Bladder sensory physiology: neuroactive compounds and receptors, sensory transducers, and target-derived growth factors as targets to improve function

Extracellular UDP enhances P2X-mediated bladder smooth muscle contractility via P2Y6 activation of the phospholipase C/inositol trisphosphate pathway

(2013) Weiqun Yu et al.   FASEB JOURNAL

Increased TRPV4 Expression in Urinary Bladder and Lumbosacral Dorsal Root Ganglia in Mice with Chronic Overexpression of NGF in Urothelium

(2013) Beatrice M. Girard et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Lamina propria: The functional center of the bladder?

(2013) Karl-Erik Andersson et al.   NEUROUROLOGY AND URODYNAMICS

Urothelial Signaling

(2013) Lori Birder et al.   PHYSIOLOGICAL REVIEWS

From urothelial signalling to experiencing a sensation related to the urinary bladder

(2012) L. Birder et al.   Acta Physiologica

Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR Review 1

(2012) Anthony J Harmar et al.   BRITISH JOURNAL OF PHARMACOLOGY

Adrenoceptor Function and Expression in Bladder Urothelium and Lamina Propria

(2012) Christian Moro et al.   UROLOGY

Effects of TRPV4 cation channel activation on the primary bladder afferent activities of the rat

(2011) Naoki Aizawa et al.   NEUROUROLOGY AND URODYNAMICS

The role of the transient receptor potential (TRP) superfamily of cation-selective channels in the management of the overactive bladder

(2010) Karl-Erik Andersson et al.   BJU INTERNATIONAL

Extracellular ATP and P2Y Receptor Activation Induce a Proinflammatory Host Response in the Human Urinary Tract

(2010) S. Save et al.   INFECTION AND IMMUNITY

The P2Y2 Receptor Sensitizes Mouse Bladder Sensory Neurons and Facilitates Purinergic Currents

(2010) X. Chen et al.   JOURNAL OF NEUROSCIENCE

Differential purinergic signaling in bladder sensory neurons of naïve and bladder-inflamed mice

(2010) Xiaowei Chen et al.   PAIN

Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis

(2010) W. Everaerts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overexpression of NGF in mouse urothelium leads to neuronal hyperinnervation, pelvic sensitivity, and changes in urinary bladder function

(2009) Birthe Schnegelsberg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

The TRPV4 Cation Channel Mediates Stretch-evoked Ca2+Influx and ATP Release in Primary Urothelial Cell Cultures

(2009) Tsutomu Mochizuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bladder Dysfunction and Altered Somatic Sensitivity in PACAP−/− Mice

(2009) Victor May et al.   JOURNAL OF UROLOGY

Pharmacology of Vanilloid Transient Receptor Potential Cation Channels

(2009) J. Vriens et al.   MOLECULAR PHARMACOLOGY

Blockade of NGF and trk receptors inhibits increased peripheral mechanical sensitivity accompanying cystitis in rats

(2008) Simone D. Guerios et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Urinary Nerve Growth Factor Levels are Elevated in Patients with Detrusor Overactivity and Decreased in Responders to Detrusor Botulinum Toxin-A Injection

(2008) Hsin-Tzu Liu et al.   EUROPEAN UROLOGY

Differential Localizations of the Transient Receptor Potential Channels TRPV4 and TRPV1 in the Mouse Urinary Bladder

(2008) Takahiro Yamada et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

PACAP-Mediated ATP Release from Rat Urothelium and Regulation of PACAP/VIP and Receptor mRNA in Micturition Pathways after Cyclophosphamide (CYP)-Induced Cystitis

(2008) Beatrice M. Girard et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

N-((1S)-1- -3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a Novel and Potent Transient Receptor Potential Vanilloid 4 Channel Agonist Induces Urinary Bladder Contraction and Hyperactivity: Part I

(2008) K. S. Thorneloe et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Urinary Nerve Growth Factor Level Could be a Potential Biomarker for Diagnosis of Overactive Bladder

(2008) Hsin-Tzu Liu et al.   JOURNAL OF UROLOGY

The neural control of micturition

(2008) Clare J. Fowler et al.   NATURE REVIEWS NEUROSCIENCE

Lack of TRPV1 inhibits cystitis-induced increased mechanical sensitivity in mice

(2008) Zun-Yi Wang et al.   PAIN

Urinary Nerve Growth Factor Levels Are Increased in Patients with Bladder Outlet Obstruction with Overactive Bladder Symptoms and Reduced After Successful Medical Treatment

(2008) Hsin-Tzu Liu et al.   UROLOGY

Cyclophosphamide-Induced Bladder Inflammation Sensitizes and Enhances P2X Receptor Function in Rat Bladder Sensory Neurons

(2007) Khoa Dang et al.   JOURNAL OF NEUROPHYSIOLOGY

On the origin of bladder sensing: Tr(i)ps in urology

(2007) Wouter Everaerts et al.   NEUROUROLOGY AND URODYNAMICS