标题
The Bacterial Type III Secretion System as a Target for Developing New Antibiotics
作者
关键词
-
出版物
Chemical Biology & Drug Design
Volume 85, Issue 1, Pages 30-42
出版商
Wiley
发表日期
2014-12-20
DOI
10.1111/cbdd.12422
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mutations in the Pseudomonas aeruginosa Needle Protein GenepscFConfer Resistance to Phenoxyacetamide Inhibitors of the Type III Secretion System
- (2014) Nicholas O. Bowlin et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Building a secreting nanomachine: a structural overview of the T3SS
- (2014) Patrizia Abrusci et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- The gallium(III)–salicylidene acylhydrazide complex shows synergistic anti-biofilm effect and inhibits toxin production by Pseudomonas aeruginosa
- (2014) Olena Rzhepishevska et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Targeting virulence: can we make evolution-proof drugs?
- (2014) Richard C. Allen et al. NATURE REVIEWS MICROBIOLOGY
- LcrQ Blocks the Role of LcrF in Regulating the Ysc-Yop Type III Secretion Genes in Yersinia pseudotuberculosis
- (2014) Lamei Li et al. PLoS One
- Overcoming the current deadlock in antibiotic research
- (2014) Till F. Schäberle et al. TRENDS IN MICROBIOLOGY
- The SPI-1-like Type III secretion system: more roles than you think
- (2014) Frank Egan et al. Frontiers in Plant Science
- Cytosporone B, an Inhibitor of the Type III Secretion System of Salmonella enterica Serovar Typhimurium
- (2013) Jianfang Li et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A Type III Secretion System Inhibitor Targets YopD while Revealing Differential Regulation of Secretion in Calcium-Blind Mutants of Yersinia pestis
- (2013) Danielle L. Jessen et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- An NF-κB-Based High-Throughput Screen Identifies Piericidins as Inhibitors of the Yersinia pseudotuberculosis Type III Secretion System
- (2013) Miles C. Duncan et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- N-Terminus of IpaB Provides a Potential Anchor to the Shigella Type III Secretion System Tip Complex Protein IpaD
- (2013) Nicholas E. Dickenson et al. BIOCHEMISTRY
- Structure and Biophysics of Type III Secretion in Bacteria
- (2013) Srirupa Chatterjee et al. BIOCHEMISTRY
- A novel effector secretion mechanism based on proton-motive force-dependent type III secretion apparatus rotation
- (2013) Takashi Ohgita et al. FASEB JOURNAL
- Small-Molecule Inhibitor of the Shigella flexneri Master Virulence Regulator VirF
- (2013) Veerendra Koppolu et al. INFECTION AND IMMUNITY
- Antibiotics in the clinical pipeline in 2013
- (2013) Mark S Butler et al. JOURNAL OF ANTIBIOTICS
- Mutations in hemG Mediate Resistance to Salicylidene Acylhydrazides, Demonstrating a Novel Link between Protoporphyrinogen Oxidase (HemG) and Chlamydia trachomatis Infectivity
- (2013) P. Engstrom et al. JOURNAL OF BACTERIOLOGY
- The role of the natural environment in the emergence of antibiotic resistance in Gram-negative bacteria
- (2013) Elizabeth MH Wellington et al. LANCET INFECTIOUS DISEASES
- Isolation of Salmonella Mutants Resistant to the Inhibitory Effect of Salicylidene acylhydrazides on Flagella-Mediated Motility
- (2013) Isabel Martinez-Argudo et al. PLoS One
- Diverse Secreted Effectors Are Required for Salmonella Persistence in a Mouse Infection Model
- (2013) Afshan S. Kidwai et al. PLoS One
- The Resveratrol Tetramer (-)-Hopeaphenol Inhibits Type III Secretion in the Gram-Negative Pathogens Yersinia pseudotuberculosis and Pseudomonas aeruginosa
- (2013) Caroline E. Zetterström et al. PLoS One
- Identification of Salmonella Pathogenicity Island-2 Type III Secretion System Effectors Involved in Intramacrophage Replication of S. enterica Serovar Typhimurium: Implications for Rational Vaccine Design
- (2013) R. Figueira et al. mBio
- New antibiotics for bad bugs: where are we?
- (2013) Matteo Bassetti et al. Annals of Clinical Microbiology and Antimicrobials
- Suppression of type III effector secretion by polymers
- (2013) T. Ohgita et al. Open Biology
- The Common Structural Architecture of Shigella flexneri and Salmonella typhimurium Type Three Secretion Needles
- (2013) Jean-Philippe Demers et al. PLoS Pathogens
- Chemical Inhibitors of the Type Three Secretion System: Disarming Bacterial Pathogens
- (2012) Miles C. Duncan et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Derivatives of 8-hydroxyquinoline—antibacterial agents that target intra- and extracellular Gram-negative pathogens
- (2012) Per-Anders Enquist et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Shigella Effector IpaB-Induced Cholesterol Relocation Disrupts the Golgi Complex and Recycling Network to Inhibit Host Cell Secretion
- (2012) Joëlle Mounier et al. Cell Host & Microbe
- Pre-clinical pharmacokinetics and anti-chlamydial activity of salicylidene acylhydrazide inhibitors of bacterial type III secretion
- (2012) Tofeeq Ur-Rehman et al. JOURNAL OF ANTIBIOTICS
- Functions of the Salmonella pathogenicity island 2 (SPI-2) type III secretion system effectors
- (2012) R. Figueira et al. MICROBIOLOGY-SGM
- Architecture of the major component of the type III secretion system export apparatus
- (2012) Patrizia Abrusci et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural Characterisation of Tpx from Yersinia pseudotuberculosis Reveals Insights into the Binding of Salicylidene Acylhydrazide Compounds
- (2012) Mads Gabrielsen et al. PLoS One
- Optimizing ring assembly reveals the strength of weak interactions
- (2012) E. J. Deeds et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Distribution and diversity of bacterial secretion systems across metagenomic datasets
- (2012) Matthieu Barret et al. Environmental Microbiology Reports
- Novel classes of antibiotics or more of the same?
- (2011) Anthony RM Coates et al. BRITISH JOURNAL OF PHARMACOLOGY
- Small-molecular virulence inhibitors show divergent and immunomodulatory effects in infection models of Salmonella enterica serovar Typhimurium
- (2011) Speranta Puiac et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Identification of Bacterial Target Proteins for the Salicylidene Acylhydrazide Class of Virulence-blocking Compounds
- (2011) Dai Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Protection of Mice From a Chlamydia trachomatis Vaginal Infection Using a Salicylidene Acylhydrazide, a Potential Microbicide
- (2011) A. Slepenkin et al. JOURNAL OF INFECTIOUS DISEASES
- Pseudoceramines A–D, new antibacterial bromotyrosine alkaloids from the marine sponge Pseudoceratina sp.
- (2011) Sheng Yin et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Transcriptional Priming of Salmonella Pathogenicity Island-2 Precedes Cellular Invasion
- (2011) Suzanne E. Osborne et al. PLoS One
- Identification of Small-Molecule Inhibitors of Yersinia pestis Type III Secretion System YscN ATPase
- (2011) Wieslaw Swietnicki et al. PLoS One
- Identification of the bile salt binding site on ipad from Shigella flexneri and the influence of ligand binding on IpaD structure
- (2011) Michael L. Barta et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Biogenesis, Regulation, and Targeting of the Type III Secretion System
- (2011) Thierry Izoré et al. STRUCTURE
- Chlamydia Pneumoniae CdsL Regulates CdsN ATPase Activity, and Disruption with a Peptide Mimetic Prevents Bacterial Invasion
- (2011) Chris B. Stone et al. Frontiers in Microbiology
- Identification and Characterization of Small-Molecule Inhibitors of Yop Translocation in Yersinia pseudotuberculosis
- (2010) D. E. Harmon et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Discovery and Characterization of Inhibitors of Pseudomonas aeruginosa Type III Secretion
- (2010) D. Aiello et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- NMR Characterization of the Interaction of theSalmonellaType III Secretion System Protein SipD and Bile Salts,
- (2010) Yu Wang et al. BIOCHEMISTRY
- Conformational Changes in IpaD fromShigella flexneriupon Binding Bile Salts Provide Insight into the Second Step of Type III Secretion
- (2010) Nicholas E. Dickenson et al. BIOCHEMISTRY
- Effect of bovine lactoferrin in Salmonella ser. Typhimurium infection in mice
- (2010) Susan Mosquito et al. BIOMETALS
- Statistical molecular design of a focused salicylidene acylhydrazide library and multivariate QSAR of inhibition of type III secretion in the Gram-negative bacterium Yersinia
- (2010) Markus K. Dahlgren et al. BIOORGANIC & MEDICINAL CHEMISTRY
- N-Hydroxybenzimidazole inhibitors of ExsA MAR transcription factor in Pseudomonas aeruginosa: In vitro anti-virulence activity and metabolic stability
- (2010) Mark C. Grier et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Principles of early drug discovery
- (2010) JP Hughes et al. BRITISH JOURNAL OF PHARMACOLOGY
- The 10 × ‘20 Initiative: Pursuing a Global Commitment to Develop 10 New Antibacterial Drugs by 2020
- (2010) CLINICAL INFECTIOUS DISEASES
- Antivirulence drugs to target bacterial secretion systems
- (2010) Christian Baron CURRENT OPINION IN MICROBIOLOGY
- Membrane targeting and pore formation by the type III secretion system translocon
- (2010) Pierre-Jean Matteï et al. FEBS Journal
- Small Molecule Inhibitors of LcrF, a Yersinia pseudotuberculosis Transcription Factor, Attenuate Virulence and Limit Infection in a Murine Pneumonia Model
- (2010) L. K. Garrity-Ryan et al. INFECTION AND IMMUNITY
- A small-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium
- (2010) Kyota Kimura et al. JOURNAL OF ANTIBIOTICS
- Characterization of the Interaction between theSalmonellaType III Secretion System Tip Protein SipD and the Needle Protein PrgI by Paramagnetic Relaxation Enhancement
- (2010) Thenmalarchelvi Rathinavelan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Escape of intracellular Shigella from autophagy requires binding to cholesterol through the type III effector, IcsB
- (2010) Christian Aimé Kayath et al. MICROBES AND INFECTION
- Origins and Evolution of Antibiotic Resistance
- (2010) J. Davies et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Call of the wild: antibiotic resistance genes in natural environments
- (2010) Heather K. Allen et al. NATURE REVIEWS MICROBIOLOGY
- Designed Coiled-Coil Peptides Inhibit the Type Three Secretion System of Enteropathogenic Escherichia coli
- (2010) Mariano Larzábal et al. PLoS One
- The crystal structures of theSalmonellatype III secretion system tip protein SipD in complex with deoxycholate and chenodeoxycholate
- (2010) Srirupa Chatterjee et al. PROTEIN SCIENCE
- Omeprazole Antagonizes Virulence and Inflammation in Salmonella enterica-Infected RAW264.7 Cells
- (2009) S. Puiac et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Tethered thiazolidinone dimers as inhibitors of the bacterial type III secretion system
- (2009) Toni Kline et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Small molecule inhibitors of the Yersinia type III secretion system impair the development of Chlamydia after entry into host cells
- (2009) Sandra Muschiol et al. BMC MICROBIOLOGY
- Salicylidene acylhydrazide-mediated inhibition of type III secretion system-1 in Salmonella enterica serovar Typhimurium is associated with iron restriction and can be reversed by free iron
- (2009) Abigail N. Layton et al. FEMS MICROBIOLOGY LETTERS
- Characterization of the Effects of Salicylidene Acylhydrazide Compounds on Type III Secretion in Escherichia coli O157:H7
- (2009) J. J. Tree et al. INFECTION AND IMMUNITY
- Liposomes Recruit IpaC to the Shigella flexneri Type III Secretion Apparatus Needle as a Final Step in Secretion Induction
- (2009) C. R. Epler et al. INFECTION AND IMMUNITY
- Guadinomines, Type III Secretion System Inhibitors, Produced by Streptomyces sp. K01-0509
- (2009) Masato Iwatsuki et al. JOURNAL OF ANTIBIOTICS
- N-Hydroxybenzimidazole Inhibitors of the Transcription Factor LcrF inYersinia: Novel Antivirulence Agents
- (2009) Oak K. Kim et al. JOURNAL OF MEDICINAL CHEMISTRY
- A conserved structural motif mediates formation of the periplasmic rings in the type III secretion system
- (2009) Thomas Spreter et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Targeting Type III Secretion in Yersinia pestis
- (2008) N. J. Pan et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Effect of lactoferrin on enteric pathogens
- (2008) T OCHOA et al. BIOCHIMIE
- An Inhibitor of Gram-Negative Bacterial Virulence Protein Secretion
- (2008) Heather B. Felise et al. Cell Host & Microbe
- Small-Molecule Type III Secretion System Inhibitors Block Assembly of the Shigella Type III Secreton
- (2008) A. K. J. Veenendaal et al. JOURNAL OF BACTERIOLOGY
- Virulence blockers as alternatives to antibiotics: type III secretion inhibitors against Gram-negative bacteria
- (2008) P. Keyser et al. JOURNAL OF INTERNAL MEDICINE
- Substituted 2-Imino-5-arylidenethiazolidin-4-one Inhibitors of Bacterial Type III Secretion
- (2008) Toni Kline et al. JOURNAL OF MEDICINAL CHEMISTRY
- Esterification of cholesterol by a type III secretion effector during intracellular Salmonella infection
- (2008) Parwez Nawabi et al. MOLECULAR MICROBIOLOGY
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