期刊
ORGANIC LETTERS
卷 15, 期 8, 页码 1890-1893出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol400542b
关键词
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资金
- University of Ottawa
- NSERC
- Canadian Foundation for Innovation
- Ontario Ministry of Research and Innovation
- AstraZeneca Canada
- GreenCentre Canada
- Omega-Chem
- NSERC (CREATE on medicinal chemistry and bio-pharmaceutical development)
- OGS
Complex cyclic azomethine imines possessing a beta-aminocarbonyl motif can be accessed readily from simple alkenes and hydrazones. This alkene aminocarbonylation approach allows formation of ketone-derived azomethine imines of unprecedented complexity. Since unsymmetrical hydrazones are used, two stereoisomers are formed: the reactivity of chiral derivatives is explored in both intra- and intermolecular systems.
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