Immunosuppressive Tryptophan Catabolism and Gut Mucosal Dysfunction Following Early HIV Infection

Soluble CD40-ligand (sCD40L, sCD154) plays an immunosuppressive role via regulatory T cell expansion in HIV infection

(2014) M.-A. Jenabian et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The Kynurenine Pathway of Tryptophan Catabolism, CD4+ T-Cell Recovery, and Mortality Among HIV-Infected Ugandans Initiating Antiretroviral Therapy

(2014) H. Byakwaga et al.   JOURNAL OF INFECTIOUS DISEASES

Gut Epithelial Barrier Dysfunction and Innate Immune Activation Predict Mortality in Treated HIV Infection

(2014) Peter W. Hunt et al.   JOURNAL OF INFECTIOUS DISEASES

HIV infection: epidemiology, pathogenesis, treatment, and prevention

(2014) Gary Maartens et al.   LANCET

Early initiation of combined antiretroviral therapy preserves immune function in the gut of HIV-infected patients

(2014) A Kök et al.   Mucosal Immunology

The liver as a firewall—clearance of commensal bacteria that have escaped from the gut

(2014) Natalie J. Wood   Nature Reviews Gastroenterology & Hepatology

Anti-Retroviral Therapy Decreases but Does Not Normalize Indoleamine 2,3-Dioxygenase Activity in HIV-Infected Patients

(2014) Jun Chen et al.   PLoS One

The Liver May Act as a Firewall Mediating Mutualism Between the Host and Its Gut Commensal Microbiota

(2014) M. L. Balmer et al.   Science Translational Medicine

Immunosenescence and aging in HIV

(2014) Chris Tsoukas   Current Opinion in HIV and AIDS

Decreases in Colonic and Systemic Inflammation in Chronic HIV Infection after IL-7 Administration

(2014) Irini Sereti et al.   PLoS Pathogens

HIV-Infected Individuals with Low CD4/CD8 Ratio despite Effective Antiretroviral Therapy Exhibit Altered T Cell Subsets, Heightened CD8+ T Cell Activation, and Increased Risk of Non-AIDS Morbidity and Mortality

(2014) Sergio Serrano-Villar et al.   PLoS Pathogens

Oral serum-derived bovine immunoglobulin improves duodenal immune reconstitution and absorption function in patients with HIV enteropathy

(2013) David M. Asmuth et al.   AIDS

Serum I-FABP as marker for enterocyte damage in coeliac disease and its relation to villous atrophy and circulating autoantibodies

(2013) M. P. M. Adriaanse et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

(2013) Teresa Zelante et al.   IMMUNITY

Systemic Effects of Inflammation on Health during Chronic HIV Infection

(2013) Steven G. Deeks et al.   IMMUNITY

Longitudinal Analysis of Distribution and Function of Plasmacytoid Dendritic Cells in Peripheral Blood and Gut Mucosa of HIV Infected Patients

(2013) C. Lehmann et al.   JOURNAL OF INFECTIOUS DISEASES

ST2 as a Marker for Risk of Therapy-Resistant Graft-versus-Host Disease and Death

(2013) Mark T. Vander Lugt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Distinct Tryptophan Catabolism and Th17/Treg Balance in HIV Progressors and Elite Controllers

(2013) Mohammad-Ali Jenabian et al.   PLoS One

Dysbiosis of the Gut Microbiota Is Associated with HIV Disease Progression and Tryptophan Catabolism

(2013) Ivan Vujkovic-Cvijin et al.   Science Translational Medicine

The Th17/Treg Ratio, IL-1RA and sCD14 Levels in Primary HIV Infection Predict the T-cell Activation Set Point in the Absence of Systemic Microbial Translocation

(2013) Mathieu F. Chevalier et al.   PLoS Pathogens

Post-Treatment HIV-1 Controllers with a Long-Term Virological Remission after the Interruption of Early Initiated Antiretroviral Therapy ANRS VISCONTI Study

(2013) Asier Sáez-Cirión et al.   PLoS Pathogens

HIV-1 control after transient antiretroviral treatment initiated in primary infection: role of patient characteristics and effect of therapy

(2012) Cécile Goujard et al.   ANTIVIRAL THERAPY

Temporary antiretroviral treatment during primary HIV-1 infection has a positive impact on health-related quality of life: data from the Primo-SHM cohort study

(2012) ML Grijsen et al.   HIV MEDICINE

Human immunodeficiency virus and the gastrointestinal immune system: does highly active antiretroviral therapy restore gut immunity?

(2012) C T Costiniuk et al.   Mucosal Immunology

Microbial translocation in HIV infection: causes, consequences and treatment opportunities

(2012) Netanya G. Sandler et al.   NATURE REVIEWS MICROBIOLOGY

Acute Plasma Biomarkers of T Cell Activation Set-Point Levels and of Disease Progression in HIV-1 Infection

(2012) Anne-Sophie Liovat et al.   PLoS One

Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection

(2012) N. M. Archin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Indoleamine 2,3 dioxygenase and metabolic control of immune responses

(2012) David H. Munn et al.   TRENDS IN IMMUNOLOGY

Soluble biomarkers of HIV transmission, disease progression and comorbidities

(2012) Edwin Leeansyah et al.   Current Opinion in HIV and AIDS

No Treatment versus 24 or 60 Weeks of Antiretroviral Treatment during Primary HIV Infection: The Randomized Primo-SHM Trial

(2012) Marlous L. Grijsen et al.   PLOS MEDICINE

Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections

(2011) Ming Zeng et al.   JOURNAL OF CLINICAL INVESTIGATION

Additional value of serum I-FABP levels for evaluating celiac disease activity in children

(2011) Anita C Vreugdenhil et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Soluble ST2: A new and promising activity marker in ulcerative colitis

(2011) David Díaz-Jiménez   WORLD JOURNAL OF GASTROENTEROLOGY

Tryptophan metabolism, from nutrition to potential therapeutic applications

(2010) Nathalie Le Floc’h et al.   AMINO ACIDS

Development of selective immune tolerance towards the allogeneic fetus during pregnancy: Role of tryptophan catabolites (Review)

(2010) Zhu   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

High Levels of Soluble ST2 and Low Levels of IL-33 in Sera of Patients with HIV Infection

(2010) Tomomitsu Miyagaki et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Tryptophan Catabolism by Indoleamine 2,3-Dioxygenase 1 Alters the Balance of TH17 to Regulatory T Cells in HIV Disease

(2010) D. Favre et al.   Science Translational Medicine

α4+β7hiCD4+ memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection

(2009) M Kader et al.   Mucosal Immunology

Microbial Translocation Is Associated with Increased Monocyte Activation and Dementia in AIDS Patients

(2008) Petronela Ancuta et al.   PLoS One