Tumour growth inhibition and anti-metastatic activity of a mutated furin-resistant Semaphorin 3E isoform

Systemic and Targeted Delivery of Semaphorin 3A Inhibits Tumor Angiogenesis and Progression in Mouse Tumor Models

(2011) Andrea Casazza et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Semaphorin 3E-Plexin-D1 signaling regulates VEGF function in developmental angiogenesis via a feedback mechanism

(2011) J. Kim et al.   GENES & DEVELOPMENT

Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice

(2011) Yoko Fukushima et al.   JOURNAL OF CLINICAL INVESTIGATION

Focal adhesion kinase and endothelial cell apoptosis

(2011) Qing Lu et al.   MICROVASCULAR RESEARCH

Differential Endothelial Transcriptomics Identifies Semaphorin 3G as a Vascular Class 3 Semaphorin

(2010) Simone Kutschera et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease

(2010) Sara Van de Veire et al.   CELL

Sema3E–Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice

(2010) Andrea Casazza et al.   JOURNAL OF CLINICAL INVESTIGATION

Semaphorin 3E Initiates Antiangiogenic Signaling through Plexin D1 by Regulating Arf6 and R-Ras

(2010) A. Sakurai et al.   MOLECULAR AND CELLULAR BIOLOGY

Plexin D1 is ubiquitously expressed on tumor vessels and tumor cells in solid malignancies

(2009) Ilse Roodink et al.   BMC CANCER

Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

(2009) John M.L. Ebos et al.   CANCER CELL

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

Role of the hypoxic tumor microenvironment in the resistance to anti-angiogenic therapies

(2009) Annamaria Rapisarda et al.   DRUG RESISTANCE UPDATES

Semaphorin signaling in cancer cells and in cells of the tumor microenvironment - two sides of a coin

(2009) L. Capparuccia et al.   JOURNAL OF CELL SCIENCE

Spheroid-based human endothelial cell microvessel formation in vivo

(2009) Anna M Laib et al.   Nature Protocols

Semaphorin-3B Is an Angiogenesis Inhibitor That Is Inactivated by Furin-Like Pro-Protein Convertases

(2008) A. Varshavsky et al.   CANCER RESEARCH

Tyrosine phosphorylation in semaphorin signalling: shifting into overdrive

(2008) Mélanie Franco et al.   EMBO REPORTS

Regulation of angiogenesis: apoptotic cues from the ECM

(2008) D A Cheresh et al.   ONCOGENE

Successful Inhibition of Tumor Development by Specific Class-3 Semaphorins Is Associated with Expression of Appropriate Semaphorin Receptors by Tumor Cells

(2008) Boaz Kigel et al.   PLoS One

Semaphorin signaling: progress made and promises ahead

(2008) Yeping Zhou et al.   TRENDS IN BIOCHEMICAL SCIENCES