标题
SPOP suppresses prostate cancer through regulation of CYCLIN E1 stability
作者
关键词
-
出版物
CELL DEATH AND DIFFERENTIATION
Volume -, Issue -, Pages -
出版商
Springer Nature America, Inc
发表日期
2018-09-20
DOI
10.1038/s41418-018-0198-0
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance
- (2017) Jinfang Zhang et al. NATURE
- Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4
- (2017) Xiangpeng Dai et al. NATURE MEDICINE
- Intrinsic BET inhibitor resistance in SPOP-mutated prostate cancer is mediated by BET protein stabilization and AKT–mTORC1 activation
- (2017) Pingzhao Zhang et al. NATURE MEDICINE
- Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors
- (2017) Hana Janouskova et al. NATURE MEDICINE
- Dysregulation of INF2-mediated mitochondrial fission in SPOP-mutated prostate cancer
- (2017) Xiaofeng Jin et al. PLoS Genetics
- Small-Molecule Targeting of E3 Ligase Adaptor SPOP in Kidney Cancer
- (2016) Zhong-Qiang Guo et al. CANCER CELL
- Higher‐order oligomerization promotes localization of SPOP to liquid nuclear speckles
- (2016) Melissa R Marzahn et al. EMBO JOURNAL
- SPOP-containing complex regulates SETD2 stability and H3K36me3-coupled alternative splicing
- (2016) Kun Zhu et al. NUCLEIC ACIDS RESEARCH
- Cyclin E Deregulation Promotes Loss of Specific Genomic Regions
- (2015) Leonardo K. Teixeira et al. CURRENT BIOLOGY
- SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression
- (2015) Wenjian Gan et al. MOLECULAR CELL
- SPOP Promotes Tumorigenesis by Acting as a Key Regulatory Hub in Kidney Cancer
- (2014) Guoqiang Li et al. CANCER CELL
- Androgen Receptor Is the Key Transcriptional Mediator of the Tumor Suppressor SPOP in Prostate Cancer
- (2014) C. Geng et al. CANCER RESEARCH
- The emerging role of speckle-type POZ protein (SPOP) in cancer development
- (2014) Ram-Shankar Mani DRUG DISCOVERY TODAY
- Discovery and saturation analysis of cancer genes across 21 tumour types
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- Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer
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- Similar, not the same
- (2013) Loredana Spoerri et al. CELL CYCLE
- Concurrent deletion of cyclin E1 and cyclin-dependent kinase 2 in hepatocytes inhibits DNA replication and liver regeneration in mice
- (2013) Wei Hu et al. HEPATOLOGY
- Golgi-associated RhoBTB3 targets Cyclin E for ubiquitylation and promotes cell cycle progression
- (2013) Albert Lu et al. JOURNAL OF CELL BIOLOGY
- Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover
- (2013) C. Geng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An integrated view of cyclin E function and regulation
- (2012) Ka Tat Siu et al. CELL CYCLE
- Fbw7 and Fbw7 Collaborate To Shuttle Cyclin E1 into the Nucleolus for Multiubiquitylation
- (2012) N. Bhaskaran et al. MOLECULAR AND CELLULAR BIOLOGY
- Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer
- (2012) Christopher E Barbieri et al. NATURE GENETICS
- Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1
- (2011) C Li et al. ONCOGENE
- Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases
- (2009) Min Zhuang et al. MOLECULAR CELL
- Analysis of Drosophila Segmentation Network Identifies a JNK Pathway Factor Overexpressed in Kidney Cancer
- (2009) J. Liu et al. SCIENCE
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