High level transient production of recombinant antibodies and antibody fusion proteins in HEK293 cells

Isolation and Characterisation of a Human-Like Antibody Fragment (scFv) That Inactivates VEEV In Vitro and In Vivo

(2012) Torsten Rülker et al.   PLoS One

Optimization of a glycoengineered Pichia pastoris cultivation process for commercial antibody production

(2011) Jianxin Ye et al.   BIOTECHNOLOGY PROGRESS

Transient transfection of serum-free suspension HEK 293 cell culture for efficient production of human rFVIII

(2011) Kamilla Swiech et al.   BMC BIOTECHNOLOGY

Single-Chain Fv-Based Anti-HIV Proteins: Potential and Limitations

(2011) A. P. West et al.   JOURNAL OF VIROLOGY

Glycoengineered Pichia produced anti-HER2 is comparable to trastuzumab in preclinical study

(2011) Ningyan Zhang et al.   mAbs

A roadmap to generate renewable protein binders to the human proteome

(2011) Karen Colwill et al.   NATURE METHODS

Plant production of anti-β-glucan antibodies for immunotherapy of fungal infections in humans

(2011) Cristina Capodicasa et al.   PLANT BIOTECHNOLOGY JOURNAL

Rise and Fall of an Anti-MUC1 Specific Antibody

(2011) Holger Thie et al.   PLoS One

Minicircle-oriP-IFNγ: A Novel Targeted Gene Therapeutic System for EBV Positive Human Nasopharyngeal Carcinoma

(2011) Yufang Zuo et al.   PLoS One

Streamlining Homogeneous Glycoprotein Production for Biophysical and Structural Applications by Targeted Cell Line Development

(2011) Sonja Wilke et al.   PLoS One

Targeting CEA in Pancreas Cancer Xenografts with a Mutated scFv-Fc Antibody Fragment

(2011) Mark D Girgis et al.   EJNMMI Research

Valproic acid enhances recombinant mRNA and protein levels in transiently transfected Chinese hamster ovary cells

(2010) Sarah Wulhfard et al.   JOURNAL OF BIOTECHNOLOGY

A human scFv antibody generation pipeline for proteome research

(2010) Michael Hust et al.   JOURNAL OF BIOTECHNOLOGY

A high-throughput purification of monoclonal antibodies from glycoengineered Pichia pastoris

(2010) Youwei Jiang et al.   PROTEIN EXPRESSION AND PURIFICATION

Generating recombinant antibodies to the complete human proteome

(2010) Stefan Dübel et al.   TRENDS IN BIOTECHNOLOGY

A multi-Fc-species system for recombinant antibody production

(2009) Sandrine Moutel et al.   BMC BIOTECHNOLOGY

Improved microtitre plate production of single chain Fv fragments in Escherichia coli

(2009) Michael Hust et al.   New Biotechnology

Valproic acid: A viable alternative to sodium butyrate for enhancing protein expression in mammalian cell cultures

(2008) Gaurav Backliwal et al.   BIOTECHNOLOGY AND BIOENGINEERING

Human antibody RNase fusion protein targeting CD30+ lymphomas

(2008) C. Menzel et al.   BLOOD

Development of human antibody fragments using antibody phage display for the detection and diagnosis of Venezuelan equine encephalitis virus (VEEV)

(2008) Martina Kirsch et al.   BMC BIOTECHNOLOGY

Stable high volumetric production of glycosylated human recombinant IFNalpha2b in HEK293 cells

(2008) Martin Loignon et al.   BMC BIOTECHNOLOGY

Development of a generic transient transfection process at 100 L scale

(2008) Ola Tuvesson et al.   CYTOTECHNOLOGY

Rational vector design and multi-pathway modulation of HEK 293E cells yield recombinant antibody titers exceeding 1 g/l by transient transfection under serum-free conditions

(2008) Gaurav Backliwal et al.   NUCLEIC ACIDS RESEARCH

IMGT(R), the international ImMunoGeneTics information system(R)

(2008) M.-P. Lefranc et al.   NUCLEIC ACIDS RESEARCH

Transient expression and purification of chimeric heavy chain antibodies

(2008) Jianbing Zhang et al.   PROTEIN EXPRESSION AND PURIFICATION