Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

Targeting Kynurenine 3-Monooxygenase (KMO): Implications for Therapy in Huntingtons Disease

(2012) Mathuravani A. Thevandavakkam et al.   CNS & Neurological Disorders-Drug Targets

Distinct and Non-Redundant Roles of Microglia and Myeloid Subsets in Mouse Models of Alzheimer's Disease

(2011) A. Mildner et al.   JOURNAL OF NEUROSCIENCE

CX3CR1 Deficiency Alters Microglial Activation and Reduces Beta-Amyloid Deposition in Two Alzheimer's Disease Mouse Models

(2010) Sungho Lee et al.   AMERICAN JOURNAL OF PATHOLOGY

Pathways linking Aβ and tau pathologies: Figure 1

(2010) Frank M. LaFerla   BIOCHEMICAL SOCIETY TRANSACTIONS

Microglia in the CNS: Immigrants from another world

(2010) Marco Prinz et al.   GLIA

Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals

(2010) Jason J. Corneveaux et al.   HUMAN MOLECULAR GENETICS

Neuroinflammatory processes in Alzheimer’s disease

(2010) Michael T. Heneka et al.   JOURNAL OF NEURAL TRANSMISSION

Novel Characterization of Monocyte-Derived Cell Populations in the Meninges and Choroid Plexus and Their Rates of Replenishment in Bone Marrow Chimeric Mice

(2010) Holly R. Chinnery et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

CX3CR1 in Microglia Regulates Brain Amyloid Deposition through Selective Protofibrillar Amyloid-  Phagocytosis

(2010) Z. Liu et al.   JOURNAL OF NEUROSCIENCE

Macrophage-mediated GDNF Delivery Protects Against Dopaminergic Neurodegeneration: A Therapeutic Strategy for Parkinson's Disease

(2010) KC Biju et al.   MOLECULAR THERAPY

The myeloid cells of the central nervous system parenchyma

(2010) Richard M. Ransohoff et al.   NATURE

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Pericytes are required for blood–brain barrier integrity during embryogenesis

(2010) Richard Daneman et al.   NATURE

Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease

(2010) Martin Fuhrmann et al.   NATURE NEUROSCIENCE

Microglia in neurodegenerative disease

(2010) V. Hugh Perry et al.   Nature Reviews Neurology

Regulation of Tau Pathology by the Microglial Fractalkine Receptor

(2010) Kiran Bhaskar et al.   NEURON

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

(2010) Robert D. Bell et al.   NEURON

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice

(2010) Noah Saederup et al.   PLoS One

Development of Monocytes, Macrophages, and Dendritic Cells

(2010) F. Geissmann et al.   SCIENCE

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Microglial Interactions with Synapses Are Modulated by Visual Experience

(2010) Marie-Ève Tremblay et al.   PLOS BIOLOGY

Microglial Physiology: Unique Stimuli, Specialized Responses

(2009) Richard M. Ransohoff et al.   Annual Review of Immunology

Inflammation in transgenic mouse models of neurodegenerative disorders

(2009) Claudia Schwab et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease

(2009) I. L. King et al.   BLOOD

CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system

(2009) Alexander Mildner et al.   BRAIN

Macrophage colony stimulating factor (M-CSF) exacerbates ALS disease in a mouse model through altered responses of microglia expressing mutant superoxide dismutase

(2009) Genevieve Gowing et al.   EXPERIMENTAL NEUROLOGY

Chemokines and Chemokine Receptors: Standing at the Crossroads of Immunobiology and Neurobiology

(2009) Richard M. Ransohoff   IMMUNITY

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia

(2009) Stefan A Grathwohl et al.   NATURE NEUROSCIENCE

Selective targeting of perivascular macrophages for clearance of  -amyloid in cerebral amyloid angiopathy

(2009) C. A. Hawkes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

(2008) Maria Björkqvist et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Rapid Microglial Response Around Amyloid Pathology after Systemic Anti-A  Antibody Administration in PDAPP Mice

(2008) J. Koenigsknecht-Talboo et al.   JOURNAL OF NEUROSCIENCE

Immune cell entry into the central nervous system: Involvement of adhesion molecules and chemokines

(2008) Britta Engelhardt   JOURNAL OF THE NEUROLOGICAL SCIENCES

Hematopoietic stem cell transplantation in patients with sporadic amyotrophic lateral sclerosis

(2008) S. H. Appel et al.   NEUROLOGY

Non-Cell-Autonomous Effects of Presenilin 1 Variants on Enrichment-Mediated Hippocampal Progenitor Cell Proliferation and Differentiation

(2008) Se Hoon Choi et al.   NEURON

Cystatin C-Cathepsin B Axis Regulates Amyloid Beta Levels and Associated Neuronal Deficits in an Animal Model of Alzheimer's Disease

(2008) Binggui Sun et al.   NEURON