Biochemical markers and the FDA Critical Path: How biomarkers may contribute to the understanding of pathophysiology and provide unique and necessary tools for drug development

Markers of bone resorption predict hip fracture in elderly women: The EPIDOS prospective study

(2010) P. Garnero et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Long-term fracture prediction by bone mineral assessed at different skeletal sites

(2010) L. Joseph Melton et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Immunoaffinity liquid chromatography–tandem mass spectrometry detection of nitrotyrosine in biological fluids: Development of a clinically translatable biomarker

(2008) Melissa R. Radabaugh et al.   ANALYTICAL BIOCHEMISTRY

Use of Thiazolidinediones and Fracture Risk

(2008) Christian Meier et al.   ARCHIVES OF INTERNAL MEDICINE

Osteoclasts secrete non-bone derived signals that induce bone formation

(2008) Morten A. Karsdal et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Discovery and development of the N-terminal procollagen type II (NPII) biomarker: a tool for measuring collagen type II synthesis

(2008) O.V. Nemirovskiy et al.   OSTEOARTHRITIS AND CARTILAGE

Should subchondral bone turnover be targeted when treating osteoarthritis?

(2008) M.A. Karsdal et al.   OSTEOARTHRITIS AND CARTILAGE

The effects of oral calcitonin on bone collagen maturation: implications for bone turnover and quality

(2008) M. A. Karsdal et al.   OSTEOPOROSIS INTERNATIONAL

The disease modifying osteoarthritis drug (DMOAD): Is it in the horizon?☆

(2008) P QVIST et al.   PHARMACOLOGICAL RESEARCH

Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity

(2008) Morten A Karsdal et al.   ARTHRITIS RESEARCH & THERAPY

Reappraising metalloproteinases in rheumatoid arthritis and osteoarthritis: destruction or repair?

(2008) Gillian Murphy et al.   Nature clinical practice. Rheumatology

Relationships between biochemical markers of bone and cartilage degradation with radiological progression in patients with knee osteoarthritis receiving risedronate: the Knee Osteoarthritis Structural Arthritis randomized clinical trial

(2007) P. Garnero et al.   OSTEOARTHRITIS AND CARTILAGE