Tobramycin and Nebramine as Pseudo-oligosaccharide Scaffolds for the Development of Antimicrobial Cationic Amphiphiles

New Amphiphilic Neamine Derivatives Active against Resistant Pseudomonas aeruginosa and Their Interactions with Lipopolysaccharides

(2014) Guillaume Sautrey et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Design and synthesis of membrane-targeting antibiotics: from peptides- to aminosugar-based antimicrobial cationic amphiphiles

(2014) Ido M. Herzog et al.   MedChemComm

Di-alkylated paromomycin derivatives: Targeting the membranes of Gram positive pathogens that cause skin infections

(2013) Yifat Berkov-Zrihen et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design and Synthesis of Amphiphilic Xanthone-Based, Membrane-Targeting Antimicrobials with Improved Membrane Selectivity

(2013) Hanxun Zou et al.   JOURNAL OF MEDICINAL CHEMISTRY

Site-Selective Displacement of Tobramycin Hydroxyls for Preparation of Antimicrobial Cationic Amphiphiles

(2013) Yifat Berkov-Zrihen et al.   ORGANIC LETTERS

Antibiotic development challenges: the various mechanisms of action of antimicrobial peptides and of bacterial resistance

(2013) Fernanda Guilhelmelli et al.   Frontiers in Microbiology

6′′-Thioether Tobramycin Analogues: Towards Selective Targeting of Bacterial Membranes

(2012) Ido M. Herzog et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DCAP: A Broad-Spectrum Antibiotic That Targets the Cytoplasmic Membrane of Bacteria

(2012) Ye-Jin Eun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design of membrane targeting tobramycin-based cationic amphiphiles with reduced hemolytic activity

(2012) Ido M. Herzog et al.   MedChemComm

The Pseudomonas aeruginosa membranes: A target for a new amphiphilic aminoglycoside derivative?

(2011) Myriam Ouberai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Cationic Amphiphiles, a New Generation of Antimicrobials Inspired by the Natural Antimicrobial Peptide Scaffold

(2010) B. Findlay et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Targeting bacterial membrane function: an underexploited mechanism for treating persistent infections

(2010) Julian G. Hurdle et al.   NATURE REVIEWS MICROBIOLOGY

Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa

(2010) N. Srinivas et al.   SCIENCE

Design, Synthesis, and Structure−Activity Relationships of Benzophenone-Based Tetraamides as Novel Antibacterial Agents

(2009) Sunil K. Vooturi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Ceragenins: Cholic Acid-Based Mimics of Antimicrobial Peptides

(2008) Xin-Zhong Lai et al.   ACCOUNTS OF CHEMICAL RESEARCH

Capsule polysaccharide is a bacterial decoy for antimicrobial peptides

(2008) E. Llobet et al.   MICROBIOLOGY-SGM