Article
Chemistry, Applied
Fan Xie, Bon-Jae Gu, Steven R. Saunders, Girish M. Ganjyal
Summary: The study found that the addition of high methoxyl pectin had minimal effect on the quality of corn starch extrudates, particularly showing better results in expansion ratio. Compared to low methoxyl pectin, high methoxyl pectin had a contrasting effect on the viscosity of the blends.
FOOD HYDROCOLLOIDS
(2021)
Article
Biochemistry & Molecular Biology
Ying Xin, Zhenzhen Liu, Chenhao Yang, Chen Dong, Fusheng Chen, Kunlun Liu
Summary: In this study, a PME-responsive nanocomplex was developed to stabilize a Pickering emulsion containing thyme essential oil, effectively preserving fresh-cut apples and providing an intelligent preservation strategy.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Food Science & Technology
Jiatong Li, Xiaoge Zhang, Ru Zhao, Yingcong Lu, Ce Wang, Cuina Wang
Summary: This study investigated the encapsulation and protection of quercetin using pea protein isolate (PPI) and high methoxyl pectin (HMP) complexes. Results showed that the complex at pH 5 exhibited higher binding affinity and encapsulation efficiency for quercetin. The complexing process improved the stability and antioxidant ability of quercetin, and also facilitated its sustained release in the intestinal fluid.
Article
Chemistry, Applied
Tiffany Abitbol, Ana Mijlkovic, Loredana Malafronte, Jasna S. Stevanic, Per Tomas Larsson, Patricia Lopez-Sanchez
Summary: The biotechnological applications of CNCs continue to expand due to their sustainable nature and compatibility with other materials. Hydrogels made from CNCs and pectin have potential applications as controlled release carriers and scaffolds for cell growth, with robust and self-supporting properties at solid contents below 2.5 %.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Applied
Ming-Kai Pan, Fang-Fang Zhou, Yong Liu, Jun-Hui Wang
Summary: The study showed that Na+ could induce gelation of pectin extracted from Premna microphylla Turcz, with the optimal Na+ concentration of 0.6 M for the formation of a gel with the best solid-like properties and crystallinity. The gel properties of the pectin gel would be weakened with further increase of Na+ concentration. The gelation of pectin was mainly caused by electrostatic shielding and hydrogen bonds induced by Na+.
FOOD HYDROCOLLOIDS
(2021)
Article
Chemistry, Applied
Sucheta Khubber, Kartikey Chaturvedi, Nirja Thakur, Nitya Sharma, Sudesh Kumar Yadav
Summary: Addition of low-methoxyl pectin (LMP) was found to enhance the firmness, rheology, and overall liking of low-fat set-yoghurt, while reducing whey loss. The presence of LMP increased bacterial counts, acidity, and soluble solids content in the yoghurt, contributing to higher gel strength and modulus. The microstructure analysis revealed changes in protein gel structure and cross-linking upon LMP addition, impacting the overall quality attributes of the product.
FOOD HYDROCOLLOIDS
(2021)
Article
Chemistry, Applied
Hui Li, Jiajia Rao, Bingcan Chen
Summary: Pectin modification can alter its functional properties and lead to new applications. Tyramine modified pectin exhibited improved solubility, amphiphilicity, and antioxidant activity. The gels formed by Tyr modified pectin had good viscoelasticity but reduced elasticity and strength compared to the native pectin gel.
FOOD HYDROCOLLOIDS
(2023)
Article
Chemistry, Applied
Jeong Ho Byeon, Yu-Ra Kang, Yoon Hyuk Chang
Summary: In this study, the researchers investigated the properties of gelatin/low methoxyl pectin (LMP) synbiotic microgels encapsulating Lacticaseibacillus casei (L. casei) and pectic oligosaccharides. The microgels were crosslinked and their morphology and interactions were analyzed using electron microscopy, X-ray diffraction, and Fourier transform infrared spectroscopy. The encapsulation efficiency of the microgels was high, and the double-crosslinked microgels showed better survival rates of L. casei under simulated gastrointestinal conditions, heat treatment, and storage. These findings suggest the potential use of double-crosslinked GEL/LMP synbiotic microgels for improving probiotic viability.
FOOD HYDROCOLLOIDS
(2023)
Article
Food Science & Technology
Oni Yuliarti, Esther Gusti, Jie Hong Chiang, Pei Xuan Teo, Jun Yi Ng
Summary: Two native cassava starches were isolated and characterized, showing differences in gelation behavior and physicochemical properties. Addition of low methoxyl pectin and calcium could enhance the gel strength of starch-based fruit filling, as indicated by rheological and mechanical analysis.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Food Science & Technology
Shengyu Fan, Fang Fang, Ailing Lei, Jiong Zheng, Fusheng Zhang
Summary: The addition of different salt ions affected the physicochemical and rheological properties of the LMP/CAS complex, with Ca2+ resulting in higher particle size and turbidity values, as well as changes in the secondary structure of the proteins in the complex. This study provides valuable information for the application of the LMP/CAS complex in the food industry.
Article
Chemistry, Applied
Pengpu Wang, Guoyu Sun, Pei Lu, Yanbing Liu, Yuchen Zhu, Fang Chen
Summary: This study investigated the inhibitory effect of high methoxyl apple pectin on AA formation. The results showed that temperature, pH value, pectin addition, substrate concentration, and molar ratio of Asn/Glc significantly influenced the inhibition of pectin on AA formation. The addition of pectin reduced the pH value, Glc consumption, and Schiff base abundance in the Asn/Glc model system. Heating treatment also affected the pH value, molecular weight, esterification degree, and galacturonic acid content of pectin. The degradation product of pectin competed with Glc for Asn, leading to AA reduction.
Article
Chemistry, Applied
Jiong Zheng, Nan Wang, Shan Huang, Jianquan Kan, Fusheng Zhang
Summary: The addition of HMP increased the viscosity and elasticity of starch paste, while DHPM treatment decreased these parameters. DHPM treatment improved the ordered and crystalline structures of starch-HMP mixtures, forming a compact surface that slowed down digestibility. However, intense shear force under 200 MPa DHPM disrupted the crystalline and semicrystalline structure of starch, leading to increased digestibility.
CARBOHYDRATE POLYMERS
(2021)
Article
Agriculture, Multidisciplinary
Caian He, Imca Sampers, Davy Van de Walle, Koen Dewettinck, Katleen Raes
Summary: This study utilized new low-methoxyl pectins as coating materials to encapsulate probiotics, demonstrating enhanced protection against heat shock, freeze-drying, and gastrointestinal digestion. Biofilm-forming microcapsules showed superior bacterial resistance compared to planktonic lactobacilli, highlighting their potential for improving probiotic survival.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Chemistry, Applied
Edgar Alan Cortes Morales, Ali Sedaghat Doost, Gonzalo Velazquez, Paul Van der Meeren
Summary: Lutein (LUT), a natural colorant and antioxidant found in vegetable sources, can be effectively protected and incorporated into food products using a system of WPI and pectin. The study showed that different types and ratios of pectin, as well as pH levels, can affect the stability and binding properties of LUT-loaded WPI:pectin nanocomplexes. The optimal pH condition for binding LUT to WPI was found to be pH 7.0.
FOOD HYDROCOLLOIDS
(2021)
Article
Engineering, Environmental
Javier Martinez-Sabando, Francesco Coin, Juan Carlos Raposo, Aitor Larranaga, Jorge H. Melillo, Silvina Cerveny
Summary: The study developed a novel approach to enhance the remediation capacity of pectin by crosslinking it with different agents. The results showed that dual-cross-linked pectin is a highly effective adsorbent for the simultaneous removal of both heavy metals and pharmaceutical products. This new method has the potential to significantly enhance pectin's remediation capacity, offering a promising solution for the simultaneous removal of multiple pollutants from water.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Applied
Nasreddine Benbettaieb, Odile Chambin, Ali Assifaoui, Saphwan Al-Assaf, Thomas Karbowiak, Frederic Debeaufort
FOOD HYDROCOLLOIDS
(2016)
Article
Chemistry, Physical
Uyen T. D. Huynh, Adrien Lerbret, Fabrice Neiers, Odile Chambin, Ali Assifaoui
JOURNAL OF PHYSICAL CHEMISTRY B
(2016)
Article
Engineering, Chemical
Uyen T. D. Huynh, Ali Assifaoui, Odile Chambin
JOURNAL OF FOOD ENGINEERING
(2017)
Article
Polymer Science
Pensak Jantrawut, Tanpong Chaiwarit, Kittisak Jantanasakulwong, Claire Helene Brachais, Odile Chambin
Article
Chemistry, Applied
Uyen T. D. Huynh, Odile Chambin, Aline Maire du Poset, Ali Assifaoui
CARBOHYDRATE POLYMERS
(2018)
Article
Pharmacology & Pharmacy
Rania Allouche, Sebastien Dupont, Alexandre Charriau, Patrick Gervais, Laurent Beney, Odile Chambin
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2018)
Article
Chemistry, Medicinal
Duc Hung Nguyen, Anne-Claire Mitaine-Offer, Sveva Maroso, Anna-Maria Papini, Thomas Paululat, Pierre-Simon Bellaye, Bertrand Collin, Odile Chambin, Marie-Aleth Lacaille-Dubois
Article
Chemistry, Applied
Tanpong Chaiwarit, Supuksorn Masavang, Joaquim Mahe, Sarana Sommano, Warintorn Ruksiriwanich, Claire-Helene Brachais, Odile Chambin, Pensak Jantrawut
FOOD HYDROCOLLOIDS
(2020)
Article
Biochemistry & Molecular Biology
Nasreddine Benbettaieb, Rima Mahfoudh, Sylvie Moundanga, Claire-Helene Brachais, Odile Chambin, Frederic Debeaufort
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2020)
Article
Pharmacology & Pharmacy
Audrey Raise, Sebastien Dupont, Cyril Iaconelli, Christian Caliri, Alexandre Charriau, Patrick Gervais, Odile Chambin, Laurent Beney
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2020)
Article
Plant Sciences
Duc Hung Nguyen, Anne-Claire Mitaine-Offer, Tomofumi Miyamoto, Chiaki Tanaka, Pierre-Simon Bellaye, Bertrand Collin, Odile Chambin, Marie-Aleth Lacaille-Dubois
PHYTOCHEMISTRY LETTERS
(2020)
Article
Biochemistry & Molecular Biology
Duc Hung Nguyen, Anne-Claire Mitaine-Offer, Tomofumi Miyamoto, Chiaki Tanaka, Pierre-Simon Bellaye, Bertrand Collin, Odile Chambin, Marie-Aleth Lacaille-Dubois
Summary: A phytochemical study of Cordyline fruticosa Fairchild red from Vietnam led to the isolation of fourteen steroidal glycosides, including twelve previously undescribed and two known ones. The structures of these compounds, mainly spirostanol and furostanol glycosides, were elucidated through spectroscopic analysis. The isolated compounds were evaluated for their cytotoxicity against 4T1 cell line derived from a mouse mammary gland tissue.
Article
Pharmacology & Pharmacy
Pattaraporn Panraksa, Pornchai Rachtanapun, Parichat Thipchai, Eric Lesniewska, Claire-Helene Brachais, Frederic Debeaufort, Odile Chambin, Pensak Jantrawut
Summary: With the increasing interest in eco-friendly and personalized medicines, the combination of 3D printing and biomaterials derived from agro-food wastes has been proposed. This study demonstrated the feasibility of using syringe extrusion 3D printing and carboxymethyl cellulose derived from durian rind wastes to fabricate personalized theophylline films with different structures. The findings showed that the film characteristics and release profiles could be easily modified by changing the slicing parameters, offering potential for simplified 3D printing in community pharmacies or hospitals.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
(2023)
Article
Biochemistry & Molecular Biology
Elizabeth Jacobs, Odile Chambin, Frederic Debeaufort, Nasreddine Benbettaieb
Summary: This study investigates the release and antioxidant activity kinetics of three natural antioxidants (coumarin, gallic acid, and rutin) as a binary mixture from chitosan films. The presence of rutin has an antagonistic effect on the release of gallic acid and coumarin, while the release of rutin is less affected by the other two antioxidants.
Article
Pharmacology & Pharmacy
Jan Furon, Mathieu Guerriaud, Odile Chambin, Yves Michiels
ACTUALITES PHARMACEUTIQUES
(2017)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
