Synthesis of pyrazolo[5,1-a]isoquinolines via silver(i)–rhodium(i) cooperative catalysis in the reaction of N′-(2-alkynylbenzylidene)hydrazide with cycloprop-2-ene-1,1-dicarboxylate

Silver triflate–copper(ii) acetate cooperative catalysis in a cascade reaction for concise synthesis of 2-carbonyl H-pyrazolo[5,1-a]isoquinolines

(2012) Zhiyuan Chen et al.   CHEMICAL COMMUNICATIONS

Metal Cocatalyzed Tandem Alkynylative Cyclization Reaction of in Situ Formed N-Iminoisoquinolinium Ylides with Bromoalkynes via C–H Bond Activation

(2012) Ping Huang et al.   JOURNAL OF ORGANIC CHEMISTRY

Silver Triflate and Palladium Acetate Co-catalyzed Reaction of N′-(2-Alkynylbenzylidene)hydrazide with N-Allyl Ynamide

(2012) Ping Huang et al.   ORGANIC LETTERS

Concise and efficient one-pot copper-catalyzed synthesis of H-pyrazolo[5,1-a]isoquinolines

(2012) Xiaobo Yang et al.   RSC Advances

Silver-Catalyzed exo-dig-Azacyclization/[3+2] Cycloaddition Cascades on 1-Tosylhydrazon-4-oxy-5-yne Substrates: Applicability to Diverse Alkenes

(2011) Deepak B. Huple et al.   ADVANCED SYNTHESIS & CATALYSIS

Domino Rhodium-Catalyzed Alkyne Arylation/Palladium-Catalyzed N Arylation: A Mechanistic Investigation

(2011) Jane Panteleev et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A design strategy for drug-like polyheterocycles with privileged substructures for discovery of specific small-molecule modulators

(2011) Sangmi Oh et al.   CHEMICAL COMMUNICATIONS

Synthesis and Photochemical Investigations of Tetrasubstituted Alkenes as Molecular Switches-The Effect of Substituents

(2011) Lutz F. Tietze et al.   CHEMISTRY-A EUROPEAN JOURNAL

Sulfonyl and Phosphoryl Azides: Going Further Beyond the Click Realm of Alkyl and Aryl Azides

(2011) Seok Hwan Kim et al.   Chemistry-An Asian Journal

Rhodium(III)-Catalyzed Oxidative Coupling of 5-Aryl-1H-pyrazoles with Alkynes and Acrylates

(2011) Xingwei Li et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Pyrido[1,2-b]indazoles via Aryne [3 + 2] Cycloaddition withN-Tosylpyridinium Imides

(2011) Jingjing Zhao et al.   JOURNAL OF ORGANIC CHEMISTRY

N-Heterocyclic Carbene (NHC)-Catalyzed Intermolecular Hydroacylation of Cyclopropenes

(2011) Xavier Bugaut et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aryne [3 + 2] cycloaddition with N-sulfonylpyridinium imides and in situ generated N-sulfonylisoquinolinium imides: a potential route to pyrido[1,2-b]indazoles and indazolo[3,2-a]isoquinolines

(2011) Jingjing Zhao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Silver Triflate-Catalyzed Cyclopropenation of Internal Alkynes with Donor-/Acceptor-Substituted Diazo Compounds

(2011) John F. Briones et al.   ORGANIC LETTERS

Organic synthesis toward small-molecule probes and drugs

(2011) S. L. Schreiber   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhancements of screening collections to address areas of unmet medical need: an industry perspective

(2010) David H Drewry et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

When Organocatalysis Meets Transition-Metal Catalysis

(2010) Cheng Zhong et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Desymmetrization of Cyclopropenes by Hydroacylation

(2010) Diem H. T. Phan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Grand Challenge Commentary: Accessing new chemical space for 'undruggable' targets

(2010) Sivaraman Dandapani et al.   Nature Chemical Biology

Synthesis of 2-Substituted Pyrazolo[1,5-a]pyridines through Cascade Direct Alkenylation/Cyclization Reactions

(2010) James J. Mousseau et al.   ORGANIC LETTERS

Tandem Cyclopropane Ring-Opening/Conia-ene Reactions of 2-Alkynyl Indoles: A [3 + 3] Annulative Route to Tetrahydrocarbazoles

(2010) Huck K. Grover et al.   ORGANIC LETTERS

Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules

(2010) Warren R.J.D. Galloway et al.   Nature Communications

Combining transition metal catalysis and organocatalysis: a broad new concept for catalysis

(2009) Zhihui Shao et al.   CHEMICAL SOCIETY REVIEWS

Molecular diversity by design

(2009) Stuart L. Schreiber   NATURE

Chemical biology—identification of small molecule modulators of cellular activity by natural product inspired synthesis

(2008) Katja Hübel et al.   CHEMICAL SOCIETY REVIEWS

Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries

(2008) Christopher Cordier et al.   NATURAL PRODUCT REPORTS