标题
Hydrogen Tunneling Links Protein Dynamics to Enzyme Catalysis
作者
关键词
-
出版物
Annual Review of Biochemistry
Volume 82, Issue 1, Pages 471-496
出版商
Annual Reviews
发表日期
2013-06-08
DOI
10.1146/annurev-biochem-051710-133623
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Identification of a Long-range Protein Network That Modulates Active Site Dynamics in Extremophilic Alcohol Dehydrogenases
- (2013) Zachary D. Nagel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Active Site Hydrophobic Residues Impact Hydrogen Tunneling Differently in a Thermophilic Alcohol Dehydrogenase at Optimal versus Nonoptimal Temperatures
- (2012) Zachary D. Nagel et al. BIOCHEMISTRY
- Hydrogen Donor–Acceptor Fluctuations from Kinetic Isotope Effects: A Phenomenological Model
- (2012) Daniel Roston et al. BIOCHEMISTRY
- Momentum Distribution as a Fingerprint of Quantum Delocalization in Enzymatic Reactions: Open-Chain Path-Integral Simulations of Model Systems and the Hydride Transfer in Dihydrofolate Reductase
- (2012) Hamutal Engel et al. Journal of Chemical Theory and Computation
- Pressure Effects on Enzyme-Catalyzed Quantum Tunneling Events Arise from Protein-Specific Structural and Dynamic Changes
- (2012) Sam Hay et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Barrier crossing in dihydrofolate reductase does not involve a rate-promoting vibration
- (2012) Mariangela Dametto et al. MOLECULAR PHYSICS
- Good vibrations in enzyme-catalysed reactions
- (2012) Sam Hay et al. Nature Chemistry
- Taking Ockham's razor to enzyme dynamics and catalysis
- (2012) David R. Glowacki et al. Nature Chemistry
- Agonism/antagonism switching in allosteric ensembles
- (2012) H. N. Motlagh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enzymes in Coherent Motion
- (2012) H. P. Lu SCIENCE
- How Does Pressure Affect Barrier Compression and Isotope Effects in an Enzymatic Hydrogen Tunneling Reaction?
- (2011) Linus O. Johannissen et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Comparative Hydrogen–Deuterium Exchange for a Mesophilic vs Thermophilic Dihydrofolate Reductase at 25 °C: Identification of a Single Active Site Region with Enhanced Flexibility in the Mesophilic Protein
- (2011) Olayinka A. Oyeyemi et al. BIOCHEMISTRY
- Direct Evidence for Methyl Group Coordination by Carbon-Oxygen Hydrogen Bonds in the Lysine Methyltransferase SET7/9
- (2011) Scott Horowitz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Promoting Vibration in Human Heart Lactate Dehydrogenase Is a Preferred Vibrational Channel
- (2011) Ardy Davarifar et al. JOURNAL OF PHYSICAL CHEMISTRY B
- 3-Picolyl Azide Adenine Dinucleotide as a Probe of Femtosecond to Picosecond Enzyme Dynamics
- (2011) Samrat Dutta et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Protein Dynamics and Enzymatic Chemical Barrier Passage
- (2011) Dimitri Antoniou et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Hydrogen Tunneling Steps in Cyclooxygenase-2 Catalysis
- (2011) Husain H. Danish et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Enzymatic Methyl Transfer: Role of an Active Site Residue in Generating Active Site Compaction That Correlates with Catalytic Efficiency
- (2011) Jianyu Zhang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Effects of the Donor–Acceptor Distance and Dynamics on Hydride Tunneling in the Dihydrofolate Reductase Catalyzed Reaction
- (2011) Vanja Stojković et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- ExMS: Data Analysis for HX-MS Experiments
- (2011) Zhong-Yuan Kan et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Impaired protein conformational landscapes as revealed in anomalous Arrhenius prefactors
- (2011) Z. D. Nagel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Converting structural information into an allosteric-energy-based picture for elongation factor Tu activation by the ribosome
- (2011) A. J. Adamczyk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions
- (2011) A. J. Adamczyk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Femtosecond dynamics coupled to chemical barrier crossing in a Born-Oppenheimer enzyme
- (2011) R. G. Silva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dynamics and dissipation in enzyme catalysis
- (2011) N. Boekelheide et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Dynamic Knockout Reveals That Conformational Fluctuations Influence the Chemical Step of Enzyme Catalysis
- (2011) G. Bhabha et al. SCIENCE
- Design strategies for engineering selectivity in bio-inspired heterogeneous catalysts
- (2011) David J. Xuereb et al. Catalysis Science & Technology
- The importance of developing metal complexes with pronounced catalase-like activity
- (2011) Atif Mahammed et al. Catalysis Science & Technology
- Mimicking nature's strategies for the design of nanocatalysts
- (2011) Rohit Bhandari et al. Catalysis Science & Technology
- Update 1 of: Tunneling and Dynamics in Enzymatic Hydride Transfer
- (2010) Zachary D. Nagel et al. CHEMICAL REVIEWS
- Impact of Distal Mutation on Hydrogen Transfer Interface and Substrate Conformation in Soybean Lipoxygenase
- (2010) Sarah J. Edwards et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Direct Analysis of Donor−Acceptor Distance and Relationship to Isotope Effects and the Force Constant for Barrier Compression in Enzymatic H-Tunneling Reactions
- (2010) Christopher R. Pudney et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- An Active-Site Phenylalanine Directs Substrate Binding and C−H Cleavage in the α-Ketoglutarate-Dependent Dioxygenase TauD
- (2010) Kevin P. McCusker et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The role of conformational entropy in molecular recognition by calmodulin
- (2010) Michael S Marlow et al. Nature Chemical Biology
- Seeing the forest for the trees: fluorescence studies of single enzymes in the context of ensemble experiments
- (2010) Yan-Wen Tan et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- Temperature dependence of protein motions in a thermophilic dihydrofolate reductase and its relationship to catalytic efficiency
- (2010) O. A. Oyeyemi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Elusive transition state of alcohol dehydrogenase unveiled
- (2010) D. Roston et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Millisecond timescale fluctuations in dihydrofolate reductase are exquisitely sensitive to the bound ligands
- (2010) D. D. Boehr et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characterizing the dynamics of functionally relevant complexes of formate dehydrogenase
- (2010) J. N. Bandaria et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effect of a conservative mutation of an active site residue involved in substrate binding on the hydride tunneling reaction catalyzed by choline oxidase
- (2009) Osbourne Quaye et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- An integrated model for enzyme catalysis emerges from studies of hydrogen tunneling
- (2009) Judith P. Klinman CHEMICAL PHYSICS LETTERS
- Enzymatic tunneling and kinetic isotope effects: chemistry at the crossroads
- (2009) Arundhuti Sen et al. JOURNAL OF PHYSICAL ORGANIC CHEMISTRY
- Evidence To Support the Hypothesis That Promoting Vibrations Enhance the Rate of an Enzyme Catalyzed H-Tunneling Reaction
- (2009) Christopher R Pudney et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Functionally Important Conformations of the Met20 Loop in Dihydrofolate Reductase are Populated by Rapid Thermal Fluctuations
- (2009) Karunesh Arora et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Examination of Enzymatic H-Tunneling through Kinetics and Dynamics
- (2009) Jigar N. Bandaria et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Hidden alternative structures of proline isomerase essential for catalysis
- (2009) James S. Fraser et al. NATURE
- A 21st century revisionist's view at a turning point in enzymology
- (2009) Zachary D Nagel et al. Nature Chemical Biology
- Enzyme millisecond conformational dynamics do not catalyze the chemical step
- (2009) A. V. Pisliakov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rational modulation of conformational fluctuations in adenylate kinase reveals a local unfolding mechanism for allostery and functional adaptation in proteins
- (2009) T. P. Schrank et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Free-Energy Landscape of Enzyme Catalysis†
- (2008) Stephen J. Benkovic et al. BIOCHEMISTRY
- Incorporation of Hydrostatic Pressure into Models of Hydrogen Tunneling Highlights a Role for Pressure-Modulated Promoting Vibrations†
- (2008) Sam Hay et al. BIOCHEMISTRY
- Conformational Relaxation following Hydride Transfer Plays a Limiting Role in Dihydrofolate Reductase Catalysis†
- (2008) David D. Boehr et al. BIOCHEMISTRY
- Nuclear Quantum Tunneling in the Light-activated Enzyme Protochlorophyllide Oxidoreductase
- (2008) Derren J. Heyes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hydrogen-Exchange Mass Spectrometry Reveals Activation-Induced Changes in the Conformational Mobility of p38α MAP Kinase
- (2008) Kevin M. Sours et al. JOURNAL OF MOLECULAR BIOLOGY
- Proton-Coupled Electron Transfer in Solution, Proteins, and Electrochemistry†
- (2008) Sharon Hammes-Schiffer et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Evidence for Protein Radical-Mediated Nuclear Tunneling in Fatty Acid α-Oxygenase
- (2008) Ankur Gupta et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Experimental Evidence for Enzyme-Enhanced Coupled Motion/Quantum Mechanical Hydrogen Tunneling by Ketosteroid Isomerase
- (2008) Thomas C. Wilde et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Enzyme structure and dynamics affect hydrogen tunneling: The impact of a remote side chain (I553) in soybean lipoxygenase-1
- (2008) M. P. Meyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- On the relationship between folding and chemical landscapes in enzyme catalysis
- (2008) M. Roca et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Atomic detail of chemical transformation at the transition state of an enzymatic reaction
- (2008) S. Saen-oon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- De Novo Computational Design of Retro-Aldol Enzymes
- (2008) L. Jiang et al. SCIENCE
- Enzymatic reaction sequences as coupled multiple traces on a multidimensional landscape
- (2008) Liskin Swint-Kruse et al. TRENDS IN BIOCHEMICAL SCIENCES
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now