EBNA1: Oncogenic Activity, Immune Evasion and Biochemical Functions Provide Targets for Novel Therapeutic Strategies against Epstein-Barr Virus- Associated Cancers
出版年份 2018 全文链接
标题
EBNA1: Oncogenic Activity, Immune Evasion and Biochemical Functions Provide Targets for Novel Therapeutic Strategies against Epstein-Barr Virus- Associated Cancers
作者
关键词
-
出版物
Cancers
Volume 10, Issue 4, Pages 109
出版商
MDPI AG
发表日期
2018-04-11
DOI
10.3390/cancers10040109
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Epstein-Barr virus (EBV) provides survival factors to EBV+ diffuse large B-cell lymphoma (DLBCL) lines and modulates cytokine induced specific chemotaxis in EBV+ DLBCL
- (2017) Liang Wu et al. IMMUNOLOGY
- Epstein–Barr virus nuclear antigen 1 interacts with regulator of chromosome condensation 1 dynamically throughout the cell cycle
- (2017) Thibaut Deschamps et al. JOURNAL OF GENERAL VIROLOGY
- Structural and Functional Basis for an EBNA1 Hexameric Ring in Epstein-Barr Virus Episome Maintenance
- (2017) Julianna S. Deakyne et al. JOURNAL OF VIROLOGY
- Natural Variation of Epstein-Barr Virus Genes, Proteins, and Primary MicroRNA
- (2017) Samantha Correia et al. JOURNAL OF VIROLOGY
- PI3Kδ activates E2F1 synthesis in response to mRNA translation stress
- (2017) Sivakumar Vadivel Gnanasundram et al. Nature Communications
- Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA
- (2017) María José Lista et al. Nature Communications
- Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency
- (2017) Jayaraju Dheekollu et al. Oncotarget
- Humanized mouse models for Epstein Barr virus infection
- (2017) Christian Münz Current Opinion in Virology
- Recent advances in viral evasion of the MHC Class I processing pathway
- (2016) Anouk BC Schuren et al. CURRENT OPINION IN IMMUNOLOGY
- Computational analysis of EBNA1 “druggability” suggests novel insights for Epstein-Barr virus inhibitor design
- (2016) Eleonora Gianti et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- HCF1 and OCT2 Cooperate with EBNA1 To Enhance OriP-Dependent Transcription and Episome Maintenance of Latent Epstein-Barr Virus
- (2016) Jayaraju Dheekollu et al. JOURNAL OF VIROLOGY
- Modulation of the p53/MDM2 interplay by HAUSP inhibitors
- (2016) Omid Tavana et al. Journal of Molecular Cell Biology
- The long-lasting love affair between the budding yeastSaccharomyces cerevisiaeand the Epstein-Barr virus
- (2015) María José Lista et al. Biotechnology Journal
- Identification of MEF2B , EBF1 , and IL6R as Direct Gene Targets of Epstein-Barr Virus (EBV) Nuclear Antigen 1 Critical for EBV-Infected B-Lymphocyte Survival
- (2015) Italo Tempera et al. JOURNAL OF VIROLOGY
- The AT-hook DNA binding ability of the Epstein Barr virus EBNA1 protein is necessary for the maintenance of viral genomes in latently infected cells
- (2015) Adityarup Chakravorty et al. VIROLOGY
- The long-lasting love affair between the budding yeastSaccharomyces cerevisiaeand the Epstein-Barr virus
- (2015) María José Lista et al. Biotechnology Journal
- Small molecule inhibition of Epstein–Barr virus nuclear antigen-1 DNA binding activity interferes with replication and persistence of the viral genome
- (2014) Eun Kyung Lee et al. ANTIVIRAL RESEARCH
- Epstein-Barr Virus Serology as a Potential Screening Marker for Nasopharyngeal Carcinoma among High-Risk Individuals from Multiplex Families in Taiwan
- (2014) A. E. Coghill et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- A yeast-based assay identifies drugs that interfere with immune evasion of the Epstein-Barr virus
- (2014) C. Voisset et al. Disease Models & Mechanisms
- Epstein-Barr virus-encoded EBNA1 and ZEBRA: targets for therapeutic strategies against EBV-carrying cancers
- (2014) Chrysoula Daskalogianni et al. JOURNAL OF PATHOLOGY
- Epstein-Barr Virus EBNA1 Protein Regulates Viral Latency through Effects on let-7 MicroRNA and Dicer
- (2014) S. Mansouri et al. JOURNAL OF VIROLOGY
- G-quadruplexes regulate Epstein-Barr virus–encoded nuclear antigen 1 mRNA translation
- (2014) Pierre Murat et al. Nature Chemical Biology
- The V-val subtype Epstein-Barr virus nuclear antigen 1 promotes cell survival after serum withdrawal
- (2014) MEI CHAO et al. ONCOLOGY REPORTS
- EBNA1 binding and epigenetic regulation of gastrokine tumor suppressor genes in gastric carcinoma cells
- (2014) Fang Lu et al. Virology Journal
- Modelling the structure of full-length Epstein–Barr virus nuclear antigen 1
- (2014) Mushtaq Hussain et al. VIRUS GENES
- Signaling by the Phosphoinositide 3-Kinase Family in Immune Cells
- (2013) Klaus Okkenhaug Annual Review of Immunology
- Pathways of Antigen Processing
- (2013) Janice S. Blum et al. Annual Review of Immunology
- Cell Cycle-Dependent Binding Modes of the Ran Exchange Factor RCC1 to Chromatin
- (2013) Martin Bierbaum et al. BIOPHYSICAL JOURNAL
- Interaction between Basic Residues of Epstein-Barr Virus EBNA1 Protein and Cellular Chromatin Mediates Viral Plasmid Maintenance
- (2013) Teru Kanda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Nucleophosmin Contributes to the Transcriptional Activation Function of the Epstein-Barr Virus EBNA1 Protein
- (2013) N. Malik-Soni et al. JOURNAL OF VIROLOGY
- Efficient Replication of Epstein-Barr Virus-Derived Plasmids Requires Tethering by EBNA1 to Host Chromosomes
- (2013) Theresa L. Hodin et al. JOURNAL OF VIROLOGY
- The Epstein–Barr virus nuclear antigen-1 reprograms transcription by mimicry of high mobility group A proteins
- (2013) Giuseppe Coppotelli et al. NUCLEIC ACIDS RESEARCH
- Nucleolin is important for Epstein-Barr virus nuclear antigen 1-mediated episome binding, maintenance, and transcription
- (2013) Y.-L. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Small molecule and peptide-mediated inhibition of Epstein-Barr virus nuclear antigen 1 dimerization
- (2012) Sun Young Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Synergy between PI3K Signaling and MYC in Burkitt Lymphomagenesis
- (2012) Sandrine Sander et al. CANCER CELL
- An Atlas of the Epstein-Barr Virus Transcriptome and Epigenome Reveals Host-Virus Regulatory Interactions
- (2012) Aaron Arvey et al. Cell Host & Microbe
- Epstein-Barr Nuclear Antigen 1 (EBNA1)-dependent Recruitment of Origin Recognition Complex (Orc) onoriPof Epstein-Barr Virus with Purified Proteins
- (2012) Kenji Moriyama et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Live-Cell Imaging Reveals Multiple Interactions between Epstein-Barr Virus Nuclear Antigen 1 and Cellular Chromatin during Interphase and Mitosis
- (2012) N. Jourdan et al. JOURNAL OF VIROLOGY
- Functions of the Epstein-Barr Virus EBNA1 Protein in Viral Reactivation and Lytic Infection
- (2012) N. Sivachandran et al. JOURNAL OF VIROLOGY
- The genetic landscape of mutations in Burkitt lymphoma
- (2012) Cassandra Love et al. NATURE GENETICS
- Establishment of VCA and EBNA1 IgA-based combination by enzyme-linked immunosorbent assay as preferred screening method for nasopharyngeal carcinoma: a two-stage design with a preliminary performance study and a mass screening in southern China
- (2011) Yue Liu et al. INTERNATIONAL JOURNAL OF CANCER
- Contributions of the Epstein-Barr Virus EBNA1 Protein to Gastric Carcinoma
- (2011) N. Sivachandran et al. JOURNAL OF VIROLOGY
- EBV Latency Types Adopt Alternative Chromatin Conformations
- (2011) Italo Tempera et al. PLoS Pathogens
- E2F1 inhibits MDM2 expression in a p53-dependent manner
- (2010) Xu Tian et al. CELLULAR SIGNALLING
- RCC1 Uses a Conformationally Diverse Loop Region to Interact with the Nucleosome: A Model for the RCC1–Nucleosome Complex
- (2010) Joseph R. England et al. JOURNAL OF MOLECULAR BIOLOGY
- Epstein-Barr Virus Nuclear Antigen 1 Hijacks the Host Kinase CK2 To Disrupt PML Nuclear Bodies
- (2010) N. Sivachandran et al. JOURNAL OF VIROLOGY
- Epstein-Barr virus-encoded EBNA1 enhances RNA polymerase III-dependent EBER expression through induction of EBER-associated cellular transcription factors
- (2010) Thomas J Owen et al. Molecular Cancer
- Structure of RCC1 chromatin factor bound to the nucleosome core particle
- (2010) Ravindra D. Makde et al. NATURE
- Transcription Profiling of Epstein-Barr Virus Nuclear Antigen (EBNA)-1 Expressing Cells Suggests Targeting of Chromatin Remodeling Complexes
- (2010) Ramakrishna Sompallae et al. PLoS One
- Hsp90 inhibitors block outgrowth of EBV-infected malignant cells in vitro and in vivo through an EBNA1-dependent mechanism
- (2010) X. Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epstein–Barr Virus nuclear antigen 1 (EBNA1) confers resistance to apoptosis in EBV-positive B-lymphoma cells through up-regulation of survivin
- (2010) Jie Lu et al. VIROLOGY
- Genome-wide analysis of host-chromosome binding sites for Epstein-Barr Virus Nuclear Antigen 1 (EBNA1)
- (2010) Fang Lu et al. Virology Journal
- Epstein Barr Virus-Encoded EBNA1 Interference with MHC Class I Antigen Presentation Reveals a Close Correlation between mRNA Translation Initiation and Antigen Presentation
- (2010) Sebastien Apcher et al. PLoS Pathogens
- Mitotic chromosome interactions of Epstein-Barr nuclear antigen 1 (EBNA1) and human EBNA1-binding protein 2 (EBP2)
- (2009) V. K. Nayyar et al. JOURNAL OF CELL SCIENCE
- Phosphorylation sites of Epstein-Barr virus EBNA1 regulate its function
- (2009) S. J. Duellman et al. JOURNAL OF GENERAL VIROLOGY
- The Latent Origin of Replication of Epstein-Barr Virus Directs Viral Genomes to Active Regions of the Nucleus
- (2009) M. J. Deutsch et al. JOURNAL OF VIROLOGY
- Nucleosome Assembly Proteins Bind to Epstein-Barr Virus Nuclear Antigen 1 and Affect Its Functions in DNA Replication and Transcriptional Activation
- (2009) S. Wang et al. JOURNAL OF VIROLOGY
- Identifying Sites Bound by Epstein-Barr Virus Nuclear Antigen 1 (EBNA1) in the Human Genome: Defining a Position-Weighted Matrix To Predict Sites Bound by EBNA1 in Viral Genomes
- (2009) L. R. Dresang et al. JOURNAL OF VIROLOGY
- Role for G-Quadruplex RNA Binding by Epstein-Barr Virus Nuclear Antigen 1 in DNA Replication and Metaphase Chromosome Attachment
- (2009) J. Norseen et al. JOURNAL OF VIROLOGY
- EBNA1 regulates cellular gene expression by binding cellular promoters
- (2009) Allon Canaan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Zinc Coordination Is Required for and Regulates Transcription Activation by Epstein-Barr Nuclear Antigen 1
- (2009) Siddhesh Aras et al. PLoS Pathogens
- RNA-dependent recruitment of the origin recognition complex
- (2008) Julie Norseen et al. EMBO JOURNAL
- Gly-Ala Repeats Induce Position- and Substrate-specific Regulation of 26 S Proteasome-dependent Partial Processing
- (2008) Chrysoula Daskalogianni et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Epstein-Barr virus nuclear antigen-1 renders lymphocytes responsive to IL-2 but not IL-15 for survival
- (2008) P. Tsimbouri et al. JOURNAL OF GENERAL VIROLOGY
- Epstein-Barr virus-encoded EBNA1 modulates the AP-1 transcription factor pathway in nasopharyngeal carcinoma cells and enhances angiogenesis in vitro
- (2008) J. D. O'Neil et al. JOURNAL OF GENERAL VIROLOGY
- mRNA Translation Regulation by the Gly-Ala Repeat of Epstein-Barr Virus Nuclear Antigen 1
- (2008) S. Apcher et al. JOURNAL OF VIROLOGY
- The EBNA1 Protein of Epstein-Barr Virus Functionally Interacts with Brd4
- (2008) A. Lin et al. JOURNAL OF VIROLOGY
- Regulation of protein translation through mRNA structure influences MHC class I loading and T cell recognition
- (2008) J. Tellam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interaction between HMGA1a and the origin recognition complex creates site-specific replication origins
- (2008) A. W. Thomae et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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