标题
New highlights on the health-improving effects of sulforaphane
作者
关键词
-
出版物
Food & Function
Volume 9, Issue 5, Pages 2589-2606
出版商
Royal Society of Chemistry (RSC)
发表日期
2018-04-18
DOI
10.1039/c8fo00018b
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Dysregulation of NRF2 in Cancer: from Molecular Mechanisms to Therapeutic Opportunities
- (2018) Byung-Jin Jung et al. Biomolecules & Therapeutics
- Sulforaphane induces differential modulation of mitochondrial biogenesis and dynamics in normal cells and tumor cells
- (2017) Mario Negrette-Guzmán et al. FOOD AND CHEMICAL TOXICOLOGY
- Reactive oxygen species and cancer paradox: To promote or to suppress?
- (2017) Sehamuddin Galadari et al. FREE RADICAL BIOLOGY AND MEDICINE
- Effects of sulforaphane on neural stem cell proliferation and differentiation
- (2017) Zhenxian Han et al. GENESIS
- d,l-Sulforaphane Induces ROS-Dependent Apoptosis in Human Gliomablastoma Cells by Inactivating STAT3 Signaling Pathway
- (2017) Ziwei Miao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells
- (2017) Jianyun Zhu et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- The impact of cruciferous vegetable isothiocyanates on histone acetylation and histone phosphorylation in bladder cancer
- (2017) Besma Abbaoui et al. Journal of Proteomics
- Targeted proteome analysis with isotope-coded protein labels for monitoring the influence of dietary phytochemicals on the expression of cytoprotective proteins in primary human colon cells
- (2017) Christiane Östreicher et al. Journal of Proteomics
- The effects of NRF2 modulation on the initiation and progression of chemically and genetically induced lung cancer
- (2017) Shasha Tao et al. MOLECULAR CARCINOGENESIS
- Sulforaphane Protects against High Cholesterol-Induced Mitochondrial Bioenergetics Impairments, Inflammation, and Oxidative Stress and Preserves Pancreaticβ-Cells Function
- (2017) Catalina Carrasco-Pozo et al. Oxidative Medicine and Cellular Longevity
- Sulforaphane as an adjunctive to everolimus counteracts everolimus resistance in renal cancer cell lines
- (2017) Eva Juengel et al. PHYTOMEDICINE
- Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes
- (2017) Annika S. Axelsson et al. Science Translational Medicine
- Mitochondrial dysfunction in cancer chemoprevention by phytochemicals from dietary and medicinal plants
- (2017) Anuradha Sehrawat et al. SEMINARS IN CANCER BIOLOGY
- Sulforaphane-Induced Cell Cycle Arrest and Senescence are accompanied by DNA Hypomethylation and Changes in microRNA Profile in Breast Cancer Cells
- (2017) Anna Lewinska et al. Theranostics
- Sulforaphane Induced Apoptosis via Promotion of Mitochondrial Fusion and ERK1/2-Mediated 26S Proteasome Degradation of Novel Pro-survival Bim and Upregulation of Bax in Human Non-Small Cell Lung Cancer Cells
- (2017) Yang Geng et al. Journal of Cancer
- Sulforaphane is a Nrf2-independent inhibitor of mitochondrial fission
- (2017) Gary B. O'Mealey et al. Redox Biology
- Sulforaphane enhances irradiation effects in terms of perturbed cell cycle progression and increased DNA damage in pancreatic cancer cells
- (2017) Patrick Naumann et al. PLoS One
- Sulforaphane Induces Cell Death Through G2/M Phase Arrest and Triggers Apoptosis in HCT 116 Human Colon Cancer Cells
- (2016) Kuo-Ching Liu et al. AMERICAN JOURNAL OF CHINESE MEDICINE
- Development of a Novel Experimental In Vitro Model of Isothiocyanate-induced Apoptosis in Human Malignant Melanoma Cells
- (2016) THEODORA MANTSO et al. ANTICANCER RESEARCH
- Sulforaphane modulates telomerase activity via epigenetic regulation in prostate cancer cell lines
- (2016) Ata Abbas et al. Biochemistry and Cell Biology
- Sulforaphane suppresses in vitro and in vivo lung tumorigenesis through downregulation of HDAC activity
- (2016) Li-Li Jiang et al. BIOMEDICINE & PHARMACOTHERAPY
- Sulforaphane activates the cerebral vascular Nrf2–ARE pathway and suppresses inflammation to attenuate cerebral vasospasm in rat with subarachnoid hemorrhage
- (2016) Xudong Zhao et al. BRAIN RESEARCH
- Sulforaphane-induced apoptosis in human leukemia HL-60 cells through extrinsic and intrinsic signal pathways and altering associated genes expression assayed by cDNA microarray
- (2016) Hung-Sheng Shang et al. ENVIRONMENTAL TOXICOLOGY
- Sulforaphane prevents quinolinic acid-induced mitochondrial dysfunction in rat striatum
- (2016) Erika Rubí Luis-García et al. JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
- Sulforaphane Inhibits c-Myc-Mediated Prostate Cancer Stem-Like Traits
- (2016) Avani R. Vyas et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Activation of the nuclear factor E2-related factor 2/anitioxidant response element alleviates the nitroglycerin-induced hyperalgesia in rats
- (2016) Wei Di et al. JOURNAL OF HEADACHE AND PAIN
- Hyperammonemia induces glial activation, neuroinflammation and alters neurotransmitter receptors in hippocampus, impairing spatial learning: reversal by sulforaphane
- (2016) Vicente Hernández-Rabaza et al. Journal of Neuroinflammation
- Endoplasmic reticulum stress mediates sulforaphane-induced apoptosis of HepG2 human hepatocellular carcinoma cells
- (2016) Xiang Zou et al. Molecular Medicine Reports
- Sulforaphane exerts its anti-inflammatory effect against amyloid-β peptide via STAT-1 dephosphorylation and activation of Nrf2/HO-1 cascade in human THP-1 macrophages
- (2016) Ye Won An et al. NEUROBIOLOGY OF AGING
- Sulforaphane Regulates NFE2L2/Nrf2-Dependent Xenobiotic Metabolism Phase II and Phase III Enzymes Differently in Human Colorectal Cancer and Untransformed Epithelial Colon Cells
- (2016) Katarzyna Lubelska et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Sulforaphane inhibits TGF-β-induced epithelial-mesenchymal transition of hepatocellular carcinoma cells via the reactive oxygen species-dependent pathway
- (2016) JINSHENG WU et al. ONCOLOGY REPORTS
- Sulforaphane improves chemotherapy efficacy by targeting cancer stem cell-like properties via the miR-124/IL-6R/STAT3 axis
- (2016) Xingxing Wang et al. Scientific Reports
- Nrf2 sensitizes prostate cancer cells to radiation via decreasing basal ROS levels
- (2015) Min Liu et al. BIOFACTORS
- Nrf2 Activation Protects against Solar-Simulated Ultraviolet Radiation in Mice and Humans
- (2015) E. V. Knatko et al. Cancer Prevention Research
- Effect of Sulforaphane in Men with Biochemical Recurrence after Radical Prostatectomy
- (2015) B. G. Cipolla et al. Cancer Prevention Research
- Sensitization of estrogen receptor-positive breast cancer cell lines to 4-hydroxytamoxifen by isothiocyanates present in cruciferous plants
- (2015) Anna Pawlik et al. EUROPEAN JOURNAL OF NUTRITION
- Sulforaphane Reverses the Expression of Various Tumor Suppressor Genes by Targeting DNMT3B and HDAC1 in Human Cervical Cancer Cells
- (2015) Munawwar Ali Khan et al. Evidence-based Complementary and Alternative Medicine
- Metallothionein plays a prominent role in the prevention of diabetic nephropathy by sulforaphane via up-regulation of Nrf2
- (2015) Hao Wu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Sulforaphane exerts anti-inflammatory effects against lipopolysaccharide-induced acute lung injury in mice through the Nrf2/ARE pathway
- (2015) TIANJIE QI et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- The Role of Sulforaphane in Epigenetic Mechanisms, Including Interdependence between Histone Modification and DNA Methylation
- (2015) Agnieszka Kaufman-Szymczyk et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Sulforaphane inhibits hypoxia-induced HIF-1α and VEGF expression and migration of human colon cancer cells
- (2015) DONG HWAN KIM et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression
- (2015) FENGMING LAN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Sulforaphane Attenuates Muscle Inflammation in Dystrophin-deficientmdxMice via NF-E2-related Factor 2 (Nrf2)-mediated Inhibition of NF-κB Signaling Pathway
- (2015) Cheng-Cao Sun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sulforaphane is anticonvulsant and improves mitochondrial function
- (2015) Catalina Carrasco-Pozo et al. JOURNAL OF NEUROCHEMISTRY
- Sulforaphane induces ROS mediated induction of NKG2D ligands in human cancer cell lines and enhances susceptibility to NK cell mediated lysis
- (2015) Prayag J. Amin et al. LIFE SCIENCES
- Sulforaphane reduces lipopolysaccharide-induced proinflammatory markers in hippocampus and liver but does not improve sickness behavior
- (2015) Brigitte E. Townsend et al. NUTRITIONAL NEUROSCIENCE
- Simultaneous Targeting of Bladder Tumor Growth, Survival, and Epithelial-to-Mesenchymal Transition with a Novel Therapeutic Combination of Acetazolamide (AZ) and Sulforaphane (SFN)
- (2015) S S Islam et al. Targeted Oncology
- Sulforaphane, a cancer chemopreventive agent, induces pathways associated with membrane biosynthesis in response to tissue damage by aflatoxin B1
- (2015) Nirachara Techapiesancharoenkij et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon
- (2015) Praveen Rajendran et al. Clinical Epigenetics
- Inhibition of autophagy by 3-methyladenine potentiates sulforaphane-induced cell death of BE(2)-C human neuroblastoma cells
- (2015) IRENA HORWACIK et al. Molecular Medicine Reports
- Sulforaphane counteracts aggressiveness of pancreatic cancer driven by dysregulated Cx43-mediated gap junctional intercellular communication
- (2015) Tobias Forster et al. Oncotarget
- Sulforaphane induces apoptosis in T24 human urinary bladder cancer cells through a reactive oxygen species-mediated mitochondrial pathway: The involvement of endoplasmic reticulum stress and the Nrf2 signaling pathway
- (2014) GUK HEUI JO et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer
- (2014) Joshi J. Alumkal et al. INVESTIGATIONAL NEW DRUGS
- The Fas Death Signaling Pathway Connecting Reactive Oxygen Species Generation and FLICE Inhibitory Protein Down-Regulation
- (2014) L. Wang et al. JOURNAL OF IMMUNOLOGY
- Sulforaphane pretreatment prevents systemic inflammation and renal injury in response to cardiopulmonary bypass
- (2014) Bao Nguyen et al. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
- Modulation of apoptosis by sulforaphane is associated with PGC-1α stimulation and decreased oxidative stress in cardiac myoblasts
- (2014) Rafael O. Fernandes et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Angiotensin II regulates testicular peritubular cell function via AT1 receptor: A specific situation in male infertility
- (2014) H. Welter et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Control of antioxidative response by the tumor suppressor protein PML through regulating Nrf2 activity
- (2014) Shuang Guo et al. MOLECULAR BIOLOGY OF THE CELL
- Activation of Nrf2 Pathways Correlates with Resistance of NSCLC Cell Lines to CBP501 In Vitro
- (2014) N. Mine et al. MOLECULAR CANCER THERAPEUTICS
- Transcriptome analysis reveals a dynamic and differential transcriptional response to sulforaphane in normal and prostate cancer cells and suggests a role for Sp1 in chemoprevention
- (2014) Laura M. Beaver et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Sulforaphane suppresses cardiac hypertrophy by inhibiting GATA4/GATA6 expression and MAPK signaling pathways
- (2014) Hae Jin Kee et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Molecular targets of isothiocyanates in cancer: Recent advances
- (2014) Parul Gupta et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Interactions between drugs and sulforaphane modulate the drug metabolism enzymatic system
- (2014) Katarzyna Lubelska et al. Pharmacological Reports
- Sulforaphane Induces Oxidative Stress and Death by p53-Independent Mechanism: Implication of Impaired Glutathione Recycling
- (2014) José Miguel P. Ferreira de Oliveira et al. PLoS One
- Sulforaphane Protects Rodent Retinas against Ischemia-Reperfusion Injury through the Activation of the Nrf2/HO-1 Antioxidant Pathway
- (2014) Hong Pan et al. PLoS One
- Regulation of NF-κB by TNF family cytokines
- (2014) Matthew S. Hayden et al. SEMINARS IN IMMUNOLOGY
- Protection by sulforaphane from type 1 diabetes-induced testicular apoptosis is associated with the up-regulation of Nrf2 expression and function
- (2014) Xin Jiang et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Modulation of cisplatin sensitivity in human ovarian carcinoma A2780 and SKOV3 cell lines by sulforaphane
- (2014) Luba Hunakova et al. TOXICOLOGY LETTERS
- Effects of co-treatment with sulforaphane and autophagy modulators on uridine 5′-diphospho-glucuronosyltransferase 1A isoforms and cytochrome P450 3A4 expression in Caco-2 human colon cancer cells
- (2014) MIN WANG et al. Oncology Letters
- SUV39H1/H3K9me3 attenuates sulforaphane-induced apoptotic signaling in PC3 prostate cancer cells
- (2014) G W Watson et al. Oncogenesis
- Sulforaphane Accelerates Acetaldehyde Metabolism by Inducing Aldehyde Dehydrogenases: Relevance to Ethanol Intolerance
- (2013) Yusuke Ushida et al. ALCOHOL AND ALCOHOLISM
- Longitudinal study of [D10]phenanthrene metabolism by the diol epoxide pathway in smokers
- (2013) Stephen S. Hecht et al. BIOMARKERS
- Nrf2 modulates contractile and metabolic properties of skeletal muscle in streptozotocin-induced diabetic atrophy
- (2013) Samantha A Whitman et al. EXPERIMENTAL CELL RESEARCH
- Sulforaphane induces reactive oxygen species-mediated mitotic arrest and subsequent apoptosis in human bladder cancer 5637 cells
- (2013) Hyun Soo Park et al. FOOD AND CHEMICAL TOXICOLOGY
- Oncogenic functions of the transcription factor Nrf2
- (2013) Irene Gañán-Gómez et al. FREE RADICAL BIOLOGY AND MEDICINE
- Prevention by sulforaphane of diabetic cardiomyopathy is associated with up-regulation of Nrf2 expression and transcription activation
- (2013) Yang Bai et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Alterations of Histone H1 Phosphorylation During Bladder Carcinogenesis
- (2013) Kelly H. Telu et al. JOURNAL OF PROTEOME RESEARCH
- Sub-chronic sulforaphane exposure in CD-1 pregnant mice enhances maternal NADPH quinone oxidoreductase 1 (NQO1) activity and mRNA expression of NQO1, glutathione S-transferase, and glutamate-cysteine ligase: Potential implications for fetal protection against toxicant exposure
- (2013) Nicola A. Philbrook et al. REPRODUCTIVE TOXICOLOGY
- The aryl hydrocarbon receptor and estrogen receptor alpha differentially modulate nuclear factor erythroid-2-related factor 2 transactivation in MCF-7 breast cancer cells
- (2013) Raymond Lo et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial- and endoplasmic reticulum stress-dependent pathways in the mouse model
- (2013) Xin Jiang et al. TOXICOLOGY LETTERS
- Epigenetic regulation of the human telomerase reverse transciptase gene: A potential therapeutic target for the treatment of leukemia (Review)
- (2013) XINBING SUI et al. Oncology Letters
- Aflatoxin B1-induced hepatocellular carcinoma in developing countries: Geographical distribution, mechanism of action and prevention
- (2013) ABDU SELIM HAMID et al. Oncology Letters
- Chronic sulforaphane oral treatment accentuates blood glucose impairment and may affect GLUT3 expression in the cerebral cortex and hypothalamus of rats fed with a highly palatable diet
- (2013) C. G. Souza et al. Food & Function
- Hydrogen Sulfide Stimulates Ischemic Vascular Remodeling Through Nitric Oxide Synthase and Nitrite Reduction Activity Regulating Hypoxia‐Inducible Factor‐1α and Vascular Endothelial Growth Factor–Dependent Angiogenesis
- (2013) Shyamal C. Bir et al. Journal of the American Heart Association
- Mitochondrial superoxide mediates doxorubicin-induced keratinocyte apoptosis through oxidative modification of ERK and Bcl-2 ubiquitination
- (2012) Sudjit Luanpitpong et al. BIOCHEMICAL PHARMACOLOGY
- Impact of Thermal Processing on Sulforaphane Yield from Broccoli (Brassica oleracea L. ssp. italica)
- (2012) Grace C. Wang et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Neuroprotective Effects of Sulforaphane after Contusive Spinal Cord Injury
- (2012) Andrea L. Benedict et al. JOURNAL OF NEUROTRAUMA
- Induction of Phase 2 Antioxidant Enzymes by Broccoli Sulforaphane: Perspectives in Maintaining the Antioxidant Activity of Vitamins A, C, and E
- (2012) Sekhar Boddupalli et al. Frontiers in Genetics
- Novel Function of Transcription Factor Nrf2 as an Inhibitor of RON Tyrosine Kinase Receptor-mediated Cancer Cell Invasion
- (2011) Amalraj Thangasamy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Deacetylation and methylation at histone H3 lysine 9 (H3K9) coordinate chromosome condensation during cell cycle progression
- (2011) Jin-Ah Park et al. MOLECULES AND CELLS
- Sulforaphane-Mediated Reduction of Aflatoxin B1-N7-Guanine in Rat Liver DNA: Impacts of Strain and Sex
- (2011) Jeannette L. A. Fiala et al. TOXICOLOGICAL SCIENCES
- Protective effect of sulforaphane pretreatment against cisplatin-induced liver and mitochondrial oxidant damage in rats
- (2011) Leobardo Gaona-Gaona et al. TOXICOLOGY
- Targeting mitochondria for cancer therapy
- (2010) David M. Hockenbery ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Protective effect of sulforaphane against oxidative stress: Recent advances
- (2010) Carlos Enrique Guerrero-Beltrán et al. EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY
- DNMT1 Stability Is Regulated by Proteins Coordinating Deubiquitination and Acetylation-Driven Ubiquitination
- (2010) Z. Du et al. Science Signaling
- Glucoraphanin hydrolysis by microbiota in the rat cecum results in sulforaphane absorption
- (2010) Ren-Hau Lai et al. Food & Function
- Putative chemopreventive molecules can increase Nrf2-regulated cell defense in some human cancer cell lines, resulting in resistance to common cytotoxic therapies
- (2009) Liangao Hu et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Sulforaphane treatment protects skeletal muscle against damage induced by exhaustive exercise in rats
- (2009) Marco Malaguti et al. JOURNAL OF APPLIED PHYSIOLOGY
- PRMT5 is required for cell-cycle progression and p53 tumor suppressor function
- (2009) A. Scoumanne et al. NUCLEIC ACIDS RESEARCH
- Pharmacokinetics and Pharmacodynamics of Broccoli Sprouts on the Suppression of Prostate Cancer in Transgenic Adenocarcinoma of Mouse Prostate (TRAMP) Mice: Implication of Induction of Nrf2, HO-1 and Apoptosis and the Suppression of Akt-dependent Kinase Pathway
- (2009) Young-Sam Keum et al. PHARMACEUTICAL RESEARCH
- Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway
- (2008) Marc A. Riedl et al. CLINICAL IMMUNOLOGY
- Histone H1 and its isoforms: Contribution to chromatin structure and function
- (2008) Nicole Happel et al. GENE
- Effect of angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade on apoptotic changes in contralateral testis following unilateral testicular torsion
- (2008) Gokhan Gokce et al. INTERNATIONAL UROLOGY AND NEPHROLOGY
- The role of Nrf2 in increased reactive oxygen species and DNA damage in prostate tumorigenesis
- (2008) D A Frohlich et al. ONCOGENE
- Dual roles of Nrf2 in cancer
- (2008) A LAU et al. PHARMACOLOGICAL RESEARCH
- Nuclear factor-κB1: Regulation and function
- (2007) Silvia Gaspar Pereira et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started