HepaRG microencapsulated spheroids in DMSO-free culture: novel culturing approaches for enhanced xenobiotic and biosynthetic metabolism
出版年份 2014 全文链接
标题
HepaRG microencapsulated spheroids in DMSO-free culture: novel culturing approaches for enhanced xenobiotic and biosynthetic metabolism
作者
关键词
Hepatic, CYP450, 3D, Toxicology, Xenobiotic
出版物
ARCHIVES OF TOXICOLOGY
Volume 89, Issue 8, Pages 1347-1358
出版商
Springer Nature
发表日期
2014-08-08
DOI
10.1007/s00204-014-1320-9
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- 3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions
- (2014) Carsten Wenzel et al. EXPERIMENTAL CELL RESEARCH
- An imaging-based platform for high-content, quantitative evaluation of therapeutic response in 3D tumour models
- (2014) Jonathan P. Celli et al. Scientific Reports
- Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME
- (2013) Patricio Godoy et al. ARCHIVES OF TOXICOLOGY
- Impact of Alginate Composition: From Bead Mechanical Properties to Encapsulated HepG2/C3A Cell Activities for In Vivo Implantation
- (2013) Stephanie H. Capone et al. PLoS One
- 3D Organotypic Cultures of Human HepaRG Cells: A Tool for In Vitro Toxicity Studies
- (2013) Patrina Gunness et al. TOXICOLOGICAL SCIENCES
- Polarized expression of drug transporters in differentiated human hepatoma HepaRG cells
- (2013) Marc Le Vee et al. TOXICOLOGY IN VITRO
- 3D spheroid culture of hESC/hiPSC-derived hepatocyte-like cells for drug toxicity testing
- (2012) Kazuo Takayama et al. BIOMATERIALS
- Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins
- (2012) H. H. J. Gerets et al. CELL BIOLOGY AND TOXICOLOGY
- Organotypic liver culture models: Meeting current challenges in toxicity testing
- (2012) Edward L. LeCluyse et al. CRITICAL REVIEWS IN TOXICOLOGY
- Liver Progenitor Cell Line HepaRG Differentiated in a Bioartificial Liver Effectively Supplies Liver Support to Rats with Acute Liver Failure
- (2012) Geert A. A. Nibourg et al. PLoS One
- Three-Dimensional HepaRG Model As An Attractive Tool for Toxicity Testing
- (2012) Sofia B. Leite et al. TOXICOLOGICAL SCIENCES
- Diverse effects of dimethyl sulfoxide (DMSO) on the differentiation potential of human embryonic stem cells
- (2011) Rajarshi Pal et al. ARCHIVES OF TOXICOLOGY
- Hepatocyte polarization is essential for the productive entry of the hepatitis B virus
- (2011) Andreas Schulze et al. HEPATOLOGY
- Human liver cell spheroids in extended perfusion bioreactor culture for repeated-dose drug testing
- (2011) Rui M. Tostões et al. HEPATOLOGY
- The HepaRG cell line is suitable for bioartificial liver application
- (2011) Ruurdtje Hoekstra et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Alginate based 3D hydrogels as an in vitro co-culture model platform for the toxicity screening of new chemical entities
- (2011) Shih-Feng Lan et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Perfusion of 3D encapsulated hepatocytes-A synergistic effect enhancing long-term functionality in bioreactors
- (2010) Rui M. Tostões et al. BIOTECHNOLOGY AND BIOENGINEERING
- Differentiation of bone marrow-derived mesenchymal stem cells into hepatocyte-like cells in an alginate scaffold
- (2010) N. Lin et al. CELL PROLIFERATION
- A Comparison of Whole Genome Gene Expression Profiles of HepaRG Cells and HepG2 Cells to Primary Human Hepatocytes and Human Liver Tissues
- (2010) S. N. Hart et al. DRUG METABOLISM AND DISPOSITION
- Stable Expression, Activity, and Inducibility of Cytochromes P450 in Differentiated HepaRG Cells
- (2009) S. Antherieu et al. DRUG METABOLISM AND DISPOSITION
- Gradients in the Liver's Extracellular Matrix Chemistry from Periportal to Pericentral Zones: Influence on Human Hepatic Progenitors
- (2008) Randall McClelland et al. TISSUE ENGINEERING PART A
- Mature Human Hepatocytes from Ex Vivo Differentiation of Alginate-Encapsulated Hepatoblasts
- (2008) Nancy Cheng et al. TISSUE ENGINEERING PART A
- Synthetic sandwich culture of 3D hepatocyte monolayer
- (2007) Yanan Du et al. BIOMATERIALS
- Identification of metabolic fluxes in hepatic cells from transient13C-labeling experiments: Part I. Experimental observations
- (2007) Ute Hofmann et al. BIOTECHNOLOGY AND BIOENGINEERING
- Modulation of sinusoidal and canalicular elimination of bilirubin-glucuronides by rifampicin and other cholestatic drugs in a sandwich culture of rat hepatocytes
- (2007) György Lengyel et al. HEPATOLOGY RESEARCH
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now