A speed–fidelity trade-off determines the mutation rate and virulence of an RNA virus

RNA Recombination Enhances Adaptability and Is Required for Virus Spread and Virulence

(2016) Yinghong Xiao et al.   Cell Host & Microbe

Measurements of Intrahost Viral Diversity Are Extremely Sensitive to Systematic Errors in Variant Calling

(2016) John T. McCrone et al.   JOURNAL OF VIROLOGY

The Mutational Robustness of Influenza A Virus

(2016) Elisa Visher et al.   PLoS Pathogens

Viral quasispecies

(2015) Raul Andino et al.   VIROLOGY

Sequence-Specific Fidelity Alterations Associated with West Nile Virus Attenuation in Mosquitoes

(2015) Greta A. Van Slyke et al.   PLoS Pathogens

Matters of Size: Genetic Bottlenecks in Virus Infection and Their Potential Impact on Evolution

(2015) Mark P. Zwart et al.   Annual Review of Virology

Influenza A Virus Transmission Bottlenecks Are Defined by Infection Route and Recipient Host

(2014) Andrew Varble et al.   Cell Host & Microbe

Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases

(2014) Grace Campagnola et al.   JOURNAL OF VIROLOGY

Generation and characterization of influenza A viruses with altered polymerase fidelity

(2014) Peter P. H. Cheung et al.   Nature Communications

Alphavirus Mutator Variants Present Host-Specific Defects and Attenuation in Mammalian and Insect Models

(2014) Kathryn Rozen-Gagnon et al.   PLoS Pathogens

Variation in RNA Virus Mutation Rates across Host Cells

(2014) Marine Combe et al.   PLoS Pathogens

Thinking Outside the Triangle: Replication Fidelity of the Largest RNA Viruses

(2014) Everett Clinton Smith et al.   Annual Review of Virology

Mutational and fitness landscapes of an RNA virus revealed through population sequencing

(2013) Ashley Acevedo et al.   NATURE

Codon Usage Determines the Mutational Robustness, Evolutionary Capacity, and Virulence of an RNA Virus

(2012) Adam S. Lauring et al.   Cell Host & Microbe

Coxsackievirus B3 mutator strains are attenuated in vivo

(2012) N. F. Gnadig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Speed, dissipation, and error in kinetic proofreading

(2012) Arvind Murugan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reliable detection of subclonal single-nucleotide variants in tumour cell populations

(2012) Moritz Gerstung et al.   Nature Communications

From Molecular Genetics to Phylodynamics: Evolutionary Relevance of Mutation Rates Across Viruses

(2012) Rafael Sanjuán   PLoS Pathogens

Arbovirus high fidelity variant loses fitness in mosquitoes and mice

(2011) L. L. Coffey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viral Mutation Rates

(2010) R. Sanjuan et al.   JOURNAL OF VIROLOGY

Mutational fitness effects in RNA and single-stranded DNA viruses: common patterns revealed by site-directed mutagenesis studies

(2010) R. Sanjuan   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Limited Trafficking of a Neurotropic Virus Through Inefficient Retrograde Axonal Transport and the Type I Interferon Response

(2010) Karen Z. Lancaster et al.   PLoS Pathogens

Fidelity Variants of RNA Dependent RNA Polymerases Uncover an Indirect, Mutagenic Activity of Amiloride Compounds

(2010) Laura I. Levi et al.   PLoS Pathogens

Infidelity of SARS-CoV Nsp14-Exonuclease Mutant Virus Replication Is Revealed by Complete Genome Sequencing

(2010) Lance D. Eckerle et al.   PLoS Pathogens

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Engineering attenuated virus vaccines by controlling replication fidelity

(2008) Marco Vignuzzi et al.   NATURE MEDICINE

Rates of evolutionary change in viruses: patterns and determinants

(2008) Siobain Duffy et al.   NATURE REVIEWS GENETICS

Pacing a small cage: mutation and RNA viruses

(2008) Robert Belshaw et al.   TRENDS IN ECOLOGY & EVOLUTION

Multiple Host Barriers Restrict Poliovirus Trafficking in Mice

(2008) Sharon K. Kuss et al.   PLoS Pathogens