6′′-Thioether Tobramycin Analogues: Towards Selective Targeting of Bacterial Membranes

Roles of Hydrophobicity and Charge Distribution of Cationic Antimicrobial Peptides in Peptide-Membrane Interactions

(2012) Lois M. Yin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of Altering Aminoglycoside Structures on Bacterial Resistance Enzyme Activities

(2011) Keith D. Green et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Pseudomonas aeruginosa membranes: A target for a new amphiphilic aminoglycoside derivative?

(2011) Myriam Ouberai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Beyond natural antimicrobial peptides: multimeric peptides and other peptidomimetic approaches

(2011) Andrea Giuliani et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Inhibition of Aminoglycoside-Deactivating Enzymes APH(3′)-IIIa and AAC(6′)-Ii by Amphiphilic Paromomycin O2′′-Ether Analogues

(2011) Janek Szychowski et al.   ChemMedChem

Identification and Characterization of Inhibitors of the Aminoglycoside Resistance Acetyltransferase Eis from Mycobacterium tuberculosis

(2011) Keith D. Green et al.   ChemMedChem

Unusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TB

(2011) W. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cationic Amphiphiles, a New Generation of Antimicrobials Inspired by the Natural Antimicrobial Peptide Scaffold

(2010) B. Findlay et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Dissecting the cosubstrate structure requirements of the Staphylococcus aureus aminoglycoside resistance enzyme ANT(4′)

(2010) Vanessa R. Porter et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structure-based design, synthesis and A-site rRNA co-crystal complexes of novel amphiphilic aminoglycoside antibiotics with new binding modes: A synergistic hydrophobic effect against resistant bacteria

(2010) Stephen Hanessian et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Future of Aminoglycosides: The End or Renaissance?

(2010) Jacob L. Houghton  et al.   CHEMBIOCHEM

Antibacterial Activities of Aminoglycoside Antibiotics-Derived Cationic Amphiphiles. Polyol-Modified Neomycin B-, Kanamycin A-, Amikacin-, and Neamine-Based Amphiphiles with Potent Broad Spectrum Antibacterial Activity

(2010) Smritilekha Bera et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Antimicrobial Evaluation of Amphiphilic Neamine Derivatives

(2009) Isabelle Baussanne et al.   JOURNAL OF MEDICINAL CHEMISTRY