An Anti-C1s Monoclonal, TNT003, Inhibits Complement Activation Induced by Antibodies Against HLA
出版年份 2015 全文链接
标题
An Anti-C1s Monoclonal, TNT003, Inhibits Complement Activation Induced by Antibodies Against HLA
作者
关键词
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出版物
AMERICAN JOURNAL OF TRANSPLANTATION
Volume 15, Issue 8, Pages 2037-2049
出版商
Wiley
发表日期
2015-04-23
DOI
10.1111/ajt.13273
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Time-Dependent Specificity of Immunopathologic (C4d-CD68) and Histologic Criteria of Antibody-Mediated Rejection for Donor-Specific Antibodies and Allograft Dysfunction in Heart Transplantation
- (2015) Patrick Yerly et al. TRANSPLANTATION
- The perfect storm: HLA antibodies, complement, FcγRs, and endothelium in transplant rejection
- (2015) Kimberly A. Thomas et al. TRENDS IN MOLECULAR MEDICINE
- Banff 2013 Meeting Report: Inclusion of C4d-Negative Antibody-Mediated Rejection and Antibody-Associated Arterial Lesions
- (2014) M. Haas et al. AMERICAN JOURNAL OF TRANSPLANTATION
- TNT003, an inhibitor of the serine protease C1s, prevents complement activation induced by cold agglutinins
- (2014) J. Shi et al. BLOOD
- Recent trials in immunosuppression and their consequences for current therapy
- (2014) Mariana Wohlfahrtova et al. Current Opinion in Organ Transplantation
- Immunosuppression following heart transplantation: prospects and challenges
- (2014) David H Chang et al. Immunotherapy
- Pre-transplant donor HLA-specific antibodies: Characteristics causing detrimental effects on survival after lung transplantation
- (2014) John D. Smith et al. JOURNAL OF HEART AND LUNG TRANSPLANTATION
- De novo donor HLA-specific antibodies predict development of bronchiolitis obliterans syndrome after lung transplantation
- (2014) Shahideh Safavi et al. JOURNAL OF HEART AND LUNG TRANSPLANTATION
- Anti-MHC Class I Antibody Activation of Proliferation and Survival Signaling in Murine Cardiac Allografts
- (2014) P. T. Jindra et al. JOURNAL OF IMMUNOLOGY
- Detection of C3d-Binding Donor-Specific Anti-HLA Antibodies at Diagnosis of Humoral Rejection Predicts Renal Graft Loss
- (2014) A. Sicard et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Complement Is Activated by IgG Hexamers Assembled at the Cell Surface
- (2014) C. A. Diebolder et al. SCIENCE
- Antibody-mediated rejection despite inhibition of terminal complement
- (2014) Andrew Bentall et al. TRANSPLANT INTERNATIONAL
- Eculizumab and Splenectomy as Salvage Therapy for Severe Antibody-Mediated Rejection After HLA–Incompatible Kidney Transplantation
- (2014) Babak J. Orandi et al. TRANSPLANTATION
- Deciphering Complement Interference in Anti–Human Leukocyte Antigen Antibody Detection With Flow Beads Assays
- (2014) Jonathan Visentin et al. TRANSPLANTATION
- Report of the Inefficacy of Eculizumab in Two Cases of Severe Antibody-Mediated Rejection of Renal Grafts
- (2014) Maren Burbach et al. TRANSPLANTATION
- Complement modulation in solid-organ transplantation
- (2014) Maxime Touzot et al. Transplantation Reviews
- Immune Cell-Derived C3a and C5a Costimulate Human T Cell Alloimmunity
- (2013) P. Cravedi et al. AMERICAN JOURNAL OF TRANSPLANTATION
- De NovoDonor-Specific HLA Antibodies Decrease Patient and Graft Survival in Liver Transplant Recipients
- (2013) H. Kaneku et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Alloantibody and Complement Promote T Cell–Mediated Cardiac Allograft Vasculopathy Through Noncanonical Nuclear Factor-κB Signaling in Endothelial Cells
- (2013) Dan Jane-wit et al. CIRCULATION
- The use of eculizumab in renal transplantation
- (2013) A. Nicholas R. Barnett et al. CLINICAL TRANSPLANTATION
- Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells
- (2013) Wing-hong Kwan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The 2013 International Society for Heart and Lung Transplantation Working Formulation for the standardization of nomenclature in the pathologic diagnosis of antibody-mediated rejection in heart transplantation
- (2013) Gerald J. Berry et al. JOURNAL OF HEART AND LUNG TRANSPLANTATION
- HLA Class I Antibodies Trigger Increased Adherence of Monocytes to Endothelial Cells by Eliciting an Increase in Endothelial P-Selectin and, Depending on Subclass, by Engaging Fc Rs
- (2013) N. M. Valenzuela et al. JOURNAL OF IMMUNOLOGY
- Complement-Binding Anti-HLA Antibodies and Kidney-Allograft Survival
- (2013) Alexandre Loupy et al. NEW ENGLAND JOURNAL OF MEDICINE
- Plasmapheresis-resistant acute humoral rejection successfully treated with anti-C5 antibody
- (2013) Giulia Ghirardo et al. PEDIATRIC TRANSPLANTATION
- Anaphylatoxins in organ transplantation
- (2013) Ke Li et al. SEMINARS IN IMMUNOLOGY
- Complement Regulation of T-Cell Alloimmunity
- (2013) Paolo Cravedi et al. SEMINARS IN NEPHROLOGY
- The Role of Immunoglobulin-G Subclasses and C1q in De Novo HLA-DQ Donor-Specific Antibody Kidney Transplantation Outcomes
- (2013) Maria Cecilia S. Freitas et al. TRANSPLANTATION
- Systematic Comparison of Four Cell- and Luminex-Based Methods for Assessment of Complement-Activating HLA Antibodies
- (2013) Nils Lachmann et al. TRANSPLANTATION
- HLA class I-mediated stress fiber formation requires ERK1/2 activation in the absence of an increase in intracellular Ca2+ in human aortic endothelial cells
- (2012) Mary E. Ziegler et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Blockade of P-Selectin Is Sufficient to Reduce MHC I Antibody-Elicited Monocyte RecruitmentIn VitroandIn Vivo
- (2012) N. M. Valenzuela et al. AMERICAN JOURNAL OF TRANSPLANTATION
- New approaches for detecting complement-fixing antibodies
- (2012) Dolly B. Tyan Current Opinion in Organ Transplantation
- Role of complement and NK cells in antibody mediated rejection
- (2012) Takurin Akiyoshi et al. HUMAN IMMUNOLOGY
- Morphologic and immunohistochemical findings in antibody-mediated rejection of the cardiac allograft
- (2012) Gregory A. Fishbein et al. HUMAN IMMUNOLOGY
- Role of complement and perspectives for intervention in transplantation
- (2012) Gang Chen et al. IMMUNOBIOLOGY
- The role of therapeutic apheresis in the treatment of acute antibody-mediated kidney rejection
- (2012) Tahmeena Ahmed et al. JOURNAL OF CLINICAL APHERESIS
- Treatment of hyperacute antibody-mediated lung allograft rejection with eculizumab
- (2012) Kyle L. Dawson et al. JOURNAL OF HEART AND LUNG TRANSPLANTATION
- Persistent strong anti-HLA antibody at high titer is complement binding and associated with increased risk of antibody-mediated rejection in heart transplant recipients
- (2012) Adriana Zeevi et al. JOURNAL OF HEART AND LUNG TRANSPLANTATION
- Donor-specific human leukocyte antigen antibodies of the immunoglobulin G3 subclass are associated with Chronic rejection and graft loss after liver transplantation
- (2012) Hugo Kaneku et al. LIVER TRANSPLANTATION
- Absence of signaling into CD4+ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3+ regulatory T cells
- (2012) Michael G Strainic et al. NATURE IMMUNOLOGY
- The role of complement in antibody-mediated rejection in kidney transplantation
- (2012) Mark D. Stegall et al. Nature Reviews Nephrology
- Detection of complement-fixing and non-fixing antibodies specific for endothelial precursor cells and lymphocytes using flow cytometry
- (2012) A. AlMahri et al. TISSUE ANTIGENS
- Solid phase detection of C4d-fixing HLA antibodies to predict rejection in high immunological risk kidney transplant recipients
- (2012) Gregor Bartel et al. TRANSPLANT INTERNATIONAL
- Guidelines for the Diagnosis of Antibody-Mediated Rejection in Pancreas Allografts-Updated Banff Grading Schema
- (2011) C. B. Drachenberg et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Terminal Complement Inhibition Decreases Antibody-Mediated Rejection in Sensitized Renal Transplant Recipients
- (2011) M. D. Stegall et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Modifiers of complement activation for prevention of antibody-mediated injury to allografts
- (2011) Peter D. Hughes et al. Current Opinion in Organ Transplantation
- Regulation of immunity and inflammation by intravenous immunoglobulin: relevance to solid organ transplantation
- (2011) Stanley C Jordan et al. Expert Review of Clinical Immunology
- Novel C1q assay reveals a clinically relevant subset of human leukocyte antigen antibodies independent of immunoglobulin G strength on single antigen beads
- (2011) G. Chen et al. HUMAN IMMUNOLOGY
- Report from a consensus conference on antibody-mediated rejection in heart transplantation
- (2011) Jon Kobashigawa et al. JOURNAL OF HEART AND LUNG TRANSPLANTATION
- The ISHLT working formulation for pathologic diagnosis of antibody-mediated rejection in heart transplantation: Evolution and current status (2005–2011)
- (2011) Gerald J. Berry et al. JOURNAL OF HEART AND LUNG TRANSPLANTATION
- Complement-fixing donor-specific antibodies identified by a novel C1q assay are associated with allograft loss
- (2011) Scott M. Sutherland et al. PEDIATRIC TRANSPLANTATION
- Pre- and posttransplantation allosensitization in heart allograft recipients: Major impact of de novo alloantibody production on allograft survival
- (2010) Eric K. Ho et al. HUMAN IMMUNOLOGY
- Controversies in defining cardiac antibody-mediated rejection: Need for updated criteria
- (2010) Abdallah G. Kfoury et al. JOURNAL OF HEART AND LUNG TRANSPLANTATION
- Clinical usefulness of a novel C1q assay to detect immunoglobulin G antibodies capable of fixing complement in sensitized pediatric heart transplant patients
- (2010) Clifford Chin et al. JOURNAL OF HEART AND LUNG TRANSPLANTATION
- C1 inhibitor, a multi-functional serine protease inhibitor
- (2010) Fengxin Lu et al. THROMBOSIS AND HAEMOSTASIS
- C1q-Fixing Human Leukocyte Antigen Antibodies Are Specific for Predicting Transplant Glomerulopathy and Late Graft Failure After Kidney Transplantation
- (2010) Julie M. Yabu et al. TRANSPLANTATION
- Solid phase assays for HLA antibody detection in clinical transplantation
- (2009) Brian D Tait CURRENT OPINION IN IMMUNOLOGY
- Clinical relevance of complement-fixing antibodies in cardiac transplantation
- (2009) Marlene L. Rose et al. HUMAN IMMUNOLOGY
- Mechanisms of complement activation, C4d deposition, and their contribution to the pathogenesis of antibody-mediated rejection
- (2009) Kazunori Murata et al. Transplantation Reviews
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