Patrolling monocytes play a critical role in CX3CR1-mediated neuroprotection during excitotoxicity

CX3CR1 reduces Ly6Chigh-monocyte motility within and release from the bone marrow after chemotherapy in mice

(2013) S. Jacquelin et al.   BLOOD

Nr4a1-Dependent Ly6Clow Monocytes Monitor Endothelial Cells and Orchestrate Their Disposal

(2013) Leo M. Carlin et al.   CELL

Recruitment of Beneficial M2 Macrophages to Injured Spinal Cord Is Orchestrated by Remote Brain Choroid Plexus

(2013) Ravid Shechter et al.   IMMUNITY

Evidence for a Gender-Specific Protective Role of Innate Immune Receptors in a Model of Perinatal Brain Injury

(2013) P. M. Pimentel-Coelho et al.   JOURNAL OF NEUROSCIENCE

Busulfan Conditioning Enhances Engraftment of Hematopoietic Donor-derived Cells in the Brain Compared With Irradiation

(2013) Fiona L Wilkinson et al.   MOLECULAR THERAPY

Layer V cortical neurons require microglial support for survival during postnatal development

(2013) Masaki Ueno et al.   NATURE NEUROSCIENCE

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

(2013) Katrin Kierdorf et al.   NATURE NEUROSCIENCE

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

Positive Feedback Between PU.1 and the Cell Cycle Controls Myeloid Differentiation

(2013) H. Y. Kueh et al.   SCIENCE

The brain’s best friend: microglial neurotoxicity revisited

(2013) Sabine Hellwig et al.   Frontiers in Cellular Neuroscience

Microglia and monocyte-derived macrophages: functionally distinct populations that act in concert in CNS plasticity and repair

(2013) Anat London et al.   Frontiers in Cellular Neuroscience

Factors regulating microglia activation

(2013) Katrin Kierdorf et al.   Frontiers in Cellular Neuroscience

Real-Time In Vivo Imaging Reveals the Ability of Monocytes to Clear Vascular Amyloid Beta

(2013) Jean-Philippe Michaud et al.   Cell Reports

Long-Range Ca2+ Waves Transmit Brain-Damage Signals to Microglia

(2012) Dirk Sieger et al.   DEVELOPMENTAL CELL

Kainic Acid-Induced Neuronal Degeneration in Hippocampal Pyramidal Neurons Is Driven by Both Intrinsic and Extrinsic Factors: Analysis of FVB/N C57BL/6 Chimeras

(2012) L. Liu et al.   JOURNAL OF NEUROSCIENCE

Toll/Interleukin-1 Receptor Domain-Containing Adapter Inducing Interferon-  Mediates Microglial Phagocytosis of Degenerating Axons

(2012) S. Hosmane et al.   JOURNAL OF NEUROSCIENCE

Deficiency of the Microglial Receptor CX3CR1 Impairs Postnatal Functional Development of Thalamocortical Synapses in the Barrel Cortex

(2012) M. Hoshiko et al.   JOURNAL OF NEUROSCIENCE

Wild-type microglia arrest pathology in a mouse model of Rett syndrome

(2012) Noël C. Derecki et al.   NATURE

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

Microglia: actively surveying and shaping neuronal circuit structure and function

(2012) Hiroaki Wake et al.   TRENDS IN NEUROSCIENCES

Effects of Myeloablation, Peripheral Chimerism, and Whole-Body Irradiation on the Entry of Bone Marrow-Derived Cells into the Brain

(2011) Antoine Lampron et al.   CELL TRANSPLANTATION

NR4A1 (Nur77) Deletion Polarizes Macrophages Toward an Inflammatory Phenotype and Increases Atherosclerosis

(2011) Richard N. Hanna et al.   CIRCULATION RESEARCH

Kainic Acid-Induced Neurotoxicity: Targeting Glial Responses and Glia-Derived Cytokines

(2011) Xing-Mei Zhang et al.   Current Neuropharmacology

Lipocalin-2 Is a Chemokine Inducer in the Central Nervous System

(2011) Shinrye Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deficient CX3CR1 Signaling Promotes Recovery after Mouse Spinal Cord Injury by Limiting the Recruitment and Activation of Ly6Clo/iNOS+ Macrophages

(2011) D. J. Donnelly et al.   JOURNAL OF NEUROSCIENCE

Distinct and Non-Redundant Roles of Microglia and Myeloid Subsets in Mouse Models of Alzheimer's Disease

(2011) A. Mildner et al.   JOURNAL OF NEUROSCIENCE

CX3CR1 Deficiency Leads to Impairment of Hippocampal Cognitive Function and Synaptic Plasticity

(2011) J. T. Rogers et al.   JOURNAL OF NEUROSCIENCE

The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C− monocytes

(2011) Richard N Hanna et al.   NATURE IMMUNOLOGY

Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

(2011) Marco Prinz et al.   NATURE NEUROSCIENCE

PU.1 and C/EBP  synergistically program distinct response to NF- B activation through establishing monocyte specific enhancers

(2011) F. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

IFN-γ triggers CCR2-independent monocyte entry into the brain during systemic infection by virulent Listeria monocytogenes

(2010) Douglas A. Drevets et al.   BRAIN BEHAVIOR AND IMMUNITY

Defects in cytokine-mediated neuroprotective glial responses to excitotoxic hippocampal injury in senescence-accelerated mouse

(2010) Sanae Hasegawa-Ishii et al.   BRAIN BEHAVIOR AND IMMUNITY

Kainate and temporal lobe epilepsies: Three decades of progress

(2010) Yehezkel Ben-Ari   EPILEPSIA

Gene expression analysis of the emergence of epileptiform activity after focal injection of kainic acid into mouse hippocampus

(2010) Dario Motti et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The Transcription Factor PU.1 Controls Dendritic Cell Development and Flt3 Cytokine Receptor Expression in a Dose-Dependent Manner

(2010) Sebastian Carotta et al.   IMMUNITY

Fractalkine Attenuates Excito-neurotoxicity via Microglial Clearance of Damaged Neurons and Antioxidant Enzyme Heme Oxygenase-1 Expression

(2010) Mariko Noda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trafficking of immune cells in the central nervous system

(2010) Emma H. Wilson et al.   JOURNAL OF CLINICAL INVESTIGATION

Tickets to the brain: Role of CCR2 and CX3CR1 in myeloid cell entry in the CNS

(2010) Marco Prinz et al.   JOURNAL OF NEUROIMMUNOLOGY

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway

(2010) Eugene D Ponomarev et al.   NATURE MEDICINE

Transcriptome Analysis of the Hippocampal CA1 Pyramidal Cell Region after Kainic Acid-Induced Status Epilepticus in Juvenile Rats

(2010) Hanna B. Laurén et al.   PLoS One

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Microglial Interactions with Synapses Are Modulated by Visual Experience

(2010) Marie-Ève Tremblay et al.   PLOS BIOLOGY

Powerful beneficial effects of macrophage colony-stimulating factor on  -amyloid deposition and cognitive impairment in Alzheimer's disease

(2009) V. Boissonneault et al.   BRAIN

Resting Microglia Directly Monitor the Functional State of Synapses In Vivo and Determine the Fate of Ischemic Terminals

(2009) H. Wake et al.   JOURNAL OF NEUROSCIENCE

Taking Advantage of the Systemic Immune System to Cure Brain Diseases

(2009) V. Wee Yong et al.   NEURON

Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy

(2009) N. Cartier et al.   SCIENCE

CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival

(2008) L. Landsman et al.   BLOOD

Time-course of neuronal death in the mouse pilocarpine model of chronic epilepsy using Fluoro-Jade C staining

(2008) Lian Wang et al.   BRAIN RESEARCH

Bone-marrow-derived microglia: myth or reality?

(2008) Denis Soulet et al.   CURRENT OPINION IN PHARMACOLOGY

G-Protein-Coupled Receptor Screen Reveals a Role for Chemokine Receptor CCR5 in Suppressing Microglial Neurotoxicity

(2008) K. Gamo et al.   JOURNAL OF NEUROSCIENCE

Kainate receptors in epilepsy and excitotoxicity

(2008) P. Vincent et al.   NEUROSCIENCE