Novel serological neo-epitope markers of extracellular matrix proteins for the detection of portal hypertension

Extracellular Matrix Remodeling: The Common Denominator in Connective Tissue DiseasesPossibilities for Evaluation and Current Understanding of the Matrix as More Than a Passive Architecture, but a Key Player in Tissue Failure

(2012) Morten A. Karsdal et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

MMP mediated type V collagen degradation (C5M) is elevated in ankylosing spondylitis

(2012) S.S. Veidal et al.   CLINICAL BIOCHEMISTRY

Elastography, Spleen Size, and Platelet Count Identify Portal Hypertension in Patients With Compensated Cirrhosis

(2012) Annalisa Berzigotti et al.   GASTROENTEROLOGY

Von Willebrand factor as new noninvasive predictor of portal hypertension, decompensation and mortality in patients with liver cirrhosis

(2012) Monika Ferlitsch et al.   HEPATOLOGY

Enzyme-linked immunosorbent serum assay specific for the 7S domain of Collagen Type IV (P4NP 7S): A marker related to the extracellular matrix remodeling during liver fibrogenesis

(2012) Diana J. Leeming et al.   HEPATOLOGY RESEARCH

Measurement of MMP-9 and -12 degraded elastin (ELM) provides unique information on lung tissue degradation

(2012) Helene Skjøt-Arkil et al.   BMC Pulmonary Medicine

Immunological detection of the type V collagen propeptide fragment, PVCP-1230, in connective tissue remodeling associated with liver fibrosis

(2011) Efstathios Vassiliadis et al.   BIOMARKERS

A novel marker for assessment of liver matrix remodeling: An enzyme-linked immunosorbent assay (ELISA) detecting a MMP generated type I collagen neo-epitope (C1M)

(2011) DJ. Leeming et al.   BIOMARKERS

Non-Invasive markers for hepatic fibrosis

(2011) Ancha Baranova et al.   BMC GASTROENTEROLOGY

Determinants of the hyperdynamic circulation and central hypovolaemia in cirrhosis

(2011) S. Moller et al.   GUT

Von Willebrand factor levels predict clinical outcome in patients with cirrhosis and portal hypertension

(2011) V. La Mura et al.   GUT

Non invasive evaluation of portal hypertension using transient elastography

(2011) Laurent Castera et al.   JOURNAL OF HEPATOLOGY

MMP Mediated Degradation of Type VI Collagen Is Highly Associated with Liver Fibrosis – Identification and Validation of a Novel Biochemical Marker Assay

(2011) Sanne Skovgård Veidal et al.   PLoS One

A novel assay for extracellular matrix remodeling associated with liver fibrosis: An enzyme-linked immunosorbent assay (ELISA) for a MMP-9 proteolytically revealed neo-epitope of type III collagen

(2010) N. Barascuk et al.   CLINICAL BIOCHEMISTRY

Novel combinations of Post-Translational Modification (PTM) neo-epitopes provide tissue-specific biochemical markers—are they the cause or the consequence of the disease?

(2010) Morten Asser Karsdal et al.   CLINICAL BIOCHEMISTRY

Clinical Pharmacology of Portal Hypertension

(2010) Cecilia Miñano et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Noninvasive assessment of portal hypertension in patients with cirrhosis

(2010) Dominique Thabut et al.   HEPATOLOGY

Management of Varices and Variceal Hemorrhage in Cirrhosis

(2010) Guadalupe Garcia-Tsao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interleukin-1 participates in the progression from liver injury to fibrosis

(2009) Roben G. Gieling et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Biochemical markers and the FDA Critical Path: How biomarkers may contribute to the understanding of pathophysiology and provide unique and necessary tools for drug development

(2009) M.A. Karsdal et al.   BIOMARKERS

Characterization of metalloprotease cleavage products of human articular cartilage

(2008) Eugene Y. Zhen et al.   ARTHRITIS AND RHEUMATISM

Non invasive diagnosis of portal hypertension in cirrhotic patients

(2008) F. Vizzutti et al.   GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE

Expression of Matrix Metalloproteinases 2 and 9 in Donor Liver, Cirrhotic Liver, and Acute Rejection After Human Liver Transplantation

(2008) H. Kirimlioglu et al.   TRANSPLANTATION PROCEEDINGS