De novo biosynthesis of sterols and fatty acids in the Trypanosoma brucei procyclic form: Carbon source preferences and metabolic flux redistributions

Characterization and role of the 3-methylglutaconyl coenzyme A hidratase in Trypanosoma brucei

(2017) Mariana Leão de Lima Stein et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Proline Metabolism is Essential for Trypanosoma brucei brucei Survival in the Tsetse Vector

(2017) Brian S. Mantilla et al.   PLoS Pathogens

Acetyl-CoA and the regulation of metabolism: mechanisms and consequences

(2015) Lei Shi et al.   CURRENT OPINION IN CELL BIOLOGY

Combining reverse genetics and nuclear magnetic resonance-based metabolomics unravels trypanosome-specific metabolic pathways

(2015) Frédéric Bringaud et al.   MOLECULAR MICROBIOLOGY

Probing the Metabolic Network in Bloodstream-Form Trypanosoma brucei Using Untargeted Metabolomics with Stable Isotope Labelled Glucose

(2015) Darren J. Creek et al.   PLoS Pathogens

Acquisition and biosynthesis of saturated and unsaturated fatty acids by trypanosomatids

(2014) Antonio D. Uttaro   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The growing landscape of lysine acetylation links metabolism and cell signalling

(2014) Chunaram Choudhary et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Triacylglycerol Storage in Lipid Droplets in Procyclic Trypanosoma brucei

(2014) Stefan Allmann et al.   PLoS One

Cyclic AMP Effectors in African Trypanosomes Revealed by Genome-Scale RNA Interference Library Screening for Resistance to the Phosphodiesterase Inhibitor CpdA

(2013) Matthew K. Gould et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Crystal structures of SCP2-thiolases of Trypanosomatidae, human pathogens causing widespread tropical diseases: the importance for catalysis of the cysteine of the unique HDCF loop

(2013) Rajesh K. Harijan et al.   BIOCHEMICAL JOURNAL

Cytosolic NADPH Homeostasis in Glucose-starved ProcyclicTrypanosoma bruceiRelies on Malic Enzyme and the Pentose Phosphate Pathway Fed by Gluconeogenic Flux

(2013) Stefan Allmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid synthesis in protozoan parasites: A comparison between kinetoplastids and apicomplexans

(2013) Srinivasan Ramakrishnan et al.   PROGRESS IN LIPID RESEARCH

Proteome remodelling during development from blood to insect-form Trypanosoma brucei quantified by SILAC and mass spectrometry

(2012) Kapila Gunasekera et al.   BMC GENOMICS

Endogenous sterol biosynthesis is important for mitochondrial function and cell morphology in procyclic forms of Trypanosoma brucei

(2012) Guiomar Pérez-Moreno et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

ATP Synthesis-coupled and -uncoupled Acetate Production from Acetyl-CoA by Mitochondrial Acetate:Succinate CoA-transferase and Acetyl-CoA Thioesterase inTrypanosoma

(2012) Yoann Millerioux et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysine Acetylation: Elucidating the Components of an Emerging Global Signaling Pathway in Trypanosomes

(2012) Victoria Lucia Alonso et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Mitochondrial Outer Membrane Proteome ofTrypanosoma bruceiReveals Novel Factors Required to Maintain Mitochondrial Morphology

(2012) Moritz Niemann et al.   MOLECULAR & CELLULAR PROTEOMICS

Estimating and Mapping the Population at Risk of Sleeping Sickness

(2012) Pere P. Simarro et al.   PLoS Neglected Tropical Diseases

Novel sterol metabolic network ofTrypanosoma bruceiprocyclic and bloodstream forms

(2011) Craigen R. Nes et al.   BIOCHEMICAL JOURNAL

Multiple roles of proline transport and metabolism in trypanosomatids

(2011) Frederic Bringaud   Frontiers in Bioscience-Landmark

The characterization and evolutionary relationships of a trypanosomal thiolase

(2011) Muriel Mazet et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Metabolomic analysis of trypanosomatid protozoa

(2011) Darren J. Creek et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Requirement for acetyl-CoA carboxylase in Trypanosoma brucei is dependent upon the growth environment

(2011) Patrick A. Vigueira et al.   MOLECULAR MICROBIOLOGY

Molecular bases of cytoskeleton plasticity during the Trypanosoma brucei parasite cycle

(2010) Brice Rotureau et al.   CELLULAR MICROBIOLOGY

Ablation of Succinate Production from Glucose Metabolism in the Procyclic Trypanosomes Induces Metabolic Switches to the Glycerol 3-Phosphate/Dihydroxyacetone Phosphate Shuttle and to Proline Metabolism

(2010) Charles Ebikeme et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid metabolism in Trypanosoma brucei

(2010) Terry K. Smith et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The Trypanosoma brucei MitoCarta and its regulation and splicing pattern during development

(2010) Xiaobai Zhang et al.   NUCLEIC ACIDS RESEARCH

Acetylation of Metabolic Enzymes Coordinates Carbon Source Utilization and Metabolic Flux

(2010) Q. Wang et al.   SCIENCE

Acetate produced in the mitochondrion is the essential precursor for lipid biosynthesis in procyclic trypanosomes

(2009) L. Riviere et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The 3-hydroxyacyl-ACP dehydratase of mitochondrial fatty acid synthesis inTrypanosoma brucei

(2008) Kaija J. Autio et al.   FEBS LETTERS

Intracellular location of the early steps of the isoprenoid biosynthetic pathway in the trypanosomatids Leishmania major and Trypanosoma brucei

(2008) Juana Carrero-Lérida et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Glucose-induced Remodeling of Intermediary and Energy Metabolism in ProcyclicTrypanosoma brucei

(2008) Virginie Coustou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-acetyl D-glucosamine stimulates growth in procyclic forms of Trypanosoma brucei by inducing a metabolic shift

(2008) C. E. EBIKEME et al.   PARASITOLOGY

A comprehensive analysis of Trypanosoma brucei mitochondrial proteome

(2008) Aswini K. Panigrahi et al.   PROTEOMICS