Signal transduction by vascular endothelial growth factor receptors

RACK1 Regulates VEGF/Flt1-mediated Cell Migration via Activation of a PI3K/Akt Pathway

(2011) Feng Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vascular endothelial growth factors and receptors: Anti-angiogenic therapy in the treatment of cancer

(2011) Sònia Tugues et al.   MOLECULAR ASPECTS OF MEDICINE

Akt/Protein Kinase B Is Required for Lymphatic Network Formation, Remodeling, and Valve Development

(2010) Fei Zhou et al.   AMERICAN JOURNAL OF PATHOLOGY

Soluble VEGFR-2: an antilymphangiogenic variant of VEGF receptors

(2010) Helena Pavlakovic et al.   Annals of the New York Academy of Sciences

Structural determinants of vascular endothelial growth factor-D receptor binding and specificity

(2010) V.-M. Leppanen et al.   BLOOD

Placental growth factor (PlGF) enhances breast cancer cell motility by mobilising ERK1/2 phosphorylation and cytoskeletal rearrangement

(2010) A P Taylor et al.   BRITISH JOURNAL OF CANCER

Vascular endothelial growth factor receptor-1 in human cancer

(2010) Jonathan D. Schwartz et al.   CANCER

Effective Suppression of Vascular Network Formation by Combination of Antibodies Blocking VEGFR Ligand Binding and Receptor Dimerization

(2010) Denis Tvorogov et al.   CANCER CELL

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

Integrin affinity modulation in angiogenesis

(2010) Ganapati H. Mahabeleshwar et al.   CELL CYCLE

VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis

(2010) Luqing Zhang et al.   CELL RESEARCH

Endothelial Cell Adhesion to the Extracellular Matrix Induces c-Src–Dependent VEGFR-3 Phosphorylation Without the Activation of the Receptor Intrinsic Kinase Activity

(2010) Federico Galvagni et al.   CIRCULATION RESEARCH

Neuroblastoma Progression Correlates with Downregulation of the Lymphangiogenesis Inhibitor sVEGFR-2

(2010) J. Becker et al.   CLINICAL CANCER RESEARCH

H-, N- and Kras cooperatively regulate lymphatic vessel growth by modulating VEGFR3 expression in lymphatic endothelial cells in mice

(2010) T. Ichise et al.   DEVELOPMENT

VEGF Receptor 2 Endocytic Trafficking Regulates Arterial Morphogenesis

(2010) Anthony A. Lanahan et al.   DEVELOPMENTAL CELL

VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts

(2010) Ingrid Nilsson et al.   EMBO JOURNAL

Soluble forms of VEGF receptor-1 and -2 promote vascular maturation via mural cell recruitment

(2010) Sophie Lorquet et al.   FASEB JOURNAL

Heparan Sulfate Regulates VEGF165- and VEGF121-mediated Vascular Hyperpermeability

(2010) Ding Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells

(2010) Tom T. Chen et al.   JOURNAL OF CELL BIOLOGY

Neuropilin-2 mediates VEGF-C–induced lymphatic sprouting together with VEGFR3

(2010) Yunling Xu et al.   JOURNAL OF CELL BIOLOGY

A novel intracellular isoform of VEGFR-1 activates Src and promotes cell invasion in MDA-MB-231 breast cancer cells

(2010) Belén Mezquita et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

NFAT1 Mediates Placental Growth Factor-Induced Myelomonocytic Cell Recruitment via the Induction of TNF - α

(2010) Yanping Ding et al.   JOURNAL OF IMMUNOLOGY

VEGFR-1 Signaling Regulates the Homing of Bone Marrow-Derived Cells in a Mouse Stroke Model

(2010) Heike Beck et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Expression of VEGF and Its Receptors in the Bovine Endometrium Throughout the Estrous Cycle: Effects of VEGF on Prostaglandin Production in Endometrial Cells

(2010) Yukari TASAKI et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Binding to the Extracellular Matrix and Proteolytic Processing: Two Key Mechanisms Regulating Vascular Endothelial Growth Factor Action

(2010) Napoleone Ferrara   MOLECULAR BIOLOGY OF THE CELL

S-Nitrosylation of β-Catenin by eNOS-Derived NO Promotes VEGF-Induced Endothelial Cell Permeability

(2010) Sébastien Thibeault et al.   MOLECULAR CELL

Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis

(2010) Suphansa Sawamiphak et al.   NATURE

Vascular endothelial growth factor B controls endothelial fatty acid uptake

(2010) Carolina E. Hagberg et al.   NATURE

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE

Alternate processing of Flt1 transcripts is directed by conserved cis -elements within an intronic region of FLT1 that reciprocally regulates splicing and polyadenylation

(2010) Christie P. Thomas et al.   NUCLEIC ACIDS RESEARCH

Structural determinants of growth factor binding and specificity by VEGF receptor 2

(2010) V.-M. Leppanen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling

(2010) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of angiogenesis by ETS transcription factors: Figure 1

(2009) Anna M. Randi et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Characterizing the Effects of the Juxtamembrane Domain on Vascular Endothelial Growth Factor Receptor-2 Enzymatic Activity, Autophosphorylation, and Inhibition by Axitinib

(2009) James Solowiej et al.   BIOCHEMISTRY

Apoptin, a tumor-selective killer

(2009) Marek Los et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Structure–function analysis of VEGF receptor activation and the role of coreceptors in angiogenic signaling

(2009) Felix S. Grünewald et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

(2009) John M.L. Ebos et al.   CANCER CELL

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

Dysfunctional Microvasculature as a Consequence of Shb Gene Inactivation Causes Impaired Tumor Growth

(2009) N. S. Funa et al.   CANCER RESEARCH

Transmembrane domain-mediated orientation of receptor monomers in active VEGFR-2 dimers

(2009) Debora Dell'Era Dosch et al.   FASEB JOURNAL

Structure and function of VEGF receptors

(2009) Edward Stuttfeld et al.   IUBMB LIFE

αvβ3 Integrin Limits the Contribution of Neuropilin-1 to Vascular Endothelial Growth Factor-induced Angiogenesis

(2009) Stephen D. Robinson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VEGF and inhibitors of TGF  type-I receptor kinase synergistically promote blood-vessel formation by inducing  5-integrin expression

(2009) Z. Liu et al.   JOURNAL OF CELL SCIENCE

Distinct role of PLC 3 in VEGF-mediated directional migration and vascular sprouting

(2009) R. Bhattacharya et al.   JOURNAL OF CELL SCIENCE

Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth

(2009) Romulo J C Albuquerque et al.   NATURE MEDICINE

Branching morphogenesis and antiangiogenesis candidates: tip cells lead the way

(2009) Peter Carmeliet et al.   Nature Reviews Clinical Oncology

Vascular permeability, vascular hyperpermeability and angiogenesis

(2008) Janice A. Nagy et al.   ANGIOGENESIS

Reevaluation of the Role of VEGF-B Suggests a Restricted Role in the Revascularization of the Ischemic Myocardium

(2008) Xuri Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vascular and epithelial junctions: a barrier for leucocyte migration

(2008) Sarah Garrido-Urbani et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization

(2008) H. Kawamura et al.   BLOOD

VEGFR-3 Expression Is Restricted to Blood and Lymphatic Vessels in Solid Tumors

(2008) Tatiana V. Petrova et al.   CANCER CELL

Blocking Neuropilin-2 Function Inhibits Tumor Cell Metastasis

(2008) Maresa Caunt et al.   CANCER CELL

Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy

(2008) Masuko Ushio-Fukai et al.   CANCER LETTERS

Vascular Endothelial Growth Factor (VEGF)-A165b Is a Weak In vitro Agonist for VEGF Receptor-2 Due to Lack of Coreceptor Binding and Deficient Regulation of Kinase Activity

(2008) H. Kawamura et al.   CANCER RESEARCH

Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase

(2008) Ian M. Evans et al.   CELLULAR SIGNALLING

Vascular Endothelial Growth Factor and Semaphorin Induce Neuropilin-1 Endocytosis via Separate Pathways

(2008) Anna Salikhova et al.   CIRCULATION RESEARCH

Adherens junctions

(2008) Noemi Rudini et al.   CURRENT BIOLOGY

Chondroitin sulphate-modified neuropilin 1 is expressed in human tumour cells and modulates 3D invasion in the U87MG human glioblastoma cell line through a p130Cas-mediated pathway

(2008) Paul Frankel et al.   EMBO REPORTS

Neuropilins: a versatile partner of extracellular molecules that regulate development and disease

(2008) Katarzyna Adela Uniewicz   Frontiers in Bioscience-Landmark

Inhibition of choroidal neovascularization by blocking vascular endothelial growth factor receptor tyrosine kinase

(2008) Junko Kami et al.   JAPANESE JOURNAL OF OPHTHALMOLOGY

Protein Kinase D-dependent Phosphorylation and Nuclear Export of Histone Deacetylase 5 Mediates Vascular Endothelial Growth Factor-induced Gene Expression and Angiogenesis

(2008) Chang Hoon Ha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching

(2008) Nicholas C. Kappas et al.   JOURNAL OF CELL BIOLOGY

VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF

(2008) Astrid F. Nottebaum et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Deletion of Vascular Endothelial Growth Factor C (VEGF-C) and VEGF-D Is Not Equivalent to VEGF Receptor 3 Deletion in Mouse Embryos

(2008) P. Haiko et al.   MOLECULAR AND CELLULAR BIOLOGY

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

(2008) Tuomas Tammela et al.   NATURE

Suppressed NFAT-dependent VEGFR1 expression and constitutive VEGFR2 signaling in infantile hemangioma

(2008) Masatoshi Jinnin et al.   NATURE MEDICINE

IQGAP1-Dependent Signaling Pathway Regulates Endothelial Cell Proliferation and Angiogenesis

(2008) Rosana D. Meyer et al.   PLoS One

Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7

(2008) S. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zebrafish VEGF Receptors: A Guideline to Nomenclature

(2008) Jeroen Bussmann et al.   PLoS Genetics

The Molecular Basis of VEGFR-1 Signal Transduction Pathways in Primary Human Monocytes

(2007) Vadim Tchaikovski et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY