标题
Immune Mechanisms and Pathways Targeted in Type 1 Diabetes
作者
关键词
Immune therapy, Clinical trial, Type 1 diabetes, Prevention, Treatment, Autoimmunity
出版物
Current Diabetes Reports
Volume 18, Issue 10, Pages -
出版商
Springer Nature America, Inc
发表日期
2018-08-30
DOI
10.1007/s11892-018-1066-5
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Learning From Past Failures of Oral Insulin Trials
- (2018) Aaron W. Michels et al. DIABETES
- Loss of B-Cell Anergy in Type 1 Diabetes Is Associated With High-Risk HLA and Non-HLA Disease Susceptibility Alleles
- (2018) Mia J. Smith et al. DIABETES
- C-Peptide Decline in Type 1 Diabetes Has Two Phases: An Initial Exponential Fall and a Subsequent Stable Phase
- (2018) Beverley M. Shields et al. DIABETES CARE
- A Type 1 Diabetes Genetic Risk Score Predicts Progression of Islet Autoimmunity and Development of Type 1 Diabetes in Individuals at Risk
- (2018) Maria J. Redondo et al. DIABETES CARE
- Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes
- (2018) et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Methyldopa blocks MHC class II binding to disease-specific antigens in autoimmune diabetes
- (2018) David A. Ostrov et al. JOURNAL OF CLINICAL INVESTIGATION
- Verapamil and beta cell function in adults with recent-onset type 1 diabetes
- (2018) Fernando Ovalle et al. NATURE MEDICINE
- Alpha-1 antitrypsin treatment of new-onset type 1 diabetes: An open-label, phase I clinical trial (RETAIN) to assess safety and pharmacokinetics
- (2018) Gordon C Weir et al. PEDIATRIC DIABETES
- Application of a Genetic Risk Score to Racially Diverse Type 1 Diabetes Populations Demonstrates the Need for Diversity in Risk-Modeling
- (2018) Daniel J. Perry et al. Scientific Reports
- Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children
- (2018) Ezio Bonifacio et al. PLOS MEDICINE
- Frequency and phenotype of type 1 diabetes in the first six decades of life: a cross-sectional, genetically stratified survival analysis from UK Biobank
- (2018) Nicholas J Thomas et al. Lancet Diabetes & Endocrinology
- Glucokinase Gene May Be a More Suitable Target Than the Insulin Gene for Detection of β Cell Death
- (2017) Jana Sklenarova et al. ENDOCRINOLOGY
- Effect of Oral Insulin on Prevention of Diabetes in Relatives of Patients With Type 1 Diabetes
- (2017) et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- NK cell subsets in autoimmune diseases
- (2017) Cai Zhang et al. JOURNAL OF AUTOIMMUNITY
- Single-Cell RNA Sequencing Reveals Expanded Clones of Islet Antigen-Reactive CD4+T Cells in Peripheral Blood of Subjects with Type 1 Diabetes
- (2017) Karen Cerosaletti et al. JOURNAL OF IMMUNOLOGY
- Genetics of type 1 diabetes
- (2017) Maria J Redondo et al. PEDIATRIC DIABETES
- Safety and efficacy of autoantigen-specific therapy with 2 doses of alum-formulated glutamate decarboxylase in children with multiple islet autoantibodies and risk for type 1 diabetes: A randomized clinical trial
- (2017) Helena Elding Larsson et al. PEDIATRIC DIABETES
- Immunological Balance Is Associated with Clinical Outcome after Autologous Hematopoietic Stem Cell Transplantation in Type 1 Diabetes
- (2017) Kelen C. R. Malmegrim et al. Frontiers in Immunology
- Avidity and Bystander Suppressive Capacity of Human Regulatory T Cells Expressing De Novo Autoreactive T-Cell Receptors in Type 1 Diabetes
- (2017) Wen-I Yeh et al. Frontiers in Immunology
- MicroRNAs as stress regulators in pancreatic beta cells and diabetes
- (2017) Mary P. LaPierre et al. Molecular Metabolism
- Expansion of Human Tregs from Cryopreserved Umbilical Cord Blood for GMP-Compliant Autologous Adoptive Cell Transfer Therapy
- (2017) Howard R. Seay et al. Molecular Therapy-Methods & Clinical Development
- Type 1 Diabetes and Type 1 Interferonopathies: Localization of a Type 1 Common Thread of Virus Infection in the Pancreas
- (2017) Virginie S.E. Jean-Baptiste et al. EBioMedicine
- IL-22-producing CD4+T cells in the treatment response of rheumatoid arthritis to combination therapy with methotrexate and leflunomide
- (2017) Wei Zhong et al. Scientific Reports
- Plasma-derived exosome characterization reveals a distinct microRNA signature in long duration Type 1 diabetes
- (2017) Marta Garcia-Contreras et al. Scientific Reports
- Efficacy, durability, and response predictors of low-dose interleukin-2 therapy for chronic graft-versus-host disease
- (2016) John Koreth et al. BLOOD
- Validation of a rapid type 1 diabetes autoantibody screening assay for community-based screening of organ donors to identify subjects at increased risk for the disease
- (2016) C. Wasserfall et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Antithymocyte Globulin Plus G-CSF Combination Therapy Leads to Sustained Immunomodulatory and Metabolic Effects in a Subset of Responders With Established Type 1 Diabetes
- (2016) Michael J. Haller et al. DIABETES
- Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes
- (2016) Aaron W. Michels et al. DIABETES
- Type 1 Diabetes Genetic Risk Score: A Novel Tool to Discriminate Monogenic and Type 1 Diabetes
- (2016) Kashyap A. Patel et al. DIABETES
- Elevations in the Fasting Serum Proinsulin–to–C-Peptide Ratio Precede the Onset of Type 1 Diabetes
- (2016) Emily K. Sims et al. DIABETES CARE
- Do Electrochemiluminescence Assays Improve Prediction of Time to Type 1 Diabetes in Autoantibody-Positive TrialNet Subjects?
- (2016) Alexandra Fouts et al. DIABETES CARE
- ECL-IAA and ECL-GADA Can Identify High-Risk Single Autoantibody-Positive Relatives in the TrialNet Pathway to Prevention Study
- (2016) Andrea K. Steck et al. Diabetes Technology & Therapeutics
- Antithymocyte globulin therapy for patients with recent-onset type 1 diabetes: 2 year results of a randomised trial
- (2016) Stephen E. Gitelman et al. DIABETOLOGIA
- The quest to make fully functional human pancreatic beta cells from embryonic stem cells: climbing a mountain in the clouds
- (2016) James D. Johnson DIABETOLOGIA
- Interleukin-1 antagonism moderates the inflammatory state associated with Type 1 diabetes during clinical trials conducted at disease onset
- (2016) Susanne M. Cabrera et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The progress and potential of proteomic biomarkers for type 1 diabetes in children
- (2016) Robert Moulder et al. Expert Review of Proteomics
- Foxp3, Regulatory T Cell, and Autoimmune Diseases
- (2016) Jin-Hui Tao et al. INFLAMMATION
- Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor
- (2016) Katherine G. MacDonald et al. JOURNAL OF CLINICAL INVESTIGATION
- A multiplex assay combining insulin, GAD, IA-2 and transglutaminase autoantibodies to facilitate screening for pre-type 1 diabetes and celiac disease
- (2016) Zhiyuan Zhao et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Genetic risk factors for type 1 diabetes
- (2016) Flemming Pociot et al. LANCET
- Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes
- (2016) Jenny Aurielle B Babon et al. NATURE MEDICINE
- Early signs of disease in type 1 diabetes
- (2016) Robert Moulder et al. PEDIATRIC DIABETES
- The DIPP project: 20 years of discovery in type 1 diabetes
- (2016) Michael J Haller et al. PEDIATRIC DIABETES
- Identification of tissue-specific cell death using methylation patterns of circulating DNA
- (2016) Roni Lehmann-Werman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion
- (2016) T. Delong et al. SCIENCE
- Proinsulin and heat shock protein 90 as biomarkers of beta-cell stress in the early period after onset of type 1 diabetes
- (2016) Renecia A. Watkins et al. Translational Research
- Generation of stem cell-derived β-cells from patients with type 1 diabetes
- (2016) Jeffrey R. Millman et al. Nature Communications
- Multipotent mesenchymal stromal cells from patients with newly diagnosed type 1 diabetes mellitus exhibit preserved in vitro and in vivo immunomodulatory properties
- (2016) Juliana Navarro Ueda Yaochite et al. Stem Cell Research & Therapy
- Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study
- (2016) Ulla Uusitalo et al. JAMA Pediatrics
- Circulating Differentially Methylated Amylin DNA as a Biomarker of β-Cell Loss in Type 1 Diabetes
- (2016) John A. Olsen et al. PLoS One
- Prediction of Impending Type 1 Diabetes through Automated Dual-Label Measurement of Proinsulin:C-Peptide Ratio
- (2016) Annelien Van Dalem et al. PLoS One
- Dietary intake of soluble fiber and risk of islet autoimmunity by 5 y of age: results from the TEDDY study
- (2015) Andreas Beyerlein et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Differentiation of human pluripotent stem cells into β-cells: Potential and challenges
- (2015) Nina Quiskamp et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- Tolerance Induction and Reversal of Diabetes in Mice Transplanted with Human Embryonic Stem Cell-Derived Pancreatic Endoderm
- (2015) Gregory L. Szot et al. Cell Stem Cell
- Elevations in Circulating Methylated and Unmethylated Preproinsulin DNA in New-Onset Type 1 Diabetes
- (2015) Marisa M. Fisher et al. DIABETES
- Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes
- (2015) Martha Campbell-Thompson et al. DIABETES
- Staging Presymptomatic Type 1 Diabetes: A Scientific Statement of JDRF, the Endocrine Society, and the American Diabetes Association
- (2015) Richard A. Insel et al. DIABETES CARE
- Predicting Type 1 Diabetes Using Biomarkers
- (2015) Ezio Bonifacio DIABETES CARE
- Predictors of Progression From the Appearance of Islet Autoantibodies to Early Childhood Diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY)
- (2015) Andrea K. Steck et al. DIABETES CARE
- The Effect of DPT-1 Intravenous Insulin Infusion and Daily Subcutaneous Insulin on Endogenous Insulin Secretion and Postprandial Glucose Tolerance
- (2015) Wei Hao et al. DIABETES CARE
- A Type 1 Diabetes Genetic Risk Score Can Aid Discrimination Between Type 1 and Type 2 Diabetes in Young Adults
- (2015) Richard A. Oram et al. DIABETES CARE
- Electrochemiluminescence Assays for Insulin and Glutamic Acid Decarboxylase Autoantibodies Improve Prediction of Type 1 Diabetes Risk
- (2015) Dongmei Miao et al. Diabetes Technology & Therapeutics
- The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study
- (2015) Jeffrey P. Krischer et al. DIABETOLOGIA
- Effects of High-Dose Oral Insulin on Immune Responses in Children at High Risk for Type 1 Diabetes
- (2015) Ezio Bonifacio et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients
- (2015) Michelle Rosenzwajg et al. JOURNAL OF AUTOIMMUNITY
- Immunogenetics of type 1 diabetes: A comprehensive review
- (2015) Janelle A. Noble JOURNAL OF AUTOIMMUNITY
- β Cell death and dysfunction during type 1 diabetes development in at-risk individuals
- (2015) Kevan C. Herold et al. JOURNAL OF CLINICAL INVESTIGATION
- Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients
- (2015) Mark R. Rigby et al. JOURNAL OF CLINICAL INVESTIGATION
- Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers
- (2015) Suna Onengut-Gumuscu et al. NATURE GENETICS
- Organ donor specimens: What can they tell us about type 1 diabetes?
- (2015) Martha Campbell-Thompson PEDIATRIC DIABETES
- Type 1 diabetes immunotherapy using polyclonal regulatory T cells
- (2015) Jeffrey A. Bluestone et al. Science Translational Medicine
- New Insight on Human Type 1 Diabetes Biology: nPOD and nPOD-Transplantation
- (2014) Alberto Pugliese et al. Current Diabetes Reports
- Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in New-Onset Type 1 Diabetes: A Multicenter Analysis
- (2014) F. D'Addio et al. DIABETES
- Proinsulin-Specific, HLA-DQ8, and HLA-DQ8-Transdimer–Restricted CD4+T Cells Infiltrate Islets in Type 1 Diabetes
- (2014) Vimukthi Pathiraja et al. DIABETES
- Reduction in CD4 Central Memory T-Cell Subset in Costimulation Modulator Abatacept-Treated Patients With Recent-Onset Type 1 Diabetes Is Associated With Slower C-Peptide Decline
- (2014) T. Orban et al. DIABETES
- Loss of Anergic B Cells in Prediabetic and New-Onset Type 1 Diabetic Patients
- (2014) Mia J. Smith et al. DIABETES
- Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes
- (2014) Sefina Arif et al. DIABETES
- Preserved β-Cell Function in Type 1 Diabetes by Mesenchymal Stromal Cells
- (2014) Per-Ola Carlsson et al. DIABETES
- Low-Dose Otelixizumab Anti-CD3 Monoclonal Antibody DEFEND-1 Study: Results of the Randomized Phase III Study in Recent-Onset Human Type 1 Diabetes
- (2014) Ronnie Aronson et al. DIABETES CARE
- Early Childhood Gut Microbiomes Show Strong Geographic Differences Among Subjects at High Risk for Type 1 Diabetes: Figure 1
- (2014) Kaisa M. Kemppainen et al. DIABETES CARE
- Feature ranking of type 1 diabetes susceptibility genes improves prediction of type 1 diabetes
- (2014) Christiane Winkler et al. DIABETOLOGIA
- Analysis of β-Cell Death in Type 1 Diabetes by Droplet Digital PCR
- (2014) Sahar Usmani-Brown et al. ENDOCRINOLOGY
- Diabetes-Associated MicroRNAs in Pediatric Patients With Type 1 Diabetes Mellitus: A Cross-Sectional Cohort Study
- (2014) Julia Osipova et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes
- (2014) Michael J. Haller et al. JOURNAL OF CLINICAL INVESTIGATION
- Effect of docosahexaenoic acid supplementation on inflammatory cytokine levels in infants at high genetic risk for type 1 diabetes
- (2014) H Peter Chase et al. PEDIATRIC DIABETES
- C-Abl Inhibitor Imatinib Enhances Insulin Production by β Cells: C-Abl Negatively Regulates Insulin Production via Interfering with the Expression of NKx2.2 and GLUT-2
- (2014) Chang-Qing Xia et al. PLoS One
- Tissue-Specific Methylation of Human Insulin Gene and PCR Assay for Monitoring Beta Cell Death
- (2014) Mohamed I. Husseiny et al. PLoS One
- Combination therapy with sitagliptin and lansoprazole in patients with recent-onset type 1 diabetes (REPAIR-T1D): 12-month results of a multicentre, randomised, placebo-controlled, phase 2 trial
- (2014) Kurt J Griffin et al. Lancet Diabetes & Endocrinology
- A strategy to find gene combinations that identify children who progress rapidly to type 1 diabetes after islet autoantibody seroconversion
- (2013) Ezio Bonifacio et al. ACTA DIABETOLOGICA
- Clinical Grade Manufacturing of Human Alloantigen-Reactive Regulatory T Cells for Use in Transplantation
- (2013) A. L. Putnam et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Immune Therapy and -Cell Death in Type 1 Diabetes
- (2013) J. Lebastchi et al. DIABETES
- Patterns of -Cell Autoantibody Appearance and Genetic Associations During the First Years of Life
- (2013) J. Ilonen et al. DIABETES
- Teplizumab Preserves C-Peptide in Recent-Onset Type 1 Diabetes: Two-Year Results From the Randomized, Placebo-Controlled Protege Trial
- (2013) W. Hagopian et al. DIABETES
- B-Lymphocyte Depletion With Rituximab and -Cell Function: Two-Year Results
- (2013) M. D. Pescovitz et al. DIABETES CARE
- Costimulation Modulation With Abatacept in Patients With Recent-Onset Type 1 Diabetes: Follow-up 1 Year After Cessation of Treatment
- (2013) Tihamer Orban et al. DIABETES CARE
- Efficacy and safety of low-dose otelixizumab anti-CD3 monoclonal antibody in preserving C-peptide secretion in adolescent type 1 diabetes: DEFEND-2, a randomized, placebo-controlled, double-blind, multi-centre study
- (2013) P. Ambery et al. DIABETIC MEDICINE
- The diagnosis of insulitis in human type 1 diabetes
- (2013) M. L. Campbell-Thompson et al. DIABETOLOGIA
- Imatinib mesilate-induced phosphatidylinositol 3-kinase signalling and improved survival in insulin-producing cells: role of Src homology 2-containing inositol 5′-phosphatase interaction with c-Abl
- (2013) D. Mokhtari et al. DIABETOLOGIA
- Subsets of human natural killer cells and their regulatory effects
- (2013) Binqing Fu et al. IMMUNOLOGY
- Seroconversion to Multiple Islet Autoantibodies and Risk of Progression to Diabetes in Children
- (2013) Anette G. Ziegler et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Small-Molecule Inducer of β Cell Proliferation Identified by High-Throughput Screening
- (2013) Weijun Shen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials
- (2013) Antoinette Moran et al. LANCET
- Low-Dose Interleukin-2 Therapy Restores Regulatory T Cell Homeostasis in Patients with Chronic Graft-Versus-Host Disease
- (2013) K.-i. Matsuoka et al. Science Translational Medicine
- The Pathogenesis and Natural History of Type 1 Diabetes
- (2013) M. A. Atkinson Cold Spring Harbor Perspectives in Medicine
- Stem Cell Therapy to Cure Type 1 Diabetes: From Hype to Hope
- (2013) Preeti Chhabra et al. Stem Cells Translational Medicine
- Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial
- (2013) Mark R Rigby et al. Lancet Diabetes & Endocrinology
- Low-dose interleukin 2 in patients with type 1 diabetes: a phase 1/2 randomised, double-blind, placebo-controlled trial
- (2013) Agnès Hartemann et al. Lancet Diabetes & Endocrinology
- Antithymocyte globulin treatment for patients with recent-onset type 1 diabetes: 12-month results of a randomised, placebo-controlled, phase 2 trial
- (2013) Stephen E Gitelman et al. Lancet Diabetes & Endocrinology
- Removal of Bovine Insulin From Cow's Milk Formula and Early Initiation of Beta-Cell Autoimmunity in the FINDIA Pilot Study
- (2012) Outi Vaarala et al. ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE
- Effect of the PTPN22 and INS Risk Genotypes on the Progression to Clinical Type 1 Diabetes After the Initiation of -Cell Autoimmunity
- (2012) J. Lempainen et al. DIABETES
- Rapamycin/IL-2 Combination Therapy in Patients With Type 1 Diabetes Augments Tregs yet Transiently Impairs -Cell Function
- (2012) S. A. Long et al. DIABETES
- Fall in C-Peptide During First 2 Years From Diagnosis: Evidence of at Least Two Distinct Phases From Composite Type 1 Diabetes TrialNet Data
- (2012) C. J. Greenbaum et al. DIABETES
- Signalling danger: endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation
- (2012) D. L. Eizirik et al. DIABETOLOGIA
- Early determinants of type 1 diabetes: experience from the BABYDIAB and BABYDIET studies
- (2011) Sandra Hummel et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Autoreactive Cytotoxic T Lymphocytes Acquire Higher Expression of Cytotoxic Effector Markers in the Islets of NOD Mice after Priming in Pancreatic Lymph Nodes
- (2011) Kate L. Graham et al. AMERICAN JOURNAL OF PATHOLOGY
- Diabetes Antibody Standardization Program: First Proficiency Evaluation of Assays for Autoantibodies to Zinc Transporter 8
- (2011) V. Lampasona et al. CLINICAL CHEMISTRY
- Rituximab Selectively Suppresses Specific Islet Antibodies
- (2011) L. Yu et al. DIABETES
- Loss of Intra-Islet CD20 Expression May Complicate Efficacy of B-Cell–Directed Type 1 Diabetes Therapies
- (2011) David V. Serreze et al. DIABETES
- Evidence That Nasal Insulin Induces Immune Tolerance to Insulin in Adults With Autoimmune Diabetes
- (2011) S. Fourlanos et al. DIABETES
- Impact of Intranasal Insulin on Insulin Antibody Affinity and Isotypes in Young Children With HLA-Conferred Susceptibility to Type 1 Diabetes
- (2011) S. J. Ryhanen et al. DIABETES CARE
- Long-Term Outcome of Individuals Treated With Oral Insulin: Diabetes Prevention Trial-Type 1 (DPT-1) oral insulin trial
- (2011) K. Vehik et al. DIABETES CARE
- Age of Islet Autoantibody Appearance and Mean Levels of Insulin, but Not GAD or IA-2 Autoantibodies, Predict Age of Diagnosis of Type 1 Diabetes: Diabetes Autoimmunity Study in the Young
- (2011) A. K. Steck et al. DIABETES CARE
- Diabetes Antibody Standardization Program: First evaluation of assays for autoantibodies to IA-2
- (2011) M. Schlosser et al. DIABETES CARE
- Primary Dietary Intervention Study to Reduce the Risk of Islet Autoimmunity in Children at Increased Risk for Type 1 Diabetes: The BABYDIET study
- (2011) S. Hummel et al. DIABETES CARE
- Effect of rituximab on human in vivo antibody immune responses
- (2011) Mark D. Pescovitz et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Asthma endotypes: A new approach to classification of disease entities within the asthma syndrome
- (2011) Jan Lötvall et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Teplizumab for treatment of type 1 diabetes (Protégé study): 1-year results from a randomised, placebo-controlled trial
- (2011) Nicole Sherry et al. LANCET
- Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial
- (2011) Tihamer Orban et al. LANCET
- Detection of cell death in diabetes using differentially methylated circulating DNA
- (2011) E. M. Akirav et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CD4+Foxp3+ regulatory T cell therapy in transplantation
- (2011) Q. Tang et al. Journal of Molecular Cell Biology
- Cyclosporin and methotrexate therapy induces remission in type 1 diabetes mellitus
- (2010) Douglas O. Sobel et al. ACTA DIABETOLOGICA
- Independence of exogenous insulin following immunoablation and stem cell reconstitution in newly diagnosed diabetes type I
- (2010) E Snarski et al. BONE MARROW TRANSPLANTATION
- GAD-alum treatment induces GAD65-specific CD4+CD25highFOXP3+ cells in type 1 diabetic patients
- (2010) Maria Hjorth et al. CLINICAL IMMUNOLOGY
- Early induction of GAD65-reactive Th2 response in type 1 diabetic children treated with alum-formulated GAD65
- (2010) Stina Axelsson et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Proinsulin/C-peptide ratio, glucagon and remission in new-onset Type 1 diabetes mellitus in young adults
- (2010) A. Schölin et al. DIABETIC MEDICINE
- Diabetes Antibody Standardization Program: evaluation of assays for insulin autoantibodies
- (2010) M. Schlosser et al. DIABETOLOGIA
- Extended evaluation of the safety and efficacy of GAD treatment of children and adolescents with recent-onset type 1 diabetes: a randomised controlled trial
- (2010) J. Ludvigsson et al. DIABETOLOGIA
- Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass
- (2010) B. Keymeulen et al. DIABETOLOGIA
- The Trial to Reduce IDDM in the Genetically at Risk (TRIGR) study: recruitment, intervention and follow-up
- (2010) H. K. Åkerblom et al. DIABETOLOGIA
- Autologous Hematopoietic Stem Cell Transplantation for Type 1 Diabetes
- (2009) Júlio C. Voltarelli et al. Annals of the New York Academy of Sciences
- First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127− T regulatory cells
- (2009) Piotr Trzonkowski et al. CLINICAL IMMUNOLOGY
- Etanercept Treatment in Children With New-Onset Type 1 Diabetes: Pilot randomized, placebo-controlled, double-blind study
- (2009) L. Mastrandrea et al. DIABETES CARE
- Improved Early Event-Free Survival With Imatinib in Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: A Children's Oncology Group Study
- (2009) Kirk R. Schultz et al. JOURNAL OF CLINICAL ONCOLOGY
- Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
- (2009) Jeffrey C Barrett et al. NATURE GENETICS
- Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function
- (2009) Mark D. Pescovitz et al. NEW ENGLAND JOURNAL OF MEDICINE
- Insulin Gene Expression Is Regulated by DNA Methylation
- (2009) Akio Kuroda et al. PLoS One
- Generation of pluripotent stem cells from patients with type 1 diabetes
- (2009) R. Maehr et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immunomodulation by Mesenchymal Stem Cells: A Potential Therapeutic Strategy for Type 1 Diabetes
- (2008) R. Abdi et al. DIABETES
- HLA DR-DQ Haplotypes and Genotypes and Type 1 Diabetes Risk: Analysis of the Type 1 Diabetes Genetics Consortium Families
- (2008) H. Erlich et al. DIABETES
- Diabetes Antibody Standardization Program: evaluation of assays for autoantibodies to glutamic acid decarboxylase and islet antigen-2
- (2008) C. Törn et al. DIABETOLOGIA
- Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial
- (2008) Kirsti Näntö-Salonen et al. LANCET
- Concordance for Islet Autoimmunity among Monozygotic Twins
- (2008) Maria J. Redondo et al. NEW ENGLAND JOURNAL OF MEDICINE
- GAD Treatment and Insulin Secretion in Recent-Onset Type 1 Diabetes
- (2008) Johnny Ludvigsson et al. NEW ENGLAND JOURNAL OF MEDICINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now