C-Abl Inhibitor Imatinib Enhances Insulin Production by β Cells: C-Abl Negatively Regulates Insulin Production via Interfering with the Expression of NKx2.2 and GLUT-2

Rapid Amelioration of Hyperglycemia Facilitated by Dasatinib in a Chronic Myeloid Leukemia Patient with type 2 Diabetes Mellitus

(2014) Keiko Ono et al.   INTERNAL MEDICINE

Long-Term Follow-Up Outcome of Imatinib Mesylate Treatment for Recurrent and Unresectable Gastrointestinal Stromal Tumors

(2013) Seiko Saito et al.   DIGESTION

One vs Three Years of Adjuvant Imatinib for Operable Gastrointestinal Stromal Tumor

(2012) Heikki Joensuu et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Novel computational analysis of protein binding array data identifies direct targets of Nkx2.2 in the pancreas

(2011) Jonathon T Hill et al.   BMC BIOINFORMATICS

Discovery and Characterization of a Cell-Permeable, Small-Molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site

(2011) Jingsong Yang et al.   CHEMISTRY & BIOLOGY

MafA and MafB activity in pancreatic β cells

(2011) Yan Hang et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

NKX6.1 Promotes PDX-1-Induced Liver to Pancreatic β-Cells Reprogramming

(2010) Shiraz Gefen-Halevi et al.   Cellular Reprogramming

Plasma Adiponectin Levels Are Markedly Elevated in Imatinib-Treated Chronic Myeloid Leukemia (CML) Patients: A Mechanism for Improved Insulin Sensitivity in Type 2 Diabetic CML Patients?

(2010) Stephen Fitter et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Combination of MafA, PDX-1 and NeuroD is a Useful Tool to Efficiently Induce Insulin-Producing Surrogate β -Cells

(2009) Hideaki Kaneto et al.   CURRENT MEDICINAL CHEMISTRY

Cooperative Transcriptional Regulation of the Essential Pancreatic Islet GeneNeuroD1(Beta2) by Nkx2.2 and Neurogenin 3

(2009) Keith R. Anderson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PDX-1 and MafA Play a Crucial Role in Pancreatic β-Cell Differentiation and Maintenance of Mature β-Cell Function

(2008) Hideaki KANETO et al.   ENDOCRINE JOURNAL

PDX-1 functions as a master factor in the pancreas

(2008) Hideaki Kaneto   Frontiers in Bioscience-Landmark

Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice

(2008) C. Louvet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imatinib mesylate improves insulin sensitivity and glucose disposal rates in rats fed a high-fat diet

(2007) Robert Hägerkvist et al.   CLINICAL SCIENCE

Restoration of insulin sensitivity following treatment with imatinib mesylate (Gleevec) in non-diabetic patients with chronic myelogenic leukemia (CML)

(2007) Apostolos Tsapas et al.   LEUKEMIA RESEARCH