N-Imide Ylide-Based Reactions: CH Functionalization, Nucleophilic Addition and Cycloaddition

Novel Multicomponent Reactions via Trapping of Protic Onium Ylides with Electrophiles

(2013) Xin Guo et al.   ACCOUNTS OF CHEMICAL RESEARCH

Silver Triflate-Palladium Chloride Cooperative Catalysis in a Tandem Reaction for the Synthesis ofH-Pyrazolo[5,1-a]isoquinolines

(2013) Qing Xiao et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective Copper-Catalyzed [3+3] Cycloaddition of Azomethine Ylides with Azomethine Imines

(2013) Hongchao Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective Dearomatizing Formal [3+3] Cycloaddition Reactions ofN-Acyliminopyridinium Ylides with Electrophilic Enol Carbene Intermediates

(2013) Xinfang Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

[4+3] Cycloaddition of in situ generated azoalkenes with C,N-cyclic azomethine imines: efficient synthesis of tetrazepine derivatives

(2013) Xiao-Qiang Hu et al.   CHEMICAL COMMUNICATIONS

Click Chemistry for Drug Development and Diverse Chemical–Biology Applications

(2013) Prakasam Thirumurugan et al.   CHEMICAL REVIEWS

Nickel(II)-Catalyzed Enantioselective 1,3-Dipolar Cycloaddition of Azomethine Imines with Alkylidene Malonates

(2013) Jiangting Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of Azomethine Imines Using an Intramolecular Alkyne Hydrohydrazination Approach

(2013) Ashley D. Hunt et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective 1,3-Dipolar Cycloaddition of C,N-Cyclic Azomethine Imines to Unsaturated Nitriles Catalyzed by NiII–Pigiphos

(2013) Sandra Milosevic et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-Catalyzed Direct Ortho-Alkylation of N-Iminopyridinium Ylides with N-Tosylhydrazones

(2013) Qing Xiao et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Asymmetric Three-Component 1,3-Dipolar Cycloaddition of Aldehydes, Hydrazides, and Alkynes

(2013) Takuya Hashimoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A three-component reaction of C,N-cyclic N′-acyl azomethine imines, isocyanides, and azide compounds: effective synthesis of 1,5-disubstituted tetrazoles with tetrahydroisoquinoline skeletons

(2013) Takahiro Soeta et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Silver(I)-Catalyzed Addition-Cyclization of Alkyne-Functionalized Azomethines

(2013) Yuchen Liu et al.   ORGANIC LETTERS

Highly Diastereoselective DABCO-Catalyzed [3 + 3]-Cycloaddition of 1,4-Dithiane-2,5-diol with Azomethine Imines

(2013) Xin Fang et al.   ORGANIC LETTERS

Synthesis and Reactivity of Unsymmetrical Azomethine Imines Formed Using Alkene Aminocarbonylation

(2013) Wei Gan et al.   ORGANIC LETTERS

Base-Catalyzed Diastereoselective [3 + 3] Annulation of 3-Isothiocyanatooxindoles and Azomethine Imines

(2013) Gongming Zhu et al.   ORGANIC LETTERS

Bicyclic Pyrazolidinone Derivatives from Diastereoselective Catalytic [3 + 3]-Cycloaddition Reactions of Enoldiazoacetates with Azomethine Imines

(2013) Yu Qian et al.   ORGANIC LETTERS

Palladium-catalyzed oxidation of amine in air: an efficient approach to H-pyrazolo[5,1-a]-isoquinolines

(2013) Jie Sheng et al.   TETRAHEDRON

Development of Cascade Reactions for the Concise Construction of Diverse Heterocyclic Architectures

(2012) Liang-Qiu Lu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Direct Functionalization Processes: A Journey from Palladium to Copper to Iron to Nickel to Metal-Free Coupling Reactions

(2012) James J. Mousseau et al.   ACCOUNTS OF CHEMICAL RESEARCH

Phosphine-Catalyzed [3+2] and [4+3] Annulation Reactions of C,N-Cyclic Azomethine Imines with Allenoates

(2012) Chengfeng Jing et al.   ADVANCED SYNTHESIS & CATALYSIS

Rhodium(III)-Catalyzed Oxidative CH Functionalization of Azomethine Ylides

(2012) Wencui Zhen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Catalytic Asymmetric Ugi-type Reaction With Acyclic Azomethine Imines

(2012) Takuya Hashimoto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective [3+3] Cycloaddition of Aromatic Azomethine Imines with Cyclopropanes Directed by π-π Stacking Interactions

(2012) You-Yun Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Silver triflate–copper(ii) acetate cooperative catalysis in a cascade reaction for concise synthesis of 2-carbonyl H-pyrazolo[5,1-a]isoquinolines

(2012) Zhiyuan Chen et al.   CHEMICAL COMMUNICATIONS

An unexpected silver triflate-catalyzed tandem reaction of N′-(2-alkynylbenzylidene)hydrazide with ketene

(2012) Gang Liu et al.   CHEMICAL COMMUNICATIONS

Copper-catalyzed direct oxidative annulation of N-iminopyridinium ylides with terminal alkynes using O2as oxidant

(2012) Shengtao Ding et al.   CHEMICAL COMMUNICATIONS

Highly Efficient Construction of Trifluoromethylated Heterocycles; [3+2] Annulation of N,N′-Cyclic or C,N-Cyclic Azomethine Imines with Trifluoromethyl-Containing Electron-Deficient Olefins

(2012) De Wang et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

N-2-Iodobenzylcinchoninium bromide is effective for catalytic enantioselective trifluoromethylation of azomethine imines in Solkane® 365mfc

(2012) Satoshi Okusu et al.   JOURNAL OF FLUORINE CHEMISTRY

Metal Cocatalyzed Tandem Alkynylative Cyclization Reaction of in Situ Formed N-Iminoisoquinolinium Ylides with Bromoalkynes via C–H Bond Activation

(2012) Ping Huang et al.   JOURNAL OF ORGANIC CHEMISTRY

A Tunable Route for the Synthesis of Azomethine Imines and β-Aminocarbonyl Compounds from Alkenes

(2012) Christian Clavette et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Group 11 Metal Amide-Catalyzed Asymmetric Cycloaddition Reactions of Azomethine Imines with Terminal Alkynes

(2012) Takaki Imaizumi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral Bis(Imidazolidine)Pyridine-Cu Complex-Catalyzed Enantioselective [3+2]-Cycloaddition of Azomethine Imines with Propiolates

(2012) Takayoshi Arai et al.   MOLECULES

Silver triflate-catalyzed tandem reaction of N′-(2-alkynylbenzylidene)hydrazide with pyridyne

(2012) Lingyong Jiang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of pyrazolo[5,1-a]isoquinolines via silver(i)–rhodium(i) cooperative catalysis in the reaction of N′-(2-alkynylbenzylidene)hydrazide with cycloprop-2-ene-1,1-dicarboxylate

(2012) Liangqing Yao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Regioselective Synthesis of Pyrazole Triflones Based on Triflyl Alkyne Cycloadditions

(2012) Hiroyuki Kawai et al.   ORGANIC LETTERS

[5 + 1] Cycloaddition of C,N-Cyclic N′-Acyl Azomethine Imines with Isocyanides

(2012) Takahiro Soeta et al.   ORGANIC LETTERS

Generation of diverse 1-(isoquinolin-1-yl)guanidines via a sequential multi-component/cross-coupling reaction

(2012) Chao Ye et al.   TETRAHEDRON

Thermal [3+2] cycloaddition reaction of azomethine imines with allenoates for dinitrogen-fused heterocycles

(2012) Risong Na et al.   TETRAHEDRON

A silver(I)–rhodium(I) cooperative catalysis in the reaction of N′-(2-alkynylbenzylidene)hydrazide with 2-vinyloxirane

(2012) Hongliang Liu et al.   TETRAHEDRON

Reaction of N′-(2-alkynylbenzylidene)hydrazide with tertiary amine: a concise synthesis of H-pyrazolo[5,1-a]isoquinolines

(2012) Chao Ye et al.   RSC Advances

2-Alkynylbenzaldehyde: A Versatile Building Block for the Generation of Cyclic Compounds

(2012) Huanhuan Wang et al.   Asian Journal of Organic Chemistry

Zirconocene and Si-Tethered Diynes: A Happy Match Directed toward Organometallic Chemistry and Organic Synthesis

(2011) Wen-Xiong Zhang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Click Dendrimers and Triazole-Related Aspects: Catalysts, Mechanism, Synthesis, and Functions. A Bridge between Dendritic Architectures and Nanomaterials

(2011) Didier Astruc et al.   ACCOUNTS OF CHEMICAL RESEARCH

Catalytic Asymmetric Alkynylation of C1-Substituted C,N-Cyclic Azomethine Imines by CuI/Chiral Brønsted Acid Co-Catalyst

(2011) Takuya Hashimoto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Inverse-Electron-Demand 1,3-Dipolar Cycloaddition of C,N-Cyclic Azomethine Imines: An Umpolung Strategy

(2011) Takuya Hashimoto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Organocatalytic Cyclization and Cycloaddition Reactions

(2011) Albert Moyano et al.   CHEMICAL REVIEWS

An Efficient, Ligand-Free, Heterogeneous Supported Copper Hydroxide Catalyst for the Synthesis of N,N-Bicyclic Pyrazolidinone Derivatives

(2011) Kazuaki Yoshimura et al.   CHEMISTRY-A EUROPEAN JOURNAL

Nucleophilic Trifluoromethylation of C=N Bonds

(2011) Alexander D. Dilman et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of 2- and 2,3-Substituted Pyrazolo[1,5-a]pyridines: Scope and Mechanistic Considerations of a Domino Direct Alkynylation and Cyclization ofN-Iminopyridinium Ylides Using Alkenyl Bromides, Alkenyl Iodides, and Alkynes

(2011) James J. Mousseau et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Pyrido[1,2-b]indazoles via Aryne [3 + 2] Cycloaddition withN-Tosylpyridinium Imides

(2011) Jingjing Zhao et al.   JOURNAL OF ORGANIC CHEMISTRY

Phosphine-Catalyzed Annulations of Azomethine Imines: Allene-Dependent [3 + 2], [3 + 3], [4 + 3], and [3 + 2 + 3] Pathways

(2011) Risong Na et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Generation and exploitation of acyclic azomethine imines in chiral Brønsted acid catalysis

(2011) Takuya Hashimoto et al.   Nature Chemistry

An efficient approach to pyrazolo[5,1-a]isoquinolin-2-amines via a silver(i)-catalyzed three-component reaction of 2-alkynylbenzaldehyde, sulfonohydrazide, and nitrile

(2011) Xingxin Yu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cascade cyclization, dipolar cycloaddition of azomethine imines for the synthesis of pyrazolidines

(2011) Hélène D. S. Guerrand et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Aryne [3 + 2] cycloaddition with N-sulfonylpyridinium imides and in situ generated N-sulfonylisoquinolinium imides: a potential route to pyrido[1,2-b]indazoles and indazolo[3,2-a]isoquinolines

(2011) Jingjing Zhao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly Regioselective [3 + 2] Annulation of Azomethine Imines with 1-Alkynyl Fischer Carbene Complexes to FunctionalizedN,N-Bicyclic Pyrazolidin-3-ones

(2011) Ning Luo et al.   ORGANIC LETTERS

Synthesis ofH-Pyrazolo[5,1-a]isoquinolines via Copper(II)-Catalyzed Oxidation of an Aliphatic C−H Bond of Tertiary Amine in Air

(2011) Shaoyu Li et al.   ORGANIC LETTERS

Three-Component Reaction ofN′-(2-Alkynylbenzylidene)hydrazide, Alkyne, with Sulfonyl Azide via a Multicatalytic Process: A Novel and Concise Approach to 2-Amino-H-pyrazolo[5,1-a]isoquinolines

(2011) Shaoyu Li et al.   ORGANIC LETTERS

Stereoselective synthesis of polyoxygenated linear diaza-triquinanes via intramolecular 1,3-dipolar cycloaddition of sugar-derived hex-5-enals

(2011) Yunfeng Li et al.   TETRAHEDRON

An expeditious approach to 1-(isoquinolin-1-yl)guanidines via a three-component reaction of 2-alkynylbenzaldehyde, sulfonohydrazide, with carbodiimide

(2011) Huanhuan Wang et al.   TETRAHEDRON

Facile Assembly of H-Pyrazolo[5,1-a]isoquinolines via Silver Triflate-Catalyzed One-Pot Tandem Reaction of 2-Alkynyl- benzaldehyde, Sulfonohydrazide, and Ketone or Aldehyde

(2010) Xingxin Yu et al.   ADVANCED SYNTHESIS & CATALYSIS

Combination Catalysis in Enantioselective Trifluoromethylation

(2010) Yan Zheng et al.   ADVANCED SYNTHESIS & CATALYSIS

Silver triflate and N-heterocyclic carbene co-catalyzed reaction of N′-(2-alkynylbenzylidene)hydrazide, methanol with α,β-unsaturated aldehyde

(2010) Zhiyuan Chen et al.   CHEMICAL COMMUNICATIONS

Silver triflate-catalyzed three-component reaction of 2-alkynylbenzaldehyde, sulfonohydrazide, and α,β-unsaturated carbonyl compound

(2010) Shengqing Ye et al.   CHEMICAL COMMUNICATIONS

Asymmetric 1,3-Dipolar Cycloaddition of Azomethine Imines to Homoallylic Alcohols

(2010) Katsuyoshi Tanaka et al.   CHEMISTRY LETTERS

Tandem Reactions ofN′-(2-Alkynylbenzylidene)hydrazides with Silyl Enolates: A Facile Route toH-Pyrazolo[5,1-a]isoquinolines

(2010) Xingxin Yu et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Cu(I)-Catalyzed Regioselective Diamination of Conjugated Dienes via Dual Mechanistic Pathways

(2010) Baoguo Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Enantioselective 1,3-Dipolar Cycloaddition of C,N-Cyclic Azomethine Imines with α,β-Unsaturated Aldehydes

(2010) Takuya Hashimoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Asymmetric Arylation of Azomethine Imines

(2010) Ryo Shintani et al.   ORGANIC LETTERS

Efficient Generation of Biologically ActiveH-Pyrazolo[5,1-a]isoquinolines via Multicomponent Reaction

(2010) Zhiyuan Chen et al.   ORGANIC LETTERS

Synthesis of 2-Substituted Pyrazolo[1,5-a]pyridines through Cascade Direct Alkenylation/Cyclization Reactions

(2010) James J. Mousseau et al.   ORGANIC LETTERS

Three-component reaction of N′-(2-alkynylbenzylidene)hydrazide, α,β-unsaturated carbonyl compound, with bromine

(2010) Hui Ren et al.   TETRAHEDRON

An efficient route to diverse H-pyrazolo[5,1-a]isoquinolines via sequential multi-component/cross-coupling reactions

(2010) Xingxin Yu et al.   TETRAHEDRON

Silver Triflate-Catalyzed or Electrophile-Mediated Tandem Reaction ofN′-(2-Alkynylbenzylidene)hydrazides with Dimethyl Acetylenedicarboxylate

(2009) Zhiyuan Chen et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic Enantioselective Trifluoromethylation of Azomethine Imines with Trimethyl(trifluoromethyl)silane

(2009) Hiroyuki Kawai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Direct Alkenylation ofN-Iminopyridinium Ylides

(2009) James J. Mousseau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper(I) Iodide-Catalyzed Cycloadditions of (1Z,4R*,5R*)-4-Benzamido-5-phenylpyrazolidin-3-on-1-azomethine Imines to Ethyl Propiolate

(2009) Lidija Pezdirc et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

AgOTf-catalyzed tandem reaction of N′-(2-alkynylbenzylidene)hydrazide with alkyne

(2009) Zhiyuan Chen et al.   CHEMICAL COMMUNICATIONS

Applications of Orthogonal “Click” Chemistries in the Synthesis of Functional Soft Materials

(2009) Rhiannon K. Iha et al.   CHEMICAL REVIEWS

Cu(I)-Catalyzed Huisgen Azide−Alkyne 1,3-Dipolar Cycloaddition Reaction in Nucleoside, Nucleotide, and Oligonucleotide Chemistry

(2009) Franck Amblard et al.   CHEMICAL REVIEWS

Copper(I) Zeolites as Heterogeneous and Ligand-Free Catalysts: [3+2] Cycloaddition of Azomethine Imines

(2009) Murielle Keller et al.   CHEMISTRY-A EUROPEAN JOURNAL

Iridium Catalyzed Enantioselective Hydrogenation of N-Iminopyridinium Ylides: Mechanistic Insights

(2009) André B. Charette et al.   HETEROCYCLES

Gold-Catalyzed [3+3]-Annulation of Azomethine Imines with Propargyl Esters

(2009) Nathan D. Shapiro et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multicatalytic tandem reaction of N′-(2-alkynylbenzylidene)hydrazide with indole

(2009) Xingxin Yu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of functionalized H-pyrazolo[5,1-a]isoquinolines via sequential reactions of N′-(2-alkynylbenzylidene)hydrazides

(2009) Zhiyuan Chen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Lewis acid-catalyzed reactions of N′-(2-alkynylbenzylidene)hydrazides with diethyl phosphite

(2009) Xingxin Yu et al.   TETRAHEDRON LETTERS

1,3-Dipolar cycloaddition of arynes with azomethine imines: synthesis of 1,2-dihydropyrazolo[1,2-a]indazol-3(9H)-ones

(2009) Feng Shi et al.   TETRAHEDRON LETTERS

Evolution of a Fourth Generation Catalyst for the Amination and Thioetherification of Aryl Halides

(2008) John F. Hartwig   ACCOUNTS OF CHEMICAL RESEARCH

Copper/Amino Acid Catalyzed Cross-Couplings of Aryl and Vinyl Halides with Nucleophiles†

(2008) Dawei Ma et al.   ACCOUNTS OF CHEMICAL RESEARCH

Ylide-Initiated Michael Addition−Cyclization Reactions beyond Cyclopropanes

(2008) Xiu-Li Sun et al.   ACCOUNTS OF CHEMICAL RESEARCH

Biaryl Phosphane Ligands in Palladium-Catalyzed Amination

(2008) David S. Surry et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Copper-Catalyzed 1,3-Dipolar Cycloadditions

(2008) Levi M. Stanley et al.   CHEMICAL REVIEWS

Asymmetric 1,3-Dipolar Cycloaddition Reaction of Azomethine Imines to Allyl Alcohol

(2008) Tomomitsu Kato et al.   CHEMISTRY LETTERS

Copper(II)-Catalyzed Exo and Enantioselective Cycloadditions of Azomethine Imines

(2008) Mukund P. Sibi et al.   ORGANIC LETTERS

Palladium-Catalyzed Benzylic C−H Insertion of 2-SubstitutedN-Iminopyridinium Ylides

(2008) James J. Mousseau et al.   ORGANIC LETTERS

Cycloadditions of Aromatic Azomethine Imines with 1,1-Cyclopropane Diesters

(2008) Christian Perreault et al.   ORGANIC LETTERS

Highly efficient electrophilic cyclization of N′-(2-alkynylbenzylidene)hydrazides

(2008) Qiuping Ding et al.   TETRAHEDRON LETTERS

Palladium-Catalyzed Direct C−H Arylation ofN-Iminopyridinium Ylides:  Application to the Synthesis of (±)-Anabasine

(2007) Alexandre Larivée et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY