Pioglitazone Improves Reversal Learning and Exerts Mixed Cerebrovascular Effects in a Mouse Model of Alzheimer’s Disease with Combined Amyloid-β and Cerebrovascular Pathology

Update on Cardiovascular Safety of PPARgamma Agonists and Relevance to Medicinal Chemistry and Clinical Pharmacology

(2012) Andreea Ciudin et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Age-Dependent Rescue by Simvastatin of Alzheimer's Disease Cerebrovascular and Memory Deficits

(2012) X.-K. Tong et al.   JOURNAL OF NEUROSCIENCE

The neurovascular unit in brain function and disease

(2011) C. Lecrux et al.   Acta Physiologica

Rosiglitazone inhibits vascular KATP channels and coronary vasodilation produced by isoprenaline

(2011) Lei Yu et al.   BRITISH JOURNAL OF PHARMACOLOGY

The promise of anti-inflammatory therapies for CNS injuries and diseases

(2011) Serge Rivest   Expert Review of Neurotherapeutics

Neurovascular function in Alzheimer's disease patients and experimental models

(2011) Nektaria Nicolakakis et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Impaired context reversal learning, but not cue reversal learning, in patients with amnestic mild cognitive impairment

(2011) Einat Levy-Gigi et al.   NEUROPSYCHOLOGIA

Transgenic Mice Overexpressing APP and Transforming Growth Factor-β1 Feature Cognitive and Vascular Hallmarks of Alzheimer's Disease

(2010) Brice Ongali et al.   AMERICAN JOURNAL OF PATHOLOGY

A Randomized Pilot Clinical Trial of the Safety of Pioglitazone in Treatment of Patients With Alzheimer Disease

(2010) David S. Geldmacher et al.   ARCHIVES OF NEUROLOGY

Intact Memory in TGF-β1 Transgenic Mice Featuring Chronic Cerebrovascular Deficit: Recovery with Pioglitazone

(2010) Nektaria Nicolakakis et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Predominant Enhancement of Glucose Uptake in Astrocytes versus Neurons during Activation of the Somatosensory Cortex

(2010) J. Chuquet et al.   JOURNAL OF NEUROSCIENCE

Thiazolidinedione Drugs and Cardiovascular Risks

(2010) Sanjay Kaul et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Wnt signaling activation reduces neuropathological markers in a mouse model of Alzheimer's disease

(2010) E M Toledo et al.   MOLECULAR PSYCHIATRY

Astrocytes as aide-mémoires

(2010) Mirko Santello et al.   NATURE

Neurodegeneration and the neurovascular unit

(2010) Berislav V Zlokovic   NATURE MEDICINE

The nuclear receptor PPARγ as a therapeutic target for cerebrovascular and brain dysfunction in Alzheimer's disease

(2010) Nektaria Nicolakakis   Frontiers in Aging Neuroscience

Neurovascular mechanisms and blood–brain barrier disorder in Alzheimer’s disease

(2009) Robert D. Bell et al.   ACTA NEUROPATHOLOGICA

Pioglitazone enhances pyruvate and lactate oxidation in cultured neurons but not in cultured astroglia

(2009) Yoshikane Izawa et al.   BRAIN RESEARCH

The neural correlates of naming and fluency deficits in Alzheimer's disease: an FDG-PET study

(2009) Rebecca J. Melrose et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

PIOGLITAZONE IMPROVED COGNITION IN A PILOT STUDY ON PATIENTS WITH ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT WITH DIABETES MELLITUS

(2009) Haruo Hanyu et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Efficacy of PPAR-γ agonist pioglitazone in mild Alzheimer disease

(2009) Tomohiko Sato et al.   NEUROBIOLOGY OF AGING

Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice

(2009) Xin-Kang Tong et al.   NEUROBIOLOGY OF DISEASE

Categorical and correlational analyses of baseline fluorodeoxyglucose positron emission tomography images from the Alzheimer's Disease Neuroimaging Initiative (ADNI)

(2009) Jessica B.S. Langbaum et al.   NEUROIMAGE

Astrocytes and the regulation of cerebral blood flow

(2009) Raymond C. Koehler et al.   TRENDS IN NEUROSCIENCES

Complete Rescue of Cerebrovascular Function in Aged Alzheimer's Disease Transgenic Mice by Antioxidants and Pioglitazone, a Peroxisome Proliferator-Activated Receptor   Agonist

(2008) N. Nicolakakis et al.   JOURNAL OF NEUROSCIENCE

Cerebrovascular Dysfunction in Amyloid Precursor Protein Transgenic Mice: Contribution of Soluble and Insoluble Amyloid-  Peptide, Partial Restoration via  -Secretase Inhibition

(2008) B. H. Han et al.   JOURNAL OF NEUROSCIENCE

Mechanisms Underlying Pioglitazone-Mediated Relaxation in Isolated Blood Vessel

(2008) Hidemi Nomura et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Altered navigational strategy use and visuospatial deficits in hAPP transgenic mice

(2006) Amy R. deIpolyi et al.   NEUROBIOLOGY OF AGING