SOD Therapeutics: Latest Insights into Their Structure-Activity Relationships and Impact on the Cellular Redox-Based Signaling Pathways
出版年份 2013 全文链接
标题
SOD Therapeutics: Latest Insights into Their Structure-Activity Relationships and Impact on the Cellular Redox-Based Signaling Pathways
作者
关键词
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出版物
ANTIOXIDANTS & REDOX SIGNALING
Volume 20, Issue 15, Pages 2372-2415
出版商
Mary Ann Liebert Inc
发表日期
2013-07-23
DOI
10.1089/ars.2012.5147
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Manganese Superoxide Dismutase-Mediated Inside-Out Signaling in HaCaT Human Keratinocytes and SKH-1 Mouse Skin
- (2014) Aaron K. Holley et al. ANTIOXIDANTS & REDOX SIGNALING
- Role of Nrf2 in Oxidative Stress and Toxicity
- (2013) Qiang Ma Annual Review of Pharmacology and Toxicology
- Mn Porphyrin Regulation of Aerobic Glycolysis: Implications on the Activation of Diabetogenic Immune Cells
- (2013) Meghan M. Delmastro-Greenwood et al. ANTIOXIDANTS & REDOX SIGNALING
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- (2013) Huaxin Sheng et al. ANTIOXIDANTS & REDOX SIGNALING
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- (2013) Patricia P. Jumbo-Lucioni et al. ANTIOXIDANTS & REDOX SIGNALING
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- (2013) Artak Tovmasyan et al. ANTIOXIDANTS & REDOX SIGNALING
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- (2013) Meghan M. Delmastro-Greenwood et al. ANTIOXIDANTS & REDOX SIGNALING
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- (2013) J. L. Welsh et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
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- (2013) M. Rawal et al. CANCER RESEARCH
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- (2013) S. Saito et al. CANCER RESEARCH
- Tissue Redox Activity as a Hallmark of Carcinogenesis: From Early to Terminal Stages of Cancer
- (2013) R. Bakalova et al. CLINICAL CANCER RESEARCH
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- (2013) Melba C Jaramillo et al. FREE RADICAL BIOLOGY AND MEDICINE
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- (2013) Jan Miljkovic et al. FREE RADICAL BIOLOGY AND MEDICINE
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- (2013) Ines Batinic-Haberle et al. FREE RADICAL BIOLOGY AND MEDICINE
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- (2013) Tin Weitner et al. FREE RADICAL BIOLOGY AND MEDICINE
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- (2013) Artak Tovmasyan et al. INORGANIC CHEMISTRY
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- (2013) Jade B. Aitken et al. INORGANIC CHEMISTRY
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- (2013) Shayne C. Gad et al. INTERNATIONAL JOURNAL OF TOXICOLOGY
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- (2013) Adi Haber et al. JOURNAL OF DIABETES AND ITS COMPLICATIONS
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- (2013) Nicole L. Day et al. JOURNAL OF NEUROTRAUMA
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- (2013) Mianzhi Gu et al. MOLECULAR MICROBIOLOGY
- Manganese Superoxide Dismutase (Sod2) and Redox-Control of Signaling Events That Drive Metastasis
- (2012) Nadine Hempel et al. Anti-Cancer Agents in Medicinal Chemistry
- Cellular Uptake and Organ Accumulation of Amphipolar Metallocorroles with Cytoprotective and Cytotoxic Properties
- (2012) Zoya Okun et al. Anti-Cancer Agents in Medicinal Chemistry
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- (2012) Julien Verrax et al. Anti-Cancer Agents in Medicinal Chemistry
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- (2012) Daniel A. Monti et al. PLoS One
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- (2012) Rebecca E. Oberley-Deegan et al. PLoS One
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- (2011) Pia López-Jornet et al. ACTA ODONTOLOGICA SCANDINAVICA
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- (2011) Mai-cang Gao et al. ACTA PHARMACOLOGICA SINICA
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- (2011) Laxmidhar Das et al. BIOSCIENCE REPORTS
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- (2011) Eduarda N. Martins et al. BRAIN RESEARCH BULLETIN
- Anti-inflammatory effects of selective glucocorticoid receptor modulators are partially dependent on up-regulation of dual specificity phosphatase 1
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- (2011) Dirk M. Maybauer et al. BURNS
- Quantitative Redox Biology: An Approach to Understand the Role of Reactive Species in Defining the Cellular Redox Environment
- (2011) Garry R. Buettner et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Factors Affecting Protein Thiol Reactivity and Specificity in Peroxide Reduction
- (2011) Gerardo Ferrer-Sueta et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Differential Cytostatic and Cytotoxic Action of Metallocorroles against Human Cancer Cells: Potential Platforms for Anticancer Drug Development
- (2011) Punnajit Lim et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(iii) N-methoxyalkylpyridylporphyrins
- (2011) Artak G. Tovmasyan et al. DALTON TRANSACTIONS
- Challenges associated with curcumin therapy in Alzheimer disease
- (2011) Abdenour Belkacemi et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics
- (2011) Ines Batinic-Haberle et al. FREE RADICAL BIOLOGY AND MEDICINE
- Lipophilic Mn Porphyrins in the Treatment of Brain Tumors
- (2011) Ines Batinic-Haberle et al. FREE RADICAL BIOLOGY AND MEDICINE
- 4-Hydroxy-2-Nonenal Mediates Aifm2 Release From Mitochondria: An Insight Into the Mechanism of Oxidative Stress Mediated Retrograde Signaling
- (2011) Sumitra Miriyala et al. FREE RADICAL BIOLOGY AND MEDICINE
- Lipophilicity of Mn(III) N-Alkylpyridylporphyrins Dominates Their Accumulation Within Mitochondria and Therefore in Vivo Efficacy: a Mouse Study
- (2011) Ivan Spasojevic et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mn(III) meso-tetrakis-(N-ethylpyridinium-2-yl) porphyrin mitigates total body irradiation-induced long-term bone marrow suppression
- (2011) Hongliang Li et al. FREE RADICAL BIOLOGY AND MEDICINE
- Cytotoxic effects of Mn(III)N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate
- (2011) Xiaodong Ye et al. FREE RADICAL RESEARCH
- Variables That Influence Cellular Uptake and Cytotoxic/Cytoprotective Effects of Macrocyclic Iron Complexes
- (2011) Adi Haber et al. INORGANIC CHEMISTRY
- Honokiol inhibits hypoxia-inducible factor-1 pathway
- (2011) Keng-li Lan et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Mitigation of radiation-induced lung injury by genistein and EUK-207
- (2011) Javed Mahmood et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Towards the mechanisms involved in the antioxidant action of MnIII [meso-tetrakis(4-N-methyl pyridinium) porphyrin] in mitochondria
- (2011) Juliana C. Araujo-Chaves et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Retooling Manganese(III) Porphyrin-Based Peroxynitrite Decomposition Catalysts for Selectivity and Oral Activity: A Potential New Strategy for Treating Chronic Pain
- (2011) Smita Rausaria et al. JOURNAL OF MEDICINAL CHEMISTRY
- Neuroprotective Efficacy from a Lipophilic Redox-Modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: Rodent Models of Ischemic Stroke and Subarachnoid Hemorrhage
- (2011) H. Sheng et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Effect of bromination on the electrochemistry, frontier orbitals, and spectroscopy of metallocorroles
- (2011) Atif Mahammed et al. JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
- Manganese(III) Complexes of Bis(hydroxyphenyl)dipyrromethenes Are Potent Orally Active Peroxynitrite Scavengers
- (2011) Smita Rausaria et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Amelioration of Renal Ischemia-Reperfusion Injury With a Novel Protective Cocktail
- (2011) Thambi Dorai et al. JOURNAL OF UROLOGY
- SOD Mimetics: A Novel Class of Androgen Receptor Inhibitors That Suppresses Castration-Resistant Growth of Prostate Cancer
- (2011) R. Thomas et al. MOLECULAR CANCER THERAPEUTICS
- ROS Signaling by NOX4 Drives Fibroblast-to-Myofibroblast Differentiation in the Diseased Prostatic Stroma
- (2011) Natalie Sampson et al. MOLECULAR ENDOCRINOLOGY
- NADPH oxidase inhibition attenuates total body irradiation-induced haematopoietic genomic instability
- (2011) S. K. Pazhanisamy et al. MUTAGENESIS
- Regional cerebral metabolism in mouse under chronic manganese exposure: Implications for Manganism
- (2011) Puneet Bagga et al. NEUROCHEMISTRY INTERNATIONAL
- Investigations into the role of inflammation in normal tissue response to irradiation
- (2011) Richard Peter Hill et al. RADIOTHERAPY AND ONCOLOGY
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- (2011) Francisco Garcia Soriano et al. SHOCK
- Acceleration of wound repair by curcumin in the excision wound of mice exposed to different doses of fractionated γ radiation
- (2011) Ganesh Chandra Jagetia et al. International Wound Journal
- Influence of glutathione levels and activity of glutathione-related enzymes in the brains of tumor-bearing mice
- (2011) Kaikai Shen et al. BioScience Trends
- Prevalence of Testosterone Deficiency After Spinal Cord Injury
- (2011) Anita Durga et al. PM&R
- Beneficial pulmonary effects of a metalloporphyrinic peroxynitrite decomposition catalyst in burn and smoke inhalation injury
- (2010) Matthias Lange et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities
- (2010) Ines Batinic-Haberle et al. AMINO ACIDS
- Superoxide Dismutase Mimics: Chemistry, Pharmacology, and Therapeutic Potential
- (2010) Ines Batinić-Haberle et al. ANTIOXIDANTS & REDOX SIGNALING
- Cellular pathways for transport and efflux of ascorbate and dehydroascorbate
- (2010) Alessandro Corti et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
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- (2010) Soon Yew Tang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2010) Henry Jay Forman et al. BIOCHEMISTRY
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- (2010) Junqiang Tian et al. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
- Low Ascorbate Levels Are Associated with Increased Hypoxia-Inducible Factor-1 Activity and an Aggressive Tumor Phenotype in Endometrial Cancer
- (2010) C. Kuiper et al. CANCER RESEARCH
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- (2010) Atif Mahammed et al. CHEMICAL COMMUNICATIONS
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- (2010) J. Du et al. CLINICAL CANCER RESEARCH
- The redoxome
- (2010) Maike Thamsen et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Accumulation of Porphyrin-based SOD Mimics in Mitochondria is Proportional to Their Lipophilicity: S. cerevisiae Study of ortho Mn(III) N-alkylpyridylporphyrins
- (2010) Ivan Spasojevic et al. FREE RADICAL BIOLOGY AND MEDICINE
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- (2010) Melba C. Jaramillo et al. FREE RADICAL BIOLOGY AND MEDICINE
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- (2010) Aekyong Kim et al. FREE RADICAL BIOLOGY AND MEDICINE
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- (2010) Benjamin Gauter-Fleckenstein et al. FREE RADICAL BIOLOGY AND MEDICINE
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- (2010) Ivan Spasojevic et al. FREE RADICAL RESEARCH
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- (2009) Khairul I. Ansari et al. DALTON TRANSACTIONS
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- (2009) Meital Eckshtain et al. DALTON TRANSACTIONS
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- (2009) Julianne M. Pollard et al. FREE RADICAL BIOLOGY AND MEDICINE
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- (2009) Hongying Zheng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2009) Ivan Kos et al. JOURNAL OF MEDICINAL CHEMISTRY
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- (2009) Júlio S. Rebouças et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
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- (2009) Jimmie Colon et al. Nanomedicine-Nanotechnology Biology and Medicine
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- (2009) Hee Young Kim et al. NEUROREPORT
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- (2009) T. Doyle et al. NEUROSCIENCE
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- (2009) Andrea E. Para et al. RADIOTHERAPY AND ONCOLOGY
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- (2009) M. G. Vander Heiden et al. SCIENCE
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- (2008) Adi Haber et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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- (2008) Miloš R. Filipović et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Phase I clinical trial of i.v. ascorbic acid in advanced malignancy
- (2008) L. J. Hoffer et al. ANNALS OF ONCOLOGY
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- (2008) Vani Nilakantan et al. APOPTOSIS
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- (2008) Júlio S. Rebouças et al. DALTON TRANSACTIONS
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- (2008) Júlio S. Rebouças et al. FREE RADICAL BIOLOGY AND MEDICINE
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- (2008) Ivan Spasojević et al. FREE RADICAL BIOLOGY AND MEDICINE
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- (2008) Ines Batinić-Haberle et al. FREE RADICAL BIOLOGY AND MEDICINE
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