ana Paula Arruda et al.   ENDOCRINOLOGY

Hypothalamic inflammation and energy homeostasis: Resolving the paradox

(2009) Joshua P. Thaler et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity

(2009) M. Milanski et al.   JOURNAL OF NEUROSCIENCE

Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

(2008) Xiaoqing Zhang et al.   CELL

Intracerebroventricular injection of citrate inhibits hypothalamic AMPK and modulates feeding behavior and peripheral insulin signaling

(2008) Graziela R Stoppa et al.   JOURNAL OF ENDOCRINOLOGY

Interleukin-10 is a protective factor against diet-induced insulin resistance in liver

(2008) Dennys E. Cintra et al.   JOURNAL OF HEPATOLOGY

Diet-Induced Inflammation of the Hypothalamus in Obesity

(2008) Lício A. Velloso et al.   NEUROIMMUNOMODULATION