Mn Porphyrin Regulation of Aerobic Glycolysis: Implications on the Activation of Diabetogenic Immune Cells

Effects of Metalloporphyrins on Reducing Inflammation and Autoimmunity

(2013) Meghan M. Delmastro-Greenwood et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox regulation of protein kinases

(2013) Aoife Corcoran et al.   FEBS Journal

Transcriptional Amplification in Tumor Cells with Elevated c-Myc

(2012) Charles Y. Lin et al.   CELL

Modulation of Redox Balance Leaves Murine Diabetogenic TH1 T Cells "LAG-3-ing" Behind

(2012) M. M. Delmastro et al.   DIABETES

Manganese Porphyrin, MnTE-2-PyP5+, Acts as a Pro-Oxidant to Potentiate Glucocorticoid-Induced Apoptosis in Lymphoma Cells

(2012) Melba C. Jaramillo et al.   FREE RADICAL BIOLOGY AND MEDICINE

NAD+-dependent Sirtuin 1 and 6 Proteins Coordinate a Switch from Glucose to Fatty Acid Oxidation during the Acute Inflammatory Response

(2012) Tie Fu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel Steroid Inhibitors of Glucose 6-Phosphate Dehydrogenase

(2012) Niall M. Hamilton et al.   JOURNAL OF MEDICINAL CHEMISTRY

Neuroprotective Effect of Natural Products Against Alzheimer’s Disease

(2012) Musthafa M. Essa et al.   NEUROCHEMICAL RESEARCH

Targeting metabolism for cancer treatment and prevention: metformin, an old drug with multi-faceted effects

(2012) M A Pierotti et al.   ONCOGENE

Modulation of the Pentose Phosphate Pathway Induces Endodermal Differentiation in Embryonic Stem Cells

(2012) Genesia Manganelli et al.   PLoS One

Epigallocatechin-3-Gallate Ameliorates Experimental Autoimmune Encephalomyelitis by Altering Balance among CD4+ T-Cell Subsets

(2011) Junpeng Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

Resveratrol modulates murine collagen-induced arthritis by inhibiting Th17 and B-cell function

(2011) Gao Xuzhu et al.   ANNALS OF THE RHEUMATIC DISEASES

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

(2011) Sophia Y. Lunt et al.   Annual Review of Cell and Developmental Biology

Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

(2011) Eric V. Dang et al.   CELL

Oxidative Stress and Redox Modulation Potential in Type 1 Diabetes

(2011) Meghan M. Delmastro et al.   Clinical & Developmental Immunology

A multivalent vaccine for type 1 diabetes skews T cell subsets to Th2 phenotype in NOD mice

(2011) Ming S. Lin et al.   IMMUNOLOGIC RESEARCH

Impaired Mitochondrial Respiratory Functions and Oxidative Stress in Streptozotocin-Induced Diabetic Rats

(2011) Haider Raza et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antioxidant α-tocopherol checks lymphoma promotion via regulation of expression of protein kinase C-α and c-Myc genes and glycolytic metabolism

(2011) Renu Sharma et al.   LEUKEMIA & LYMPHOMA

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

(2011) Greg M Delgoffe et al.   NATURE IMMUNOLOGY

mTOR couples cellular nutrient sensing to organismal metabolic homeostasis

(2011) Jessica J. Howell et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Inhibition of fatty acid metabolism ameliorates disease activity in an animal model of multiple sclerosis

(2011) Leah P. Shriver et al.   Scientific Reports

Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities

(2010) Ines Batinic-Haberle et al.   AMINO ACIDS

Superoxide Dismutase Mimics: Chemistry, Pharmacology, and Therapeutic Potential

(2010) Ines Batinić-Haberle et al.   ANTIOXIDANTS & REDOX SIGNALING

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation

(2010) C. M. Krawczyk et al.   BLOOD

Metabolism in T cell activation and differentiation

(2010) Erika L Pearce   CURRENT OPINION IN IMMUNOLOGY

3-Bromopyruvate: A New Targeted Antiglycolytic Agent and a Promise for Cancer Therapy

(2010) S. Ganapathy-Kanniappan et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Redox Modulation Protects Islets From Transplant-Related Injury

(2010) M. M. Sklavos et al.   DIABETES

Elevated mitochondrial superoxide disrupts normal T cell development, impairing adaptive immune responses to an influenza challenge

(2010) Adam J. Case et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hepatocyte Growth Factor Modulates Interleukin-6 Production in Bone Marrow Derived Macrophages: Implications for Inflammatory Mediated Diseases

(2010) Gina M. Coudriet et al.   PLoS One

MYC-Induced Cancer Cell Energy Metabolism and Therapeutic Opportunities

(2009) C. V. Dang et al.   CLINICAL CANCER RESEARCH

Thymus-specific deletion of insulin induces autoimmune diabetes

(2009) Yong Fan et al.   EMBO JOURNAL

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

(2009) C. Selman et al.   SCIENCE

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Role of Nrf1 in antioxidant response element-mediated gene expression and beyond

(2009) Madhurima Biswas et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Oxidative stress: the vulnerable β-cell

(2008) Sigurd Lenzen   BIOCHEMICAL SOCIETY TRANSACTIONS

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

Malonyl CoenzymeA Decarboxylase Regulates Lipid and Glucose Metabolism in Human Skeletal Muscle

(2008) K. Bouzakri et al.   DIABETES

Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells

(2008) Candace M. Cham et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Redox modulation inhibits CD8 T cell effector function

(2008) Martha M. Sklavos et al.   FREE RADICAL BIOLOGY AND MEDICINE

Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival

(2008) Nancie J. MacIver et al.   JOURNAL OF LEUKOCYTE BIOLOGY