All Roads to Schizophrenia Lead to Dopamine Supersensitivity and Elevated Dopamine D2High Receptors

The Effect of Antipsychotics on the High-Affinity State of D2 and D3 Receptors

(2009) Ariel Graff-Guerrero et al.   ARCHIVES OF GENERAL PSYCHIATRY

In Vitro and in Vivo Evidence for a Lack of Interaction with Dopamine D2 Receptors by the Metabotropic Glutamate 2/3 Receptor Agonists 1S,2S,5R,6S-2-Aminobicyclo[3.1.0]hexane-2,6-bicaroxylate Monohydrate (LY354740) and (-)-2-Oxa-4-aminobicyclo[3.1.0] Hexane-4,6-dicarboxylic Acid (LY379268)

(2009) M. J. Fell et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Schizophrenia model of elevated D2High receptors: Haloperidol reverses the amphetamine-induced elevation in dopamine D2High

(2009) Philip Seeman   SCHIZOPHRENIA RESEARCH

Glutamate agonist LY404,039 for treating schizophrenia has affinity for the dopamine D2Highreceptor

(2009) Philip Seeman et al.   SYNAPSE

Ex vivo [11C]-(+)-PHNO binding is unchanged in animal models displaying increased high-affinity states of the D2receptor in vitro

(2009) Patrick N. McCormick et al.   SYNAPSE

Dopamine D2/3receptor occupancy of apomorphine in the nonhuman primate brain-A comparative PET study with [11C]raclopride and [11C]MNPA

(2009) Sjoerd J. Finnema et al.   SYNAPSE

Rats with persistently high exploratory activity have both higher extracellular dopamine levels and higher proportion of D2Highreceptors in the striatum

(2009) Aet Alttoa et al.   SYNAPSE

Increased dopamine D2Highreceptors in rats reared in social isolation

(2009) Madeleine V. King et al.   SYNAPSE

Pharmacological characterization of 2-methoxy-N-propylnorapomorphine's interactions with D2and D3dopamine receptors

(2009) Mette Skinbjerg et al.   SYNAPSE

Repeated administration of a dopamine D1 receptor agonist reverses the increased proportions of striatal dopamine D1Highand D2Highreceptors in methamphetamine-sensitized rats

(2008) Takahide Shuto et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cocaine self-administration produces a persistent increase in dopamine D2High receptors

(2008) Lisa A. Briand et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database

(2008) Nicole C Allen et al.   NATURE GENETICS

The Dopamine D2 Receptors in High-Affinity State and D3 Receptors in Schizophrenia: A Clinical [11C]-(+)-PHNO PET Study

(2008) Ariel Graff-Guerrero et al.   NEUROPSYCHOPHARMACOLOGY

Atypical Antipsychotics: CATIE Study, Drug-Induced Movement Disorder and Resulting Iatrogenic Psychiatric-Like Symptoms, Supersensitivity Rebound Psychosis and Withdrawal Discontinuation Syndromes

(2008) Guy Chouinard et al.   PSYCHOTHERAPY AND PSYCHOSOMATICS

Increase of dopamine D2High receptors in the striatum of rats sensitized to caffeine motor effects

(2008) Nicola Simola et al.   SYNAPSE

Dopamine D2Highreceptors on intact cells

(2008) Philip Seeman   SYNAPSE

Glutamate receptor mGlu2 and mGlu3 knockout striata are dopamine supersensitive, with elevated D2Highreceptors and marked supersensitivity to the dopamine agonist (+)PHNO

(2008) Philip Seeman et al.   SYNAPSE

Dopamine D2Highreceptors measured ex vivo are elevated in amphetamine-sensitized animals

(2008) Philip Seeman   SYNAPSE

Dopamine D2 receptor radiotracers [11C](+)-PHNO and [3H]raclopride are indistinguishably inhibited by D2 agonists and antagonists ex vivo

(2007) Patrick N. McCormick et al.   NUCLEAR MEDICINE AND BIOLOGY