Streamlining Homogeneous Glycoprotein Production for Biophysical and Structural Applications by Targeted Cell Line Development

An improved Flp deleter mouse in C57Bl/6 based on Flpo recombinase

(2010) Andrea Kranz et al.   GENESIS

Multiplexing RMCE: Versatile Extensions of the Flp-Recombinase-Mediated Cassette-Exchange Technology

(2010) Soeren Turan et al.   JOURNAL OF MOLECULAR BIOLOGY

Glycoprotein production for structure analysis with stable, glycosylation mutant CHO cell lines established by fluorescence-activated cell sorting

(2010) Sonja Wilke et al.   PROTEIN SCIENCE

Recombinant protein expression by targeting pre-selected chromosomal loci

(2009) Kristina Nehlsen et al.   BMC BIOTECHNOLOGY

Novel Tag-and-Exchange (RMCE) Strategies Generate Master Cell Clones with Predictable and Stable Transgene Expression Properties

(2009) Junhua Qiao et al.   JOURNAL OF MOLECULAR BIOLOGY

Homogeneity and persistence of transgene expression by omitting antibiotic selection in cell line isolation

(2008) W. L. Kaufman et al.   NUCLEIC ACIDS RESEARCH