Sulforaphane Attenuates Muscle Inflammation in Dystrophin-deficientmdxMice via NF-E2-related Factor 2 (Nrf2)-mediated Inhibition of NF-κB Signaling Pathway

Sulforaphane alleviates muscular dystrophy in mdx mice by activation of Nrf2

(2015) Chengcao Sun et al.   JOURNAL OF APPLIED PHYSIOLOGY

Nuclear Factor κB Inhibition Reduces Lung Vascular Lumen Obliteration in Severe Pulmonary Hypertension in Rats

(2014) Daniela Farkas et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Sulforaphane reduces vascular inflammation in mice and prevents TNF-α-induced monocyte adhesion to primary endothelial cells through interfering with the NF-κB pathway

(2014) Palanisamy Nallasamy et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Sulforaphane pretreatment prevents systemic inflammation and renal injury in response to cardiopulmonary bypass

(2014) Bao Nguyen et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Ongoing therapeutic trials and outcome measures for Duchenne muscular dystrophy

(2013) Alessandra Govoni et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects

(2013) Christopher R. Heier et al.   EMBO Molecular Medicine

Nuclear Factor κ-B Is Activated in the Pulmonary Vessels of Patients with End-Stage Idiopathic Pulmonary Arterial Hypertension

(2013) Laura C. Price et al.   PLoS One

Chronic sulforaphane oral treatment accentuates blood glucose impairment and may affect GLUT3 expression in the cerebral cortex and hypothalamus of rats fed with a highly palatable diet

(2013) C. G. Souza et al.   Food & Function

Metabolic Effects of Sulforaphane Oral Treatment in Streptozotocin-Diabetic Rats

(2012) Carolina Guerini de Souza et al.   JOURNAL OF MEDICINAL FOOD

Dietary phytochemicals and cancer prevention: Nrf2 signaling, epigenetics, and cell death mechanisms in blocking cancer initiation and progression

(2012) Jong Hun Lee et al.   PHARMACOLOGY & THERAPEUTICS

Long-Term Blocking of Calcium Channels in mdx Mice Results in Differential Effects on Heart and Skeletal Muscle

(2011) Louise H. Jørgensen et al.   AMERICAN JOURNAL OF PATHOLOGY

Deubiquitinating enzyme A20 negatively regulates NF-κB signaling in skeletal muscle in mdx mice

(2011) Rakshita A. Charan et al.   FASEB JOURNAL

Resveratrol Ameliorates Muscular Pathology in the Dystrophic mdx Mouse, a Model for Duchenne Muscular Dystrophy

(2011) Y. S. Hori et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells

(2010) Y. Li et al.   CLINICAL CANCER RESEARCH

Disruption of Nrf2 Enhances the Upregulation of Nuclear Factor-kappaB Activity, Tumor Necrosis Factor-α, and Matrix Metalloproteinase-9 after Spinal Cord Injury in Mice

(2010) Lei Mao et al.   MEDIATORS OF INFLAMMATION

Green tea extract decreases muscle pathology and NF-κB immunostaining in regenerating muscle fibers of mdx mice

(2009) Nicholas P. Evans et al.   CLINICAL NUTRITION

Contrasting effects of steroids and angiotensin-converting-enzyme inhibitors in a mouse model of dystrophin-deficient cardiomyopathy

(2009) Ralf Bauer et al.   EUROPEAN JOURNAL OF HEART FAILURE

Gene therapy for muscular dystrophy: current progress and future prospects

(2009) Capucine Trollet et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

The antimicrobial effects of glucosinolates and their respective enzymatic hydrolysis products on bacteria isolated from the human intestinal tract

(2009) A. Aires et al.   JOURNAL OF APPLIED MICROBIOLOGY

Therapeutic targeting of signaling pathways in muscular dystrophy

(2009) Shephali Bhatnagar et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Role of Nrf2 in Protection against Traumatic Brain Injury in Mice

(2009) Wei Jin et al.   JOURNAL OF NEUROTRAUMA

Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and pharmacological and psychosocial management

(2009) Katharine Bushby et al.   LANCET NEUROLOGY

Sulforaphane suppresses TNF-α-mediated activation of NF-κB and induces apoptosis through activation of reactive oxygen species-dependent caspase-3

(2008) Dong-Oh Moon et al.   CANCER LETTERS

Akt activation prevents the force drop induced by eccentric contractions in dystrophin-deficient skeletal muscle

(2008) Bert Blaauw et al.   HUMAN MOLECULAR GENETICS

Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy

(2008) S. A. Villalta et al.   HUMAN MOLECULAR GENETICS