The Mutational Robustness of Influenza A Virus

RNA Recombination Enhances Adaptability and Is Required for Virus Spread and Virulence

(2016) Yinghong Xiao et al.   Cell Host & Microbe

Expected Effect of Deleterious Mutations on Within-Host Adaptation of Pathogens

(2015) Judith M. Fonville   JOURNAL OF VIROLOGY

Effective Lethal Mutagenesis of Influenza Virus by Three Nucleoside Analogs

(2015) Matthew D. Pauly et al.   JOURNAL OF VIROLOGY

Site-Specific Amino Acid Preferences Are Mostly Conserved in Two Closely Related Protein Homologs

(2015) Michael B. Doud et al.   MOLECULAR BIOLOGY AND EVOLUTION

Global circulation patterns of seasonal influenza viruses vary with antigenic drift

(2015) Trevor Bedford et al.   NATURE

Extremely High Mutation Rate of HIV-1 In Vivo

(2015) José M. Cuevas et al.   PLOS BIOLOGY

Influenza Virus Reassortment Is Enhanced by Semi-infectious Particles but Can Be Suppressed by Defective Interfering Particles

(2015) Judith M. Fonville et al.   PLoS Pathogens

Intrahost Dynamics of Influenza Virus Reassortment

(2014) H. Tao et al.   JOURNAL OF VIROLOGY

An Experimentally Determined Evolutionary Model Dramatically Improves Phylogenetic Fit

(2014) Jesse D. Bloom   MOLECULAR BIOLOGY AND EVOLUTION

Epistatically Interacting Substitutions Are Enriched during Adaptive Protein Evolution

(2014) Lizhi Ian Gong et al.   PLoS Genetics

A Quantitative High-Resolution Genetic Profile Rapidly Identifies Sequence Determinants of Hepatitis C Viral Fitness and Drug Sensitivity

(2014) Hangfei Qi et al.   PLoS Pathogens

The inherent mutational tolerance and antigenic evolvability of influenza hemagglutinin

(2014) Bargavi Thyagarajan et al.   eLife

Congruent Evolution of Fitness and Genetic Robustness in Vesicular Stomatitis Virus

(2013) I. S. Novella et al.   JOURNAL OF VIROLOGY

Mutational and fitness landscapes of an RNA virus revealed through population sequencing

(2013) Ashley Acevedo et al.   NATURE

The role of mutational robustness in RNA virus evolution

(2013) Adam S. Lauring et al.   NATURE REVIEWS MICROBIOLOGY

Genome-wide mutagenesis of influenza virus reveals unique plasticity of the hemagglutinin and NS1 proteins

(2013) N. S. Heaton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influenza Virus Reassortment Occurs with High Frequency in the Absence of Segment Mismatch

(2013) Nicolle Marshall et al.   PLoS Pathogens

Coronaviruses Lacking Exoribonuclease Activity Are Susceptible to Lethal Mutagenesis: Evidence for Proofreading and Potential Therapeutics

(2013) Everett Clinton Smith et al.   PLoS Pathogens

An Overlapping Protein-Coding Region in Influenza A Virus Segment 3 Modulates the Host Response

(2012) B. W. Jagger et al.   SCIENCE

The Potential for Respiratory Droplet-Transmissible A/H5N1 Influenza Virus to Evolve in a Mammalian Host

(2012) C. A. Russell et al.   SCIENCE

Reliable detection of subclonal single-nucleotide variants in tumour cell populations

(2012) Moritz Gerstung et al.   Nature Communications

Mutational Robustness of an RNA Virus Influences Sensitivity to Lethal Mutagenesis

(2011) J. D. Graci et al.   JOURNAL OF VIROLOGY

The Fitness Effects of Synonymous Mutations in DNA and RNA Viruses

(2011) José M. Cuevas et al.   MOLECULAR BIOLOGY AND EVOLUTION

Why do RNA viruses recombine?

(2011) Etienne Simon-Loriere et al.   NATURE REVIEWS MICROBIOLOGY

Prevalence of Epistasis in the Evolution of Influenza A Surface Proteins

(2011) Sergey Kryazhimskiy et al.   PLoS Genetics

Distribution of Fitness Effects Caused by Single-Nucleotide Substitutions in Bacteriophage f1

(2010) J. B. Peris et al.   GENETICS

Viral Mutation Rates

(2010) R. Sanjuan et al.   JOURNAL OF VIROLOGY

Mutational fitness effects in RNA and single-stranded DNA viruses: common patterns revealed by site-directed mutagenesis studies

(2010) R. Sanjuan   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Permissive Secondary Mutations Enable the Evolution of Influenza Oseltamivir Resistance

(2010) J. D. Bloom et al.   SCIENCE

Structural Basis of Preexisting Immunity to the 2009 H1N1 Pandemic Influenza Virus

(2010) R. Xu et al.   SCIENCE

Does Mutational Robustness Inhibit Extinction by Lethal Mutagenesis in Viral Populations?

(2010) Eamon B. O'Dea et al.   PLoS Computational Biology

Point Mutation Rate of Bacteriophage  X174

(2009) J. M. Cuevas et al.   GENETICS

A genetic background with low mutational robustness is associated with increased adaptability to a novel host in an RNA virus

(2009) J. M. CUEVAS et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

Single-Reaction Genomic Amplification Accelerates Sequencing and Vaccine Production for Classical and Swine Origin Human Influenza A Viruses

(2009) B. Zhou et al.   JOURNAL OF VIROLOGY

Fitness and its role in evolutionary genetics

(2009) H. Allen Orr   NATURE REVIEWS GENETICS

Genetic Drift of HIV Populations in Culture

(2009) Yegor Voronin et al.   PLoS Genetics

The Fitness Effects of Random Mutations in Single-Stranded DNA and RNA Bacteriophages

(2009) Pilar Domingo-Calap et al.   PLoS Genetics

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Robustness promotes evolvability of thermotolerance in an RNA virus

(2008) Robert C McBride et al.   BMC EVOLUTIONARY BIOLOGY

The genomic and epidemiological dynamics of human influenza A virus

(2008) Andrew Rambaut et al.   NATURE

Pacing a small cage: mutation and RNA viruses

(2008) Robert Belshaw et al.   TRENDS IN ECOLOGY & EVOLUTION