Cognitive and emotional alterations in App knock-in mouse models of Aβ amyloidosis

Reduction in open field activity in the absence of memory deficits in the App NL−G−F knock-in mouse model of Alzheimer’s disease

(2018) Lauren S. Whyte et al.   BEHAVIOURAL BRAIN RESEARCH

Loss of kallikrein‐related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice

(2018) Kiwami Kidana et al.   EMBO Molecular Medicine

Review: Neuropathology and behavioural features of transgenic murine models of Alzheimer's disease

(2017) K. E. Ameen-Ali et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Lifelong behavioral and neuropathological consequences of repetitive mild traumatic brain injury

(2017) Benoit C. Mouzon et al.   Annals of Clinical and Translational Neurology

Subtle behavioral changes and increased prefrontal-hippocampal network synchronicity in APPNL−G−F mice before prominent plaque deposition

(2017) Amira Latif-Hernandez et al.   BEHAVIOURAL BRAIN RESEARCH

Chronic Repetitive Mild Traumatic Brain Injury Results in Reduced Cerebral Blood Flow, Axonal Injury, Gliosis, and Increased T-Tau and Tau Oligomers

(2016) Joseph O. Ojo et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Store-Operated Calcium Channel Complex in Postsynaptic Spines: A New Therapeutic Target for Alzheimer's Disease Treatment

(2016) Hua Zhang et al.   JOURNAL OF NEUROSCIENCE

Alzheimer's disease

(2016) Philip Scheltens et al.   LANCET

Defeating Alzheimer's disease and other dementias: a priority for European science and society

(2016) Bengt Winblad et al.   LANCET NEUROLOGY

Cognitive deficits in single App knock-in mouse models

(2016) Akira Masuda et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Age-related changes in behavior in C57BL/6J mice from young adulthood to middle age

(2016) Hirotaka Shoji et al.   Molecular Brain

Rodent models for Alzheimer’s disease drug discovery

(2015) Daniela Puzzo et al.   Expert Opinion on Drug Discovery

Neuronal Store-Operated Calcium Entry and Mushroom Spine Loss in Amyloid Precursor Protein Knock-In Mouse Model of Alzheimer's Disease

(2015) H. Zhang et al.   JOURNAL OF NEUROSCIENCE

Neuronal circuits for fear and anxiety

(2015) Philip Tovote et al.   NATURE REVIEWS NEUROSCIENCE

Loss of GPR3 reduces the amyloid plaque burden and improves memory in Alzheimer’s disease mouse models

(2015) Yunhong Huang et al.   Science Translational Medicine

Barriers to developing a valid rodent model of Alzheimer's disease: from behavioral analysis to etiological mechanisms

(2015) Darryl C. Gidyk et al.   Frontiers in Neuroscience

Dorsal Raphe Neuroinflammation Promotes Dramatic Behavioral Stress Dysregulation

(2014) A. R. Howerton et al.   JOURNAL OF NEUROSCIENCE

Chronic gliosis and behavioral deficits in mice following repetitive mild traumatic brain injury

(2014) Rebekah Mannix et al.   JOURNAL OF NEUROSURGERY

Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: interplay with cerebral blood flow

(2014) Hongmei Li et al.   Molecular Neurodegeneration

Single App knock-in mouse models of Alzheimer's disease

(2014) Takashi Saito et al.   NATURE NEUROSCIENCE

Developmental alterations in anxiety and cognitive behavior in serotonin transporter mutant mice

(2014) Yasufumi Sakakibara et al.   PSYCHOPHARMACOLOGY

Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models

(2014) Scott J. Webster et al.   Frontiers in Genetics

The contextual brain: implications for fear conditioning, extinction and psychopathology

(2013) Stephen Maren et al.   NATURE REVIEWS NEUROSCIENCE

Pioglitazone Improves Reversal Learning and Exerts Mixed Cerebrovascular Effects in a Mouse Model of Alzheimer’s Disease with Combined Amyloid-β and Cerebrovascular Pathology

(2013) Panayiota Papadopoulos et al.   PLoS One

Comprehensive behavioral characterization of an APP/PS-1 double knock-in mouse model of Alzheimer's disease

(2013) Scott J Webster et al.   Alzheimers Research & Therapy

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

The role of the serotonergic and GABA system in translational approaches in drug discovery for anxiety disorders

(2013) Jocelien D. A. Olivier et al.   Frontiers in Pharmacology

National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

(2012) Bradley T. Hyman et al.   Alzheimers & Dementia

Cognitive and non-cognitive behaviors in the triple transgenic mouse model of Alzheimer's disease expressing mutated APP, PS1, and Mapt (3xTg-AD)

(2012) Mohammed Filali et al.   BEHAVIOURAL BRAIN RESEARCH

Transgenic Mouse Models of Alzheimer Disease: Developing a Better Model as a Tool for Therapeutic Interventions

(2012) Masashi Kitazawa et al.   CURRENT PHARMACEUTICAL DESIGN

Detecting spatial memory deficits beyond blindness in tg2576 Alzheimer mice

(2012) Nour Yassine et al.   NEUROBIOLOGY OF AGING

A touch screen-automated cognitive test battery reveals impaired attention, memory abnormalities, and increased response inhibition in the TgCRND8 mouse model of Alzheimer's disease

(2012) Carola Romberg et al.   NEUROBIOLOGY OF AGING

APP transgenic mice for modelling behavioural and psychological symptoms of dementia (BPSD)

(2012) R. Lalonde et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Animal models of prefrontal-executive function.

(2011) Yogita Chudasama   BEHAVIORAL NEUROSCIENCE

Spatial learning and memory impairment and increased locomotion in a transgenic amyloid precursor protein mouse model of Alzheimer's disease

(2011) J.M. Walker et al.   BEHAVIOURAL BRAIN RESEARCH

The age of anxiety: role of animal models of anxiolytic action in drug discovery

(2011) John F Cryan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Assaying dissociable elements of behavioural inhibition and impulsivity: translational utility of animal models

(2011) Trevor Humby et al.   CURRENT OPINION IN PHARMACOLOGY

Characterization of Oligomer Formation of Amyloid-β Peptide Using a Split-luciferase Complementation Assay

(2011) Tadafumi Hashimoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Working memory, attention, and executive function in Alzheimer’s disease and frontotemporal dementia

(2010) Cheryl L. Stopford et al.   CORTEX

Assessment of spatial memory in mice

(2010) Sunita Sharma et al.   LIFE SCIENCES

APP Transgenic Mice: Their Use and Limitations

(2010) Claudia Balducci et al.   NEUROMOLECULAR MEDICINE

Pharmacological Enhancement of Memory and Executive Functioning in Laboratory Animals

(2010) Stan B Floresco et al.   NEUROPSYCHOPHARMACOLOGY

Behavioral profile of mice with impaired cognition in the elevated plus-maze due to a deficiency in neural cell adhesion molecule

(2010) M. Jürgenson et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Automated assessment of Pavlovian conditioned freezing and shock reactivity in mice using the VideoFreeze system

(2010) Stephan G. Anagnostaras   Frontiers in Behavioral Neuroscience

Visuo-spatial learning and memory deficits on the Barnes maze in the 16-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease

(2009) Timothy P. O’Leary et al.   BEHAVIOURAL BRAIN RESEARCH

Clinical, Neuropathologic, and Biochemical Profile of the Amyloid Precursor Protein I716F Mutation

(2009) Cristina Guardia-Laguarta et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Morphological alterations to neurons of the amygdala and impaired fear conditioning in a transgenic mouse model of Alzheimer's disease

(2009) Shira Knafo et al.   JOURNAL OF PATHOLOGY

Fear conditioning in frontotemporal lobar degeneration and Alzheimer's disease

(2008) M. Hoefer et al.   BRAIN

An Increase in Aβ42 in the Prefrontal Cortex is Associated with a Reversal-Learning Impairment in Alzheimers Disease Model Tg2576 APPsw Mice

(2008) Jia-Min Zhuo et al.   Current Alzheimer Research