标题
Molecular mechanisms of ageing and related diseases
作者
关键词
-
出版物
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
Volume 41, Issue 7, Pages 445-458
出版商
Wiley
发表日期
2014-05-06
DOI
10.1111/1440-1681.12247
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Tracking and fixed ranking of leukocyte telomere length across the adult life course
- (2013) Athanase Benetos et al. AGING CELL
- Constitutional Mutations in RTEL1 Cause Severe Dyskeratosis Congenita
- (2013) Amanda J. Walne et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Structure of Human Telomeric RNA (TERRA): Stacking of Two G-Quadruplex Blocks in K+ Solution
- (2013) Herry Martadinata et al. BIOCHEMISTRY
- A homozygous telomerase T-motif variant resulting in markedly reduced repeat addition processivity in siblings with Hoyeraal Hreidarsson syndrome
- (2013) M. M. Gramatges et al. BLOOD
- Malignancies and monoclonal gammopathy in Gaucher disease; a systematic review of the literature
- (2013) Maarten Arends et al. BRITISH JOURNAL OF HAEMATOLOGY
- YAP/TEAD-Mediated Transcription Controls Cellular Senescence
- (2013) Q. Xie et al. CANCER RESEARCH
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- The Fractalkine/CX3CR1 System Regulates β Cell Function and Insulin Secretion
- (2013) Yun Sok Lee et al. CELL
- A New Development in Senescence
- (2013) Ana Banito et al. CELL
- Programmed Cell Senescence during Mammalian Embryonic Development
- (2013) Daniel Muñoz-Espín et al. CELL
- Senescence Is a Developmental Mechanism that Contributes to Embryonic Growth and Patterning
- (2013) Mekayla Storer et al. CELL
- A Neo-Substrate that Amplifies Catalytic Activity of Parkinson’s-Disease-Related Kinase PINK1
- (2013) Nicholas T. Hertz et al. CELL
- Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism
- (2013) Filipe Cabreiro et al. CELL
- KSR2 Mutations Are Associated with Obesity, Insulin Resistance, and Impaired Cellular Fuel Oxidation
- (2013) Laura R. Pearce et al. CELL
- Radiation-induced cellular senescence results from a slippage of long-term G2arrested cells into G1phase
- (2013) Caiyong Ye et al. CELL CYCLE
- Co-regulation of senescence-associated genes by oncogenic homeobox proteins and polycomb repressive complexes
- (2013) Nadine Martin et al. CELL CYCLE
- Mechanisms that Regulate Stem Cell Aging and Life Span
- (2013) Robert A.J. Signer et al. Cell Stem Cell
- -Cell Dysfunction Due to Increased ER Stress in a Stem Cell Model of Wolfram Syndrome
- (2013) L. Shang et al. DIABETES
- The THO complex component Thp2 counteracts telomeric R-loops and telomere shortening
- (2013) Verena Pfeiffer et al. EMBO JOURNAL
- FOXA1 mediates p16INK4a activation during cellular senescence
- (2013) Qian Li et al. EMBO JOURNAL
- Loss of iron triggers PINK1/Parkin-independent mitophagy
- (2013) George F G Allen et al. EMBO REPORTS
- Cell fusion induced by ERVWE1 or measles virus causes cellular senescence
- (2013) A. Chuprin et al. GENES & DEVELOPMENT
- Germline mutations of regulator of telomere elongation helicase 1, RTEL1, in Dyskeratosis congenita
- (2013) Bari J. Ballew et al. HUMAN GENETICS
- Dyskeratosis congenita mutations in dyskerin SUMOylation consensus sites lead to impaired telomerase RNA accumulation and telomere defects
- (2013) Marie Eve Brault et al. HUMAN MOLECULAR GENETICS
- Association Between Telomere Length and Experimentally Induced Upper Respiratory Viral Infection in Healthy Adults
- (2013) Sheldon Cohen et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- A Dimeric PINK1-containing Complex on Depolarized Mitochondria Stimulates Parkin Recruitment
- (2013) Kei Okatsu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Multi-parameter single-cell kinetic analysis reveals multiple modes of cell death in primary pancreatic -cells
- (2013) Y. H. C. Yang et al. JOURNAL OF CELL SCIENCE
- p16INK4a protects against dysfunctional telomere–induced ATR-dependent DNA damage responses
- (2013) Yang Wang et al. JOURNAL OF CLINICAL INVESTIGATION
- Cellular senescence and the senescent secretory phenotype: therapeutic opportunities
- (2013) Tamara Tchkonia et al. JOURNAL OF CLINICAL INVESTIGATION
- Brain Human Monoclonal Autoantibody from Sydenham Chorea Targets Dopaminergic Neurons in Transgenic Mice and Signals Dopamine D2 Receptor: Implications in Human Disease
- (2013) C. J. Cox et al. JOURNAL OF IMMUNOLOGY
- The Parkinson's disease-associated genePINK1protects neurons from ischemic damage by decreasing mitochondrial translocation of the fission promoter Drp1
- (2013) Yanxin Zhao et al. JOURNAL OF NEUROCHEMISTRY
- Effect of comprehensive lifestyle changes on telomerase activity and telomere length in men with biopsy-proven low-risk prostate cancer: 5-year follow-up of a descriptive pilot study
- (2013) Dean Ornish et al. LANCET ONCOLOGY
- Mitochondrial dysfunction in long-term neuronal cultures mimics changes with aging
- (2013) Weiguo Dong et al. MEDICAL SCIENCE MONITOR
- BRG1 Is Required for Formation of Senescence-Associated Heterochromatin Foci Induced by Oncogenic RAS or BRCA1 Loss
- (2013) Zhigang Tu et al. MOLECULAR AND CELLULAR BIOLOGY
- Parkin-Dependent Degradation of the F-Box Protein Fbw7 Promotes Neuronal Survival in Response to Oxidative Stress by Stabilizing Mcl-1
- (2013) S. Ekholm-Reed et al. MOLECULAR AND CELLULAR BIOLOGY
- Telomeric Noncoding RNA TERRA Is Induced by Telomere Shortening to Nucleate Telomerase Molecules at Short Telomeres
- (2013) Emilio Cusanelli et al. MOLECULAR CELL
- A Posttranslational Modification Cascade Involving p38, Tip60, and PRAK Mediates Oncogene-Induced Senescence
- (2013) Hui Zheng et al. MOLECULAR CELL
- The E3 Ligase Parkin Maintains Mitochondrial Integrity by Increasing Linear Ubiquitination of NEMO
- (2013) Anne Kathrin Müller-Rischart et al. MOLECULAR CELL
- The Telomere Deprotection Response Is Functionally Distinct from the Genomic DNA Damage Response
- (2013) Anthony J. Cesare et al. MOLECULAR CELL
- AMPK Regulates ER Morphology and Function in Stressed Pancreatic β-Cells via Phosphorylation of DRP1
- (2013) Jakob D. Wikstrom et al. MOLECULAR ENDOCRINOLOGY
- Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence
- (2013) Peng Jiang et al. NATURE
- mTOR is a key modulator of ageing and age-related disease
- (2013) Simon C. Johnson et al. NATURE
- Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
- (2013) Shin Yoshimoto et al. NATURE
- A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence
- (2013) Joanna Kaplon et al. NATURE
- Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
- (2013) Shireen A. Sarraf et al. NATURE
- The ubiquitin ligase parkin mediates resistance to intracellular pathogens
- (2013) Paolo S. Manzanillo et al. NATURE
- Diversity of ageing across the tree of life
- (2013) Owen R. Jones et al. NATURE
- The architecture of Tetrahymena telomerase holoenzyme
- (2013) Jiansen Jiang et al. NATURE
- Germline mitochondrial DNA mutations aggravate ageing and can impair brain development
- (2013) Jaime M. Ross et al. NATURE
- High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy
- (2013) Samuel A. Hasson et al. NATURE
- A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity
- (2013) Miki Okada-Iwabu et al. NATURE
- Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders
- (2013) Ruisheng Song et al. NATURE
- Transmitting senescence to the cell neighbourhood
- (2013) Matthew Hoare et al. NATURE CELL BIOLOGY
- Role of telomere dysfunction in cardiac failure in Duchenne muscular dystrophy
- (2013) Foteini Mourkioti et al. NATURE CELL BIOLOGY
- A complex secretory program orchestrated by the inflammasome controls paracrine senescence
- (2013) Juan Carlos Acosta et al. NATURE CELL BIOLOGY
- Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
- (2013) Stig E Bojesen et al. NATURE GENETICS
- Identification of seven loci affecting mean telomere length and their association with disease
- (2013) Veryan Codd et al. NATURE GENETICS
- The Parkinson's disease–linked proteins Fbxo7 and Parkin interact to mediate mitophagy
- (2013) Victoria S Burchell et al. NATURE NEUROSCIENCE
- Structure of active dimeric human telomerase
- (2013) Anselm Sauerwald et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence
- (2013) Bettina Balk et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A three-state model for the regulation of telomerase by TERRA and hnRNPA1
- (2013) Sophie Redon et al. NUCLEIC ACIDS RESEARCH
- PPARβ/δ promotes HRAS-induced senescence and tumor suppression by potentiating p-ERK and repressing p-AKT signaling
- (2013) B Zhu et al. ONCOGENE
- MOZ increases p53 acetylation and premature senescence through its complex formation with PML
- (2013) S. Rokudai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inherited mutations in the helicase RTEL1 cause telomere dysfunction and Hoyeraal–Hreidarsson syndrome
- (2013) Zhong Deng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria
- (2013) Y. Chen et al. SCIENCE
- Aconitase Causes Iron Toxicity in Drosophila pink1 Mutants
- (2013) Giovanni Esposito et al. PLoS Genetics
- Physical Activity, Sedentary Behavior, and Leukocyte Telomere Length in Women
- (2012) M. Du et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Aging, Cellular Senescence, and Cancer
- (2012) Judith Campisi Annual Review of Physiology
- Assessing Cell and Organ Senescence Biomarkers
- (2012) Bruno Bernardes de Jesus et al. CIRCULATION RESEARCH
- Sprouting a new take on stem cell aging
- (2012) Joseph T Rodgers et al. EMBO JOURNAL
- Formation of telomeric repeat-containing RNA (TERRA) foci in highly proliferating mouse cerebellar neuronal progenitors and medulloblastoma
- (2012) Z. Deng et al. JOURNAL OF CELL SCIENCE
- Regulation of telomere length and homeostasis by telomerase enzyme processivity
- (2012) Y. D'Souza et al. JOURNAL OF CELL SCIENCE
- Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
- (2012) Congcong He et al. NATURE
- A metagenome-wide association study of gut microbiota in type 2 diabetes
- (2012) Junjie Qin et al. NATURE
- A PPARγ–FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis
- (2012) Johan W. Jonker et al. NATURE
- ZRF1 controls oncogene-induced senescence through the INK4-ARF locus
- (2012) J D Ribeiro et al. ONCOGENE
- Carcinogen-specific mutational and epigenetic alterations in INK4A, INK4B and p53 tumour-suppressor genes drive induced senescence bypass in normal diploid mammalian cells
- (2012) H Yasaei et al. ONCOGENE
- N terminus of ASPP2 binds to Ras and enhances Ras/Raf/MEK/ERK activation to promote oncogene-induced senescence
- (2012) Z. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) induces cancer cell senescence by interacting with telomerase RNA component
- (2012) C. Nicholls et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
- (2012) Graeme Hewitt et al. Nature Communications
- TERRA Promotes Telomere Shortening through Exonuclease 1–Mediated Resection of Chromosome Ends
- (2012) Verena Pfeiffer et al. PLoS Genetics
- Collapse of Telomere Homeostasis in Hematopoietic Cells Caused by Heterozygous Mutations in Telomerase Genes
- (2012) Geraldine Aubert et al. PLoS Genetics
- A New Definition of Aging?
- (2012) Thomas Flatt Frontiers in Genetics
- Pulmonary Artery Smooth Muscle Cell Senescence Is a Pathogenic Mechanism for Pulmonary Hypertension in Chronic Lung Disease
- (2011) Hibo Noureddine et al. CIRCULATION RESEARCH
- Potential Role of Regulatory T Cells in Reversing Obesity-Linked Insulin Resistance and Diabetic Nephropathy
- (2011) Kathrin Eller et al. DIABETES
- TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA
- (2011) Rachel Litman Flynn et al. NATURE
- Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
- (2011) Tae-Won Kang et al. NATURE
- Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
- (2011) Darren J. Baker et al. NATURE
- Ancestral Mutation in Telomerase Causes Defects in Repeat Addition Processivity and Manifests As Familial Pulmonary Fibrosis
- (2011) Jonathan K. Alder et al. PLoS Genetics
- Regulation of telomerase activity by apparently opposing elements
- (2010) Jun-Ping Liu et al. AGEING RESEARCH REVIEWS
- The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
- (2010) Jean-Philippe Coppé et al. Annual Review of Pathology-Mechanisms of Disease
- Senescence-associated beta-galactosidase activity expression in aging hippocampal neurons
- (2010) Yi-Qun Geng et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging
- (2010) Fabio Demontis et al. CELL
- Telomere protein complexes and interactions with telomerase in telomere maintenance
- (2010) Alexander Ruvantha Pinto Frontiers in Bioscience-Landmark
- Functional interaction between telomere protein TPP1 and telomerase
- (2010) A. J. Zaug et al. GENES & DEVELOPMENT
- Biodemography of human ageing
- (2010) James W. Vaupel NATURE
- A novel motif in telomerase reverse transcriptase regulates telomere repeat addition rate and processivity
- (2010) Mingyi Xie et al. NUCLEIC ACIDS RESEARCH
- Function of Apollo (SNM1B) at telomere highlighted by a splice variant identified in a patient with Hoyeraal-Hreidarsson syndrome
- (2010) F. Touzot et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The association between leukocyte telomere length and cigarette smoking, dietary and physical variables, and risk of prostate cancer
- (2009) Lisa Mirabello et al. AGING CELL
- Syndromes of Telomere Shortening
- (2009) Mary Armanios Annual Review of Genomics and Human Genetics
- Activin inhibits telomerase activity in cancer
- (2009) Indzi Katik et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- KSR2 Is an Essential Regulator of AMP Kinase, Energy Expenditure, and Insulin Sensitivity
- (2009) Diane L. Costanzo-Garvey et al. Cell Metabolism
- Strategies of treating cancer by cytokine regulation of chromosome end remodelling
- (2009) Jun-Ping Liu et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Short Telomeres and Prognosis of Hypertension in a Chinese Population
- (2009) Zhiwei Yang et al. HYPERTENSION
- Telomere Diseases
- (2009) Rodrigo T. Calado et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Human Telomerase Holoenzyme Protein Required for Cajal Body Localization and Telomere Synthesis
- (2009) A. S. Venteicher et al. SCIENCE
- TINF2 mutations result in very short telomeres: analysis of a large cohort of patients with dyskeratosis congenita and related bone marrow failure syndromes
- (2008) A. J. Walne et al. BLOOD
- Bone Morphogenetic Protein-7 Inhibits Telomerase Activity, Telomere Maintenance, and Cervical Tumor Growth
- (2008) L. Cassar et al. CANCER RESEARCH
- Estrogen deficiency leads to telomerase inhibition, telomere shortening and reduced cell proliferation in the adrenal gland of mice
- (2008) Sharyn Bayne et al. CELL RESEARCH
- Association of Leukocyte Telomere Length With Circulating Biomarkers of the Renin-Angiotensin-Aldosterone System
- (2008) Ramachandran S. Vasan et al. CIRCULATION
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