Plexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions
出版年份 2012 全文链接
标题
Plexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions
作者
关键词
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出版物
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 69, Issue 22, Pages 3765-3805
出版商
Springer Nature
发表日期
2012-06-28
DOI
10.1007/s00018-012-1019-0
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- Structural Insights into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2
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- Specificity of sensory–motor connections encoded by Sema3e–Plxnd1 recognition
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- Secreted semaphorins control spine distribution and morphogenesis in the postnatal CNS
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- FARP1 Promotes the Dendritic Growth of Spinal Motor Neuron Subtypes through Transmembrane Semaphorin6A and PlexinA4 Signaling
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- Plexin B1 is repressed by oncogenic B-Raf signaling and functions as a tumor suppressor in melanoma cells
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- Design of versatile biochemical switches that respond to amplitude, duration, and spatial cues
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- Crystal structure of the plexin A3 intracellular region reveals an autoinhibited conformation through active site sequestration
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- GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling
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- Thermodynamic characterization of two homologous protein complexes: Associations of the semaphorin receptor plexin-B1 RhoGTPase binding domain with Rnd1 and active Rac1
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- Cell Signaling in Space and Time: Where Proteins Come Together and When They're Apart
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- Only a Subset of Met-Activated Pathways Are Required to Sustain Oncogene Addiction
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- Guidance from above: common cues direct distinct signaling outcomes in vascular and neural patterning
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- The neurovascular link in health and disease: an update
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- Neuropilins: structure, function and role in disease
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- The metazoan history of the COE transcription factors. Selection of a variant HLH motif by mandatory inclusion of a duplicated exon in vertebrates
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- Blocking Neuropilin-2 Function Inhibits Tumor Cell Metastasis
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- Targeting Angiogenesis Driven by Vascular Endothelial Growth Factors Using Antibody-Based Therapies
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- Activated G 13 Impairs Cell Invasiveness through p190RhoGAP-Mediated Inhibition of RhoA Activity
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- Breast Tumor Kinase Phosphorylates p190RhoGAP to Regulate Rho and Ras and Promote Breast Carcinoma Growth, Migration, and Invasion
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- Besides adhesion: new perspectives of integrin functions in angiogenesis
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- The many faces of semaphorins: from development to pathology
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- Vascular Endothelial Growth Factor and Semaphorin Induce Neuropilin-1 Endocytosis via Separate Pathways
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- Plexin-A3 and plexin-A4 restrict the migration of sympathetic neurons but not their neural crest precursors
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- Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells
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- Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects
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- Tyrosine phosphorylation in semaphorin signalling: shifting into overdrive
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- Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: Implications for autism and epilepsy
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- Loss of Plexin B1 is highly prognostic in low proliferating ER positive breast cancers – Results of a large scale microarray analysis
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- L1-CAM in cancerous tissues
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- Orf virus VEGF-E NZ2 promotes paracellular NRP-1/VEGFR-2 coreceptor assembly via the peptide RPPR
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- EGFR family: Structure physiology signalling and therapeutic targets†
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- PlexinD1 Glycoprotein Controls Migration of Positively Selected Thymocytes into the Medulla
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- The evolving role of semaphorins and plexins in the immune system: Plexin-A1 regulation of dendritic cell function
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- Metabolic Stress Induces the Lysosomal Degradation of Neuropilin-1 but Not Neuropilin-2
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- ABL2/ARG Tyrosine Kinase Mediates SEMA3F-induced RhoA Inactivation and Cytoskeleton Collapse in Human Glioma Cells
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- Role of Src Signal Transduction Pathways in Scatter Factor-mediated Cellular Protection
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- Rnd1 Regulates Axon Extension by Enhancing the Microtubule Destabilizing Activity of SCG10
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- Rho-kinase Contributes to Sustained RhoA Activation through Phosphorylation of p190A RhoGAP
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- p190RhoGAP is the convergence point of adhesion signals from α5β1integrin and syndecan-4
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- Immune Semaphorins: Novel Features of Neural Guidance Molecules
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- Plexin C1, A Receptor for Semaphorin 7A, Inactivates Cofilin and Is a Potential Tumor Suppressor for Melanoma Progression
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- Compensatory and Long-Range Changes in Picosecond–Nanosecond Main-Chain Dynamics upon Complex Formation: 15N Relaxation Analysis of the Free and Bound States of the Ubiquitin-like Domain of Human Plexin-B1 and the Small GTPase Rac1
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- Targeting Axon Growth from Neuronal Transplants along Preformed Guidance Pathways in the Adult CNS
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- The Semaphorin Receptor PlexinA3 Mediates Neuronal Apoptosis during Dorsal Root Ganglia Development
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- Release of MICAL Autoinhibition by Semaphorin-Plexin Signaling Promotes Interaction with Collapsin Response Mediator Protein
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- Peripheral nerve regeneration is delayed in neuropilin 2-deficient mice
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- Semaphorin 3B Is a 1,25-Dihydroxyvitamin D3-Induced Gene in Osteoblasts that Promotes Osteoclastogenesis and Induces Osteopenia in Mice
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- Plexin-A2 and its ligand, Sema6A, control nucleus-centrosome coupling in migrating granule cells
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- Membrane potential shifts caused by diffusible guidance signals direct growth-cone turning
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- Cyclic GMP-Gated CNG Channels Function in Sema3A-Induced Growth Cone Repulsion
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- Semaphorin 6D regulates the late phase of CD4+ T cell primary immune responses
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- Human Bone Marrow Adipocytes Block Granulopoiesis Through Neuropilin-1-Induced Granulocyte Colony-Stimulating Factor Inhibition
- (2008) Zakia Belaid-Choucair et al. STEM CELLS
- Insights into Oncogenic Mutations of Plexin-B1 Based on the Solution Structure of the Rho GTPase Binding Domain
- (2008) Yufeng Tong et al. STRUCTURE
- Semaphorin signaling: progress made and promises ahead
- (2008) Yeping Zhou et al. TRENDS IN BIOCHEMICAL SCIENCES
- Semaphorin 7a Promotes Spreading and Dendricity in Human Melanocytes through β1-Integrins
- (2007) Glynis A. Scott et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Transmembrane Domain Interactions Control Biological Functions of Neuropilin-1
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