Ligustrazine attenuates renal damage by inhibiting endoplasmic reticulum stress in diabetic nephropathy by inactivating MAPK pathways

Liuwei Dihuang pill treats diabetic nephropathy in rats by inhibiting of TGF-β/SMADS, MAPK, and NF-kB and upregulating expression of cytoglobin in renal tissues

(2017) Zhong Ju Xu et al.   MEDICINE

Resveratrol ameliorates diabetic nephropathy in rats through negative regulation of the p38 MAPK/TGF-β1 pathway

(2017) Yuan Qiao et al.   Experimental and Therapeutic Medicine

Resistin-Like Molecule Beta (RELM-β) Regulates Proliferation of Human Diabetic Nephropathy Mesangial Cells via Mitogen-Activated Protein Kinases (MAPK) Signaling Pathway

(2017) Yun-Qian Wang et al.   MEDICAL SCIENCE MONITOR

Ligustrazine alleviates acute pancreatitis by accelerating acinar cell apoptosis at early phase via the suppression of p38 and Erk MAPK pathways

(2016) Jianli Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

PPARδ Is Required for Exercise to Attenuate Endoplasmic Reticulum Stress and Endothelial Dysfunction in Diabetic Mice

(2016) Wai San Cheang et al.   DIABETES

Protective effects of Danggui Buxue Tang on renal function, renal glomerular mesangium and heparanase expression in rats with streptozotocin-induced diabetes mellitus

(2016) TAI-SHENG YE et al.   Experimental and Therapeutic Medicine

BAY 11-7082 ameliorates diabetic nephropathy by attenuating hyperglycemia-mediated oxidative stress and renal inflammation via NF-κB pathway

(2015) Sambasiva Rao Kolati et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Astragaloside IV attenuates proteinuria in streptozotocin-induced diabetic nephropathy via the inhibition of endoplasmic reticulum stress

(2015) Zeng Si Wang et al.   BMC Nephrology

RTN1 mediates progression of kidney disease by inducing ER stress

(2015) Ying Fan et al.   Nature Communications

Autophagy inhibition induces podocyte apoptosis by activating the pro-apoptotic pathway of endoplasmic reticulum stress

(2014) Li Fang et al.   EXPERIMENTAL CELL RESEARCH

A novel proteoglycan from Ganoderma lucidum fruiting bodies protects kidney function and ameliorates diabetic nephropathy via its antioxidant activity in C57BL/6 db/db mice

(2013) Deng Pan et al.   FOOD AND CHEMICAL TOXICOLOGY

KDOQI Clinical Practice Guideline for Diabetes and CKD: 2012 Update

(2012)   AMERICAN JOURNAL OF KIDNEY DISEASES

The Apoptosis Inhibitor ARC Alleviates the ER Stress Response to Promote β-Cell Survival

(2012) Wendy M. McKimpson et al.   DIABETES

Protective effect of herbomineral formulation (Dolabi) on early diabetic nephropathy in streptozotocin-induced diabetic rats

(2011) Mirza A. Baig et al.   Journal of Natural Medicines

Ligustrazine improves atherosclerosis in rat via attenuation of oxidative stress

(2011) Fengrong Jiang et al.   PHARMACEUTICAL BIOLOGY

Attenuation of diabetic nephropathy in diabetes rats induced by streptozotocin by regulating the endoplasmic reticulum stress inflammatory response

(2010) Wei Qi et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Prevention of Diabetic Kidney Disease: Negative Clinical Trials With Renin-Angiotensin System Inhibitors

(2009) Robert G. Nelson et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

The Protective Mechanism of Ligustrazine Against Renal Ischemia/Reperfusion Injury

(2009) Li Feng et al.   JOURNAL OF SURGICAL RESEARCH

Endoplasmic reticulum stress in proteinuric kidney disease

(2009) Andrey V. Cybulsky   KIDNEY INTERNATIONAL

Critical Role of the Stress Chaperone GRP78/BiP in Tumor Proliferation, Survival, and Tumor Angiogenesis in Transgene-Induced Mammary Tumor Development

(2008) D. Dong et al.   CANCER RESEARCH

How IRE1 Reacts to ER Stress

(2008) David Ron et al.   CELL

Proteinuria and Hyperglycemia Induce Endoplasmic Reticulum Stress

(2008) M. T. Lindenmeyer et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Role of Inflammatory Cytokines in Diabetic Nephropathy

(2008) J. F. Navarro-Gonzalez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY