Prion Protein Modulates Monoaminergic Systems and Depressive-like Behavior in Mice

Age-dependent neuromuscular impairment in prion protein knockout mice

(2015) Maria Lina Massimino et al.   MUSCLE & NERVE

Behavioral and Psychiatric Symptoms in Prion Disease

(2014) Andrew Thompson et al.   AMERICAN JOURNAL OF PSYCHIATRY

The cellular prion protein counteracts cardiac oxidative stress

(2014) Filippo Zanetti et al.   CARDIOVASCULAR RESEARCH

Review of studies that have used knockout mice to assess normal function of prion protein under immunological or pathophysiological stress

(2014) Takashi Onodera et al.   MICROBIOLOGY AND IMMUNOLOGY

Monoaminergic neurotransmitter alterations in postmortem brain regions of depressed and aggressive patients with Alzheimer's disease

(2014) Yannick Vermeiren et al.   NEUROBIOLOGY OF AGING

New paradigms for treatment-resistant depression

(2013) Carlos Zarate et al.   Annals of the New York Academy of Sciences

Role of 5-HT5A receptors in the consolidation of memory

(2013) Roberto Gonzalez et al.   BEHAVIOURAL BRAIN RESEARCH

Second messenger/signal transduction pathways in major mood disorders: moving from membrane to mechanism of action, part I: major depressive disorder

(2013) Mark J. Niciu et al.   CNS SPECTRUMS

Dopamine D3 receptor as a new pharmacological target for the treatment of depression

(2013) Gian Marco Leggio et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

PrPC Controls via Protein Kinase A the Direction of Synaptic Plasticity in the Immature Hippocampus

(2013) M. D. Caiati et al.   JOURNAL OF NEUROSCIENCE

The roles of protein kinases in learning and memory

(2013) K. P. Giese et al.   LEARNING & MEMORY

Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein

(2013) Ji Won Um et al.   NEURON

Altered behavioral aspects of aged mice lacking the cellular prion protein

(2013) Maria Lina Massimino et al.   PHYSIOLOGY & BEHAVIOR

The role of prion protein in stem cell regulation

(2013) A Miranda et al.   REPRODUCTION

Effect of 5-HT5A antagonists in animal models of schizophrenia, anxiety and depression

(2012) Ferenc Kassai et al.   BEHAVIOURAL PHARMACOLOGY

Neuroimmunoendocrine Regulation of the Prion Protein in Neutrophils

(2012) Rafael M. Mariante et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Depression: an inflammatory illness?: Figure 1

(2012) Rajeev Krishnadas et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

The Native Serotonin 5-HT5A Receptor: Electrophysiological Characterization in Rodent Cortex and 5-HT1A-Mediated Compensatory Plasticity in the Knock-Out Mouse

(2012) N. M. Goodfellow et al.   JOURNAL OF NEUROSCIENCE

Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice

(2012) J H Ledo et al.   MOLECULAR PSYCHIATRY

Prion potency in stem cells biology

(2012) Marilene H. Lopes et al.   Prion

Depressive-like behaviour of mice lacking cellular prion protein

(2011) Vinicius M. Gadotti et al.   BEHAVIOURAL BRAIN RESEARCH

Allosteric function and dysfunction of the prion protein

(2011) Rafael Linden et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Unusual Dopaminergic Depletion in Variant Creutzfeldt-Jakob Disease with Early and Rapid Cognitive Decline

(2011) Eloi Magnin et al.   EUROPEAN NEUROLOGY

Antidepressant-like responses to lithium in genetically diverse mouse strains

(2011) A. Can et al.   GENES BRAIN AND BEHAVIOR

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

(2011) Anita E. Autry et al.   NATURE

Structural organization of brain-derived mammalian prions examined by hydrogen-deuterium exchange

(2011) Vytautas Smirnovas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Physiology, Signaling, and Pharmacology of Dopamine Receptors

(2011) J.-M. Beaulieu et al.   PHARMACOLOGICAL REVIEWS

Onset and Progression of Behavioral and Molecular Phenotypes in a Novel Congenic R6/2 Line Exhibiting Intergenerational CAG Repeat Stability

(2011) Randi-Michelle Cowin et al.   PLoS One

Metabotropic glutamate receptors transduce signals for neurite outgrowth after binding of the prion protein to laminin γ1 chain

(2010) Flavio H. Beraldo et al.   FASEB JOURNAL

Role of α7 Nicotinic Acetylcholine Receptor in Calcium Signaling Induced by Prion Protein Interaction with Stress-inducible Protein 1

(2010) Flavio H. Beraldo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Memory Impairment in Transgenic Alzheimer Mice Requires Cellular Prion Protein

(2010) D. A. Gimbel et al.   JOURNAL OF NEUROSCIENCE

Uncoupling the dopamine D1-D2 receptor complex exerts antidepressant-like effects

(2010) Lin Pei et al.   NATURE MEDICINE

Impaired Glucose Tolerance in Mice Lacking Cellular Prion Protein

(2010) Alexander Strom et al.   PANCREAS

Behavioral animal models of depression

(2010) Hua-Cheng Yan et al.   Neuroscience Bulletin

In vivo imaging of synaptic function in the central nervous system: II. Mental and affective disorders

(2009) Susanne Nikolaus et al.   BEHAVIOURAL BRAIN RESEARCH

Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: prominent effects of dopamine transporter deletions

(2009) Maria T.G. Perona et al.   BEHAVIOURAL PHARMACOLOGY

Prion protein: From physiology to cancer biology

(2009) Maryam Mehrpour et al.   CANCER LETTERS

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

(2009) Juha Laurén et al.   NATURE

Early dysfunction of central 5-HT system in a murine model of bovine spongiform encephalopathy

(2009) C. Vidal et al.   NEUROSCIENCE

Prions: Protein Aggregation and Infectious Diseases

(2009) Adriano Aguzzi et al.   PHYSIOLOGICAL REVIEWS

Regulation of GABAA and Glutamate Receptor Expression, Synaptic Facilitation and Long-Term Potentiation in the Hippocampus of Prion Mutant Mice

(2009) Alejandra Rangel et al.   PLoS One

Striatal [123I] FP-CIT SPECT demonstrates dopaminergic deficit in a sporadic case of Creutzfeldt-Jakob disease

(2008) M. Ragno et al.   ACTA NEUROLOGICA SCANDINAVICA

Cellular prion protein modulates defensive attention and innate fear-induced behaviour evoked in transgenic mice submitted to an agonistic encounter with the tropical coral snake Oxyrhopus guibei

(2008) Bruno Lobão-Soares et al.   BEHAVIOURAL BRAIN RESEARCH

Cellular prion protein co-localizes with nAChR β4 subunit in brain and gastrointestinal tract

(2008) S. Petrakis et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Antidepressant-like effect of the organoselenium compound ebselen in mice: Evidence for the involvement of the monoaminergic system

(2008) Thaís Posser et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Increase of monoamine oxidase-B activity in the brain of scrapie-infected hamsters

(2008) Karim Tarik Adjou et al.   NEUROCHEMISTRY INTERNATIONAL

Physiology of the Prion Protein

(2008) Rafael Linden et al.   PHYSIOLOGICAL REVIEWS

Serotoninergic regulation of emotional and behavioural control processes

(2007) Roshan Cools et al.   TRENDS IN COGNITIVE SCIENCES