Adjuvants Based on Hybrid Antibiotics Overcome Resistance in Pseudomonas aeruginosa and Enhance Fluoroquinolone Efficacy

Amphiphilic Tobramycins with Immunomodulatory Properties

(2015) Goutam Guchhait et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Two Mechanisms of Killing of Pseudomonas aeruginosa by Tobramycin Assessed at Multiple Inocula via Mechanism-Based Modeling

(2015) Jürgen B. Bulitta et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Tobramycin and Nebramine as Pseudo-oligosaccharide Scaffolds for the Development of Antimicrobial Cationic Amphiphiles

(2015) Yifat Berkov-Zrihen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enhanced efficacy of putative efflux pump inhibitor/antibiotic combination treatments versus MDR strains ofPseudomonas aeruginosain aGalleria mellonella in vivoinfection model

(2015) Dougal H. Adamson et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

New Amphiphilic Neamine Derivatives Active against Resistant Pseudomonas aeruginosa and Their Interactions with Lipopolysaccharides

(2014) Guillaume Sautrey et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Galleria mellonella infection model reveals double and triple antibiotic combination therapies with enhanced efficacy versus a multidrug-resistant strain of Pseudomonas aeruginosa

(2014) J. Krezdorn et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Tuning the Antibacterial Activity of Amphiphilic Neamine Derivatives and Comparison to Paromamine Homologues

(2013) Louis Zimmermann et al.   JOURNAL OF MEDICINAL CHEMISTRY

6′′-Thioether Tobramycin Analogues: Towards Selective Targeting of Bacterial Membranes

(2012) Ido M. Herzog et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Determinants of Intrinsic Aminoglycoside Resistance in Pseudomonas aeruginosa

(2012) Thomas Krahn et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibiotic adjuvants: multicomponent anti-infective strategies

(2011) Lindsay Kalan et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Pseudomonas aeruginosa: all roads lead to resistance

(2011) Elena B.M. Breidenstein et al.   TRENDS IN MICROBIOLOGY

Dual-acting hybrid antibiotics: a promising strategy to combat bacterial resistance

(2010) Varvara Pokrovskaya et al.   Expert Opinion on Drug Discovery

Design, Synthesis, and Evaluation of Novel Fluoroquinolone−Aminoglycoside Hybrid Antibiotics

(2009) Varvara Pokrovskaya et al.   JOURNAL OF MEDICINAL CHEMISTRY

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Induction by Cationic Antimicrobial Peptides and Involvement in Intrinsic Polymyxin and Antimicrobial Peptide Resistance, Biofilm Formation, and Swarming Motility of PsrA in Pseudomonas aeruginosa

(2008) W. J. Gooderham et al.   JOURNAL OF BACTERIOLOGY