Alternative oxidase: Distribution, induction, properties, structure, regulation, and functions

Functional expression of the Acanthamoeba castellanii alternative oxidase in Escherichia coli; regulation of the activity and evidence for Acaox gene function

(2014) Nina Antos-Krzeminska et al.   Biochemistry and Cell Biology

Probing the ubiquinol-binding site of recombinant Sauromatum guttatum alternative oxidase expressed in E. coli membranes through site-directed mutagenesis

(2014) Luke Young et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The rate of transcription in Arabidopsis chloroplasts depends on activity of alternative electron transfer pathway in mitochondria

(2014) Y. O. Zubo et al.   Doklady Biochemistry and Biophysics

Trypanosome Alternative Oxidase Possesses both an N-Terminal and Internal Mitochondrial Targeting Signal

(2014) VaNae Hamilton et al.   EUKARYOTIC CELL

Overexpression of ALTERNATIVE OXIDASE1a alleviates mitochondria-dependent programmed cell death induced by aluminium phytotoxicity in Arabidopsis

(2014) Jian Liu et al.   JOURNAL OF EXPERIMENTAL BOTANY

Effects of modifying alternative respiration on nitric oxide-induced virus resistance and PR1 protein accumulation

(2014) Z. Li et al.   JOURNAL OF GENERAL VIROLOGY

Knockdown of mitochondrial alternative oxidase induces the ‘stress state’ of signaling molecule pools inNicotiana tabacum,with implications for stomatal function

(2014) Marina Cvetkovska et al.   NEW PHYTOLOGIST

Presence of a plant-like proton-translocating pyrophosphatase in a scuticociliate parasite and its role as a possible drug target

(2014) NATALIA MALLO et al.   PARASITOLOGY

A Functional Antagonistic Relationship between Auxin and Mitochondrial Retrograde Signaling Regulates Alternative Oxidase1a Expression in Arabidopsis

(2014) A. Ivanova et al.   PLANT PHYSIOLOGY

Peroxisomal polyamine oxidase and NADPH-oxidase cross-talk for ROS homeostasis which affects respiration rate in Arabidopsis thaliana

(2014) Efthimios A. Andronis et al.   Frontiers in Plant Science

Unraveling the Heater: New Insights into the Structure of the Alternative Oxidase

(2013) Anthony L. Moore et al.   Annual Review of Plant Biology

The alternative oxidases: simple oxidoreductase proteins with complex functions

(2013) Luke Young et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The branched mitochondrial respiratory chain from Debaryomyces hansenii: Components and supramolecular organization

(2013) Alfredo Cabrera-Orefice et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Identification, expression, and taxonomic distribution of alternative oxidases in non-angiosperm plants

(2013) Karina Neimanis et al.   GENE

Expression of alternative oxidase in Drosophila ameliorates diverse phenotypes due to cytochrome oxidase deficiency

(2013) Kia K. Kemppainen et al.   HUMAN MOLECULAR GENETICS

Alternative Oxidase: A Mitochondrial Respiratory Pathway to Maintain Metabolic and Signaling Homeostasis during Abiotic and Biotic Stress in Plants

(2013) Greg Vanlerberghe   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Identification of duplicated and stress-inducible Aox2b gene co-expressed with Aox1 in species of the Medicago genus reveals a regulation linked to gene rearrangement in leguminous genomes

(2013) João Henrique Frota Cavalcanti et al.   JOURNAL OF PLANT PHYSIOLOGY

Analysis Tool Web Services from the EMBL-EBI

(2013) Hamish McWilliam et al.   NUCLEIC ACIDS RESEARCH

A lack of mitochondrial alternative oxidase compromises capacity to recover from severe drought stress

(2013) Jia Wang et al.   PHYSIOLOGIA PLANTARUM

The Membrane-Bound NAC Transcription Factor ANAC013 Functions in Mitochondrial Retrograde Regulation of the Oxidative Stress Response in Arabidopsis

(2013) I. De Clercq et al.   PLANT CELL

A Membrane-Bound NAC Transcription Factor, ANAC017, Mediates Mitochondrial Retrograde Signaling in Arabidopsis

(2013) S. Ng et al.   PLANT CELL

The alternative respiratory pathway mediates carboxylate synthesis in white lupin cluster roots under phosphorus deprivation

(2013) IGOR FLOREZ-SARASA et al.   PLANT CELL AND ENVIRONMENT

AtWRKY40 and AtWRKY63 Modulate the Expression of Stress-Responsive Nuclear Genes Encoding Mitochondrial and Chloroplast Proteins

(2013) O. Van Aken et al.   PLANT PHYSIOLOGY

Structure of the trypanosome cyanide-insensitive alternative oxidase

(2013) T. Shiba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence of an Alternative Oxidase Pathway for Mitochondrial Respiration in the Scuticociliate Philasterides dicentrarchi

(2013) Natalia Mallo et al.   PROTIST

Cytokinin-induced cell death is associated with elevated expression of alternative oxidase in tobacco BY-2 cells

(2013) Petr Mlejnek   PROTOPLASMA

Oxygen regulation of alternative respiration in fungus Phycomyces blakesleeanus: connection with phosphate metabolism

(2013) Marina Stanić et al.   RESEARCH IN MICROBIOLOGY

Cell Death of Rice Roots under Salt Stress May Be Mediated by Cyanide-Resistant Respiration

(2013) Hanqing Feng et al.   ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES

Alternative Oxidase Expression in the Mouse Enables Bypassing Cytochrome c Oxidase Blockade and Limits Mitochondrial ROS Overproduction

(2013) Riyad El-Khoury et al.   PLoS Genetics

An alternative respiratory pathway on Candida krusei: implications on susceptibility profile and oxidative stress

(2012) Sofia Costa-de-Oliveira et al.   FEMS YEAST RESEARCH

Alternative oxidase rescues mitochondria-mediated dopaminergic cell loss in Drosophila

(2012) Dickon M. Humphrey et al.   HUMAN MOLECULAR GENETICS

Inhibition of aconitase by nitric oxide leads to induction of the alternative oxidase and to a shift of metabolism towards biosynthesis of amino acids

(2012) Kapuganti J. Gupta et al.   JOURNAL OF EXPERIMENTAL BOTANY

Alternative oxidase 1 (Aox1) gene expression in roots of Medicago truncatula is a genotype-specific component of salt stress tolerance

(2012) Haythem Mhadhbi et al.   JOURNAL OF PLANT PHYSIOLOGY

Reprogramming of carbon metabolism by the transcriptional activators AcuK and AcuM in Aspergillus nidulans

(2012) Yumi Suzuki et al.   MOLECULAR MICROBIOLOGY

Alternative oxidase modulates leaf mitochondrial concentrations of superoxide and nitric oxide

(2012) Marina Cvetkovska et al.   NEW PHYTOLOGIST

The hemibiotrophic cacao pathogen Moniliophthora perniciosa depends on a mitochondrial alternative oxidase for biotrophic development

(2012) Daniela P. T. Thomazella et al.   NEW PHYTOLOGIST

T-REX: a web server for inferring, validating and visualizing phylogenetic trees and networks

(2012) A. Boc et al.   NUCLEIC ACIDS RESEARCH

Impact of tricyclazole and azoxystrobin on growth, sporulation and secondary infection of the rice blast fungus,Magnaporthe oryzae

(2012) Andrea Kunova et al.   PEST MANAGEMENT SCIENCE

Alternative Oxidase in Resistance to Biotic Stresses: Nicotiana attenuata AOX Contributes to Resistance to a Pathogen and a Piercing-Sucking Insect But Not Manduca sexta Larvae

(2012) L. Zhang et al.   PLANT PHYSIOLOGY

Identification of Genes Required for Alternative Oxidase Production in the Neurospora crassa Gene Knockout Library

(2012) Frank E. Nargang et al.   G3-Genes Genomes Genetics

Organization and Regulation of Mitochondrial Respiration in Plants

(2011) A. Harvey Millar et al.   Annual Review of Plant Biology

During the stationary growth phase, Yarrowia lipolytica prevents the overproduction of reactive oxygen species by activating an uncoupled mitochondrial respiratory pathway

(2011) Sergio Guerrero-Castillo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Modified expression of alternative oxidase in transgenic tomato and petunia affects the level of tomato spotted wilt virus resistance

(2011) Hao Ma et al.   BMC BIOTECHNOLOGY

Immunolocalization of an Alternative Respiratory Chain in Antonospora (Paranosema) locustae Spores: Mitosomes Retain Their Role in Microsporidial Energy Metabolism

(2011) Viacheslav V. Dolgikh et al.   EUKARYOTIC CELL

Differential expression of uncoupling mitochondrial protein and alternative oxidase in the plant response to stress

(2011) Thais Resende Silva Figueira et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Visual expression analysis of the responses of the alternative oxidase gene (aox1) to heat shock, oxidative, and osmotic stresses in conidia of citric acid-producing Aspergillus niger

(2011) Yuki Honda et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Impact of mitochondrial alternative oxidase expression on the response of Nicotiana tabacum to cold temperature

(2011) Jia Wang et al.   PHYSIOLOGIA PLANTARUM

Distinct responses of the mitochondrial respiratory chain to long- and short-term high-light environments in Arabidopsis thaliana

(2011) KEISUKE YOSHIDA et al.   PLANT CELL AND ENVIRONMENT

Identification of a Gene for Pyruvate-Insensitive Mitochondrial Alternative Oxidase Expressed in the Thermogenic Appendices in Arum maculatum

(2011) K. Ito et al.   PLANT PHYSIOLOGY

The reduction of reactive oxygen species formation by mitochondrial alternative respiration in tomato basal defense against TMV infection

(2011) Yang-Wen-Ke Liao et al.   PLANTA

Alternative Oxidase Dependent Respiration Leads to an Increased Mitochondrial Content in Two Long-Lived Mutants of the Ageing Model Podospora anserina

(2011) Christian Q. Scheckhuber et al.   PLoS One

Gene expression during activation of Paracoccidioides brasiliensis conidia

(2011) O. Hernandez et al.   YEAST

Alternative Oxidase Mediates Pathogen Resistance in Paracoccidioides brasiliensis Infection

(2011) Orville Hernández Ruiz et al.   PLoS Neglected Tropical Diseases

Plasticity of the mitoproteome to nitrogen sources (nitrate and ammonium) in Chlamydomonas reinhardtii: The logic of Aox1 gene localization

(2010) Stéphanie Gérin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Ubiquinol-binding site in the alternative oxidase: Mutagenesis reveals features important for substrate binding and inhibition

(2010) Mary S. Albury et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Purification and kinetic characterization of recombinant alternative oxidase from Trypanosoma brucei brucei

(2010) Yasutoshi Kido et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Developmental significance of cyanide-resistant respiration under stressed conditions: Experiments in Dictyostelium cells

(2010) Kei Kimura et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Involvement of an Alternative Oxidase in Oxidative Stress and Mycelium-to-Yeast Differentiation in Paracoccidioides brasiliensis

(2010) Vicente P. Martins et al.   EUKARYOTIC CELL

Deletion of the mitochondrial NADH kinase increases mitochondrial DNA stability and life span in the filamentous fungus Podospora anserina

(2010) Riyad El-Khoury et al.   EXPERIMENTAL GERONTOLOGY

Interaction of purified alternative oxidase from thermogenicArum maculatumwith pyruvate

(2010) J.E. Carré et al.   FEBS LETTERS

Mitochondria from the salt-tolerant yeast Debaryomyces hansenii (halophilic organelles?)

(2010) Alfredo Cabrera-Orefice et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Regulation of Thermogenesis in Plants: The Interaction of Alternative Oxidase and Plant Uncoupling Mitochondrial Protein

(2010) Yan Zhu et al.   Journal of Integrative Plant Biology

Proteomic and Functional Characterization of aChlamydomonas reinhardtiiMutant Lacking the Mitochondrial Alternative Oxidase 1

(2010) Grégory Mathy et al.   JOURNAL OF PROTEOME RESEARCH

The expression, function and regulation of mitochondrial alternative oxidase under biotic stresses

(2010) FENG HANQING et al.   MOLECULAR PLANT PATHOLOGY

Leaf respiration and alternative oxidase in field-grown alpine grasses respond to natural changes in temperature and light

(2010) Stephanie Y. Searle et al.   NEW PHYTOLOGIST

Seasonal variation of leaf respiration and the alternative pathway in field-grown Populus×canadensis

(2010) Stephanie Y. Searle et al.   PHYSIOLOGIA PLANTARUM

Effects of AOX1a Deficiency on Plant Growth, Gene Expression of Respiratory Components and Metabolic Profile Under Low-Nitrogen Stress in Arabidopsis thaliana

(2010) Chihiro K. Watanabe et al.   PLANT AND CELL PHYSIOLOGY

Effects of light on cyanide-resistant respiration and alternative oxidase function in Arabidopsis seedlings

(2010) DA-WEI ZHANG et al.   PLANT CELL AND ENVIRONMENT

Integrative response of plant mitochondrial electron transport chain to nitrogen source

(2010) Takushi Hachiya et al.   PLANT CELL REPORTS

Regulation of Acanthamoeba castellanii alternative oxidase activity by mutual exclusion of purine nucleotides; ATP's inhibitory effect

(2009) Andrzej M. Woyda-Ploszczyca et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

A novel functional element in the N-terminal region of Arum concinnatum alternative oxidase is indispensable for catalytic activity of the enzyme in HeLa cells

(2009) Yusuke Kakizaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mutagenesis of the Sauromatum guttatum alternative oxidase reveals features important for oxygen binding and catalysis

(2009) Paul G. Crichton et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Functional analysis reveals effects of tobacco alternative oxidase gene (NtAOX1a) on regulation of defence responses against abiotic and biotic stresses

(2009) Yi Zhang et al.   BIOSCIENCE REPORTS

Expression of the Ciona intestinalis Alternative Oxidase (AOX) in Drosophila Complements Defects in Mitochondrial Oxidative Phosphorylation

(2009) Daniel J.M. Fernandez-Ayala et al.   Cell Metabolism

Regulation of Alternative Oxidase at the Transcription Stage in Aspergillus niger Under the Conditions of Citric Acid Production

(2009) Takasumi Hattori et al.   CURRENT MICROBIOLOGY

Mutations in Two Zinc-Cluster Proteins Activate Alternative Respiratory and Gluconeogenic Pathways and Restore Senescence in Long-Lived Respiratory Mutants of Podospora anserina

(2009) C. H. Sellem et al.   GENETICS

Acanthamoeba alternative oxidase genes: Identification, characterisation and potential as antimicrobial targets

(2009) Fiona L. Henriquez et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

The alternative oxidase of Candida albicans causes reduced fluconazole susceptibility

(2009) L. Yan et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Conserved Active Site Sequences inArabidopsisPlastid Terminal Oxidase (PTOX)

(2009) Aigen Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Three Redox States ofTrypanosoma bruceiAlternative Oxidase Identified by Infrared Spectroscopy and Electrochemistry

(2009) Amandine Maréchal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative oxidase in animals: unique characteristics and taxonomic distribution

(2009) A. E. McDonald et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Stress-induced co-expression of two alternative oxidase (VuAox1 and 2b) genes in Vigna unguiculata

(2009) José Hélio Costa et al.   JOURNAL OF PLANT PHYSIOLOGY

Functional properties of the Ustilago maydis alternative oxidase under oxidative stress conditions

(2009) E. Sierra-Campos et al.   MITOCHONDRION

Induction of the AOX1D Isoform of Alternative Oxidase in A. thaliana T-DNA Insertion Lines Lacking Isoform AOX1A Is Insufficient to Optimize Photosynthesis when Treated with Antimycin A

(2009) Inga Strodtkötter et al.   Molecular Plant

Systemic Induction and Role of Mitochondrial Alternative Oxidase and Nitric Oxide in a Compatible Tomato–Tobacco mosaic virusInteraction

(2009) Li-Jun Fu et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Aoxgene structure, transcript variation and expression in plants

(2009) Alexios N. Polidoros et al.   PHYSIOLOGIA PLANTARUM

Alternative oxidase: what information can protein sequence comparisons give us?

(2009) Allison E. McDonald   PHYSIOLOGIA PLANTARUM

Alternative oxidase: a target and regulator of stress responses

(2009) Olivier Van Aken et al.   PHYSIOLOGIA PLANTARUM

Is the maintenance of homeostatic mitochondrial signaling during stress a physiological role for alternative oxidase?

(2009) Greg C. Vanlerberghe et al.   PHYSIOLOGIA PLANTARUM

Investigation of regulatory factors required for alternative oxidase production inNeurospora crassa

(2009) Michael S. Chae et al.   PHYSIOLOGIA PLANTARUM

The alternative oxidase, a tool for compensating cytochromecoxidase deficiency in human cells

(2009) Emmanuel P. Dassa et al.   PHYSIOLOGIA PLANTARUM

Towards a structural elucidation of the alternative oxidase in plants

(2009) Mary S. Albury et al.   PHYSIOLOGIA PLANTARUM

Alternative oxidase involvement inDaucus carotasomatic embryogenesis

(2009) António Miguel Frederico et al.   PHYSIOLOGIA PLANTARUM

Manipulation of alternative oxidase can influence salt tolerance inArabidopsis thaliana

(2009) Chevaun Anne Smith et al.   PHYSIOLOGIA PLANTARUM

Differential expression and co-regulation of carrotAOXgenes (Daucus carota)

(2009) Maria Doroteia Campos et al.   PHYSIOLOGIA PLANTARUM

The alternative oxidase family ofVitis viniferareveals an attractive model to study the importance of genomic design

(2009) José Hélio Costa et al.   PHYSIOLOGIA PLANTARUM

Alternative oxidase: a defence against metabolic fluctuations?

(2009) Allan G. Rasmusson et al.   PHYSIOLOGIA PLANTARUM

Study of the effects of salicylic acid on soybean mitochondrial lipids and respiratory properties using the alternative oxidase as a stress-reporter protein

(2009) Ana Rita Matos et al.   PHYSIOLOGIA PLANTARUM

Two Cys or Not Two Cys? That Is the Question; Alternative Oxidase in the Thermogenic Plant Sacred Lotus

(2009) N. Grant et al.   PLANT PHYSIOLOGY

Developmental Stage Specificity and the Role of Mitochondrial Metabolism in the Response of Arabidopsis Leaves to Prolonged Mild Osmotic Stress

(2009) A. Skirycz et al.   PLANT PHYSIOLOGY

The Transcription Factor ABI4 Is a Regulator of Mitochondrial Retrograde Expression of ALTERNATIVE OXIDASE1a

(2009) E. Giraud et al.   PLANT PHYSIOLOGY

What is critical for plant thermogenesis? Differences in mitochondrial activity and protein expression between thermogenic and non-thermogenic skunk cabbages

(2009) Yasuko Ito-Inaba et al.   PLANTA

Compelling EPR evidence that the alternative oxidase is a diiron carboxylate protein

(2008) Anthony L. Moore et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Thirty years of protein translocation into mitochondria: Unexpectedly complex and still puzzling

(2008) Dejana Mokranjac et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Identification and characterization of an alternative oxidase in the entomopathogenic fungus Metarhizium anisopliae

(2008) Daniel Uribe et al.   CANADIAN JOURNAL OF MICROBIOLOGY

Functional expression of plant alternative oxidase decreases antimycin A-induced reactive oxygen species production in human cells

(2008) Kazushige Matsukawa et al.   FEBS LETTERS

Identification of Regulatory Pathways Controlling Gene Expression of Stress-Responsive Mitochondrial Proteins in Arabidopsis

(2008) L. H.M. Ho et al.   PLANT PHYSIOLOGY

The Absence of ALTERNATIVE OXIDASE1a in Arabidopsis Results in Acute Sensitivity to Combined Light and Drought Stress

(2008) E. Giraud et al.   PLANT PHYSIOLOGY

Cross Talk in Defense Signaling

(2008) A. Koornneef et al.   PLANT PHYSIOLOGY

Restoration of electron transport without proton pumping in mammalian mitochondria

(2008) E. Perales-Clemente et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trypanosoma brucei: Differential requirement of membrane potential for import of proteins into mitochondria in two developmental stages

(2007) Shuntae Williams et al.   EXPERIMENTAL PARASITOLOGY