Autophagy in osteoblasts is involved in mineralization and bone homeostasis

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

Suppression of Autophagy in Osteocytes Mimics Skeletal Aging

(2013) Melda Onal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parathyroid hormone–related protein protects renal tubuloepithelial cells from apoptosis by activating transcription factor Runx2

(2013) Juan A Ardura et al.   KIDNEY INTERNATIONAL

Caspase activation regulates the extracellular export of autophagic vacuoles

(2012) Isabelle Sirois et al.   Autophagy

ATP is released from autophagic vesicles to the extracellular space in a VAMP7-dependent manner

(2012) Claudio Marcelo Fader et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Maturing reticulocytes internalize plasma membrane in glycophorin A-containing vesicles that fuse with autophagosomes before exocytosis

(2012) R. E. Griffiths et al.   BLOOD

Coordinated time-dependent modulation of AMPK/Akt/mTOR signaling and autophagy controls osteogenic differentiation of human mesenchymal stem cells

(2012) Aleksandar Pantovic et al.   BONE

Bicalutamide-induced hypoxia potentiates RUNX2-mediated Bcl-2 expression resulting in apoptosis resistance

(2012) G Browne et al.   BRITISH JOURNAL OF CANCER

An overview of the regulation of bone remodelling at the cellular level

(2012) Jasreen Kular et al.   CLINICAL BIOCHEMISTRY

Loss of Nrf2 accelerates ionizing radiation-induced bone loss by upregulating RANKL

(2012) Tapasi Rana et al.   FREE RADICAL BIOLOGY AND MEDICINE

Autophagy: A new player in skeletal maintenance?

(2012) Lynne J Hocking et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee

(2012) David W Dempster et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The role of intracellular calcium phosphate in osteoblast-mediated bone apatite formation

(2012) S. Boonrungsiman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy intersections with conventional and unconventional secretion in tissue development, remodeling and inflammation

(2012) Vojo Deretic et al.   TRENDS IN CELL BIOLOGY

Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling

(2011) Jisun Lee et al.   BIOCHEMICAL JOURNAL

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

Bone Cell Autophagy Is Regulated by Environmental Factors

(2011) Adam M. Zahm et al.   CELLS TISSUES ORGANS

Autophagy Proteins Regulate the Secretory Component of Osteoclastic Bone Resorption

(2011) Carl J. DeSelm et al.   DEVELOPMENTAL CELL

Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β

(2011) Nicolas Dupont et al.   EMBO JOURNAL

Glucocorticoid dose determines osteocyte cell fate

(2011) Junjing Jia et al.   FASEB JOURNAL

Biogenesis of a novel compartment for autophagosome-mediated unconventional protein secretion

(2011) Caroline Bruns et al.   JOURNAL OF CELL BIOLOGY

Bone mineralization proceeds through intracellular calcium phosphate loaded vesicles: A cryo-electron microscopy study

(2011) Julia Mahamid et al.   JOURNAL OF STRUCTURAL BIOLOGY

Association of Oxidative Stress with Postmenopausal Osteoporosis and the Effects of Hydrogen Peroxide on Osteoclast Formation in Human Bone Marrow Cell Cultures

(2010) Ki Hyun Baek et al.   CALCIFIED TISSUE INTERNATIONAL

Autophagic pathways and metabolic stress

(2010) S. Kaushik et al.   DIABETES OBESITY & METABOLISM

From Estrogen-Centric to Aging and Oxidative Stress: A Revised Perspective of the Pathogenesis of Osteoporosis

(2010) Stavros C. Manolagas   ENDOCRINE REVIEWS

Protective effect of quercitrin against hydrogen peroxide-induced dysfunction in osteoblastic MC3T3-E1 cells

(2010) Eun Mi Choi   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Cellular and Molecular Mechanisms of Bone Remodeling

(2010) Liza J. Raggatt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathway-based genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius BMD

(2010) Lishu Zhang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Glucocorticoid-induced autophagy in osteocytes

(2010) Xuechun Xia et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Unconventional secretion of Acb1 is mediated by autophagosomes

(2010) Juan M. Duran et al.   JOURNAL OF CELL BIOLOGY

Unconventional secretion ofPichia pastorisAcb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation

(2010) Ravi Manjithaya et al.   JOURNAL OF CELL BIOLOGY

The regulation-of-autophagy pathway may influence Chinese stature variation: evidence from elder adults

(2010) Feng Pan et al.   JOURNAL OF HUMAN GENETICS

Oxidative Stress Stimulates Apoptosis and Activates NF-κB in Osteoblastic Cells via a PKCβ/p66shcSignaling Cascade: Counter Regulation by Estrogens or Androgens

(2010) Maria Almeida et al.   MOLECULAR ENDOCRINOLOGY

Neighbor of Brca1 gene (Nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 MAPK activity

(2010) C. A. Whitehouse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy: a broad role in unconventional protein secretion?

(2010) Ravi Manjithaya et al.   TRENDS IN CELL BIOLOGY

Autophagy as a basis for the health-promoting effects of vitamin D

(2010) Maria Høyer-Hansen et al.   TRENDS IN MOLECULAR MEDICINE

Autophagy contributes to degradation of Hirano bodies

(2009) Dong-Hwan Kim et al.   Autophagy

Overexpression of secreted frizzled-related protein 1 inhibits bone formation and attenuates parathyroid hormone bone anabolic effects

(2009) Wei Yao et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Runx2-mediatedbcl-2gene expression contributes to nitric oxide protection against hydrogen peroxide-induced osteoblast apoptosis

(2009) Wei-Pin Ho et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex

(2009) Yun Zhong et al.   NATURE CELL BIOLOGY

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

(2009) Kohichi Matsunaga et al.   NATURE CELL BIOLOGY

Lef1 Haploinsufficient Mice Display a Low Turnover and Low Bone Mass Phenotype in a Gender- and Age-Specific Manner

(2009) Tommy Noh et al.   PLoS One

Bone density, strength, and formation in adult cathepsin K (−/−) mice

(2008) B. Pennypacker et al.   BONE

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span

(2008) Kevin J. Pearson et al.   Cell Metabolism

To Die or Not to Die: That is the Autophagic Question

(2008) Maria Maiuri et al.   CURRENT MOLECULAR MEDICINE

Osteopontin: Role in immune regulation and stress responses

(2008) Kathryn X. Wang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Intracellular precipitation of hydroxyapatite mineral and implications for pathologic calcification

(2008) Fereshteh Azari et al.   JOURNAL OF STRUCTURAL BIOLOGY

Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG

(2008) Eisuke Itakura et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Autophagy and aging: keeping that old broom working

(2008) Ana Maria Cuervo   TRENDS IN GENETICS

Gender-related differences in oxidative stress levels among elderly patients with coronary artery disease

(2007) Cristina Vassalle et al.   FERTILITY AND STERILITY