Activation and silencing of secondary metabolites in Streptomyces albus and Streptomyces lividans after transformation with cosmids containing the thienamycin gene cluster from Streptomyces cattleya

antiSMASH 2.0—a versatile platform for genome mining of secondary metabolite producers

(2013) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

The enzymes of β-lactam biosynthesis

(2012) Refaat B. Hamed et al.   NATURAL PRODUCT REPORTS

Exploration and Mining of the Bacterial Terpenome

(2011) David E. Cane et al.   ACCOUNTS OF CHEMICAL RESEARCH

Mutational Analysis of the Thienamycin Biosynthetic Gene Cluster fromStreptomyces cattleya

(2011) Miriam Rodríguez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparative analysis of a cryptic thienamycin-like gene cluster identified in Streptomyces flavogriseus by genome mining

(2011) Gloria Blanco   ARCHIVES OF MICROBIOLOGY

Microbial metabolism of pyrazines

(2011) K. S. Rajini et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Complete Genome Sequence of Streptomyces cattleya NRRL 8057, a Producer of Antibiotics and Fluorometabolites

(2011) V. Barbe et al.   JOURNAL OF BACTERIOLOGY

The regulation of the secondary metabolism of Streptomyces: new links and experimental advances

(2011) Gilles P. van Wezel et al.   NATURAL PRODUCT REPORTS

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

(2011) Marnix H. Medema et al.   NUCLEIC ACIDS RESEARCH

Recent advances in awakening silent biosynthetic gene clusters and linking orphan clusters to natural products in microorganisms

(2010) Yi-Ming Chiang et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Fungal secondary metabolites – Strategies to activate silent gene clusters

(2010) Axel A. Brakhage et al.   FUNGAL GENETICS AND BIOLOGY

Transcriptional organization of ThnI-regulated thienamycin biosynthetic genes in Streptomyces cattleya

(2010) Miriam Rodríguez et al.   JOURNAL OF ANTIBIOTICS

Natural Products Version 2.0: Connecting Genes to Molecules

(2010) Christopher T. Walsh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Myxococcus xanthus induces actinorhodin overproduction and aerial mycelium formation by Streptomyces coelicolor

(2010) Juana Pérez et al.   Microbial Biotechnology

Characterization of rrdA, a TetR Family Protein Gene Involved in the Regulation of Secondary Metabolism in Streptomyces coelicolor

(2009) X. Ou et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Pyrazines: occurrence, formation and biodegradation

(2009) Rudolf Müller et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Strategies for the Discovery of New Natural Products by Genome Mining

(2009) Malek Zerikly et al.   CHEMBIOCHEM

Non-Heme Iron Oxygenases Generate Natural Structural Diversity in Carbapenem Antibiotics

(2009) Micah J. Bodner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Antibiotics: Natural products essential to human health

(2009) Arnold L. Demain   MEDICINAL RESEARCH REVIEWS

Evidence that Thienamycin Biosynthesis Proceeds via C-5 Epimerization: ThnE Catalyzes the Formation of (2S,5S)-trans-Carboxymethylproline

(2008) Refaat B. Hamed et al.   CHEMBIOCHEM

Renaissance in antibacterial discovery from actinomycetes

(2008) R BALTZ   CURRENT OPINION IN PHARMACOLOGY

Identification of transcriptional activators for thienamycin and cephamycin C biosynthetic genes within the thienamycin gene cluster fromStreptomyces cattleya

(2008) Miriam Rodríguez et al.   MOLECULAR MICROBIOLOGY

Four enzymes define the incorporation of coenzyme A in thienamycin biosynthesis

(2008) M. F. Freeman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA