d,l-Sulforaphane Induces ROS-Dependent Apoptosis in Human Gliomablastoma Cells by Inactivating STAT3 Signaling Pathway

Suppression of IL-8-Src signalling axis by 17β-estradiol inhibits human mesenchymal stem cells-mediated gastric cancer invasion

(2016) Chung-Jung Liu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

STAT3 in the systemic inflammation of cancer cachexia

(2016) Teresa A. Zimmers et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Sugiol inhibits STAT3 activity via regulation of transketolase and ROS-mediated ERK activation in DU145 prostate carcinoma cells

(2015) Seung-Nam Jung et al.   BIOCHEMICAL PHARMACOLOGY

Overcoming the blood–brain tumor barrier for effective glioblastoma treatment

(2015) O. van Tellingen et al.   DRUG RESISTANCE UPDATES

Glioblastoma multiforme: Pathogenesis and treatment

(2015) Constantinos Alifieris et al.   PHARMACOLOGY & THERAPEUTICS

6-Shogaol exerts anti-proliferative and pro-apoptotic effects through the modulation of STAT3 and MAPKs signaling pathways

(2015) Sung-Moo Kim et al.   MOLECULAR CARCINOGENESIS

STAT3 Tyr705 phosphorylation affects clinical outcome in patients with newly diagnosed supratentorial glioblastoma

(2014) Guo-Shi Lin et al.   MEDICAL ONCOLOGY

STAT3 Activation in Glioblastoma: Biochemical and Therapeutic Implications

(2014) Jennifer Kim et al.   Cancers

Transcription Factor STAT3 as a Novel Molecular Target for Cancer Prevention

(2014) Ailian Xiong et al.   Cancers

Sulforaphane protects against ethanol-induced oxidative stress and apoptosis in neural crest cells by the induction of Nrf2-mediated antioxidant response

(2013) X Chen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Functional relevance of d,l-sulforaphane-mediated induction of vimentin and plasminogen activator inhibitor-1 in human prostate cancer cells

(2013) Avani R. Vyas et al.   EUROPEAN JOURNAL OF NUTRITION

Modulation of mitochondrial functions by the indirect antioxidant sulforaphane: A seemingly contradictory dual role and an integrative hypothesis

(2013) Mario Negrette-Guzmán et al.   FREE RADICAL BIOLOGY AND MEDICINE

Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem Cells

(2012) Jian Chen et al.   CELL

Pharmacological Targeting of the Transcription Factor Nrf2 at the Basal Ganglia Provides Disease Modifying Therapy for Experimental Parkinsonism

(2011) Agnieszka Jazwa et al.   ANTIOXIDANTS & REDOX SIGNALING

Upsides and Downsides of Reactive Oxygen Species for Cancer: The Roles of Reactive Oxygen Species in Tumorigenesis, Prevention, and Therapy

(2011) Subash C. Gupta et al.   ANTIOXIDANTS & REDOX SIGNALING

D,L-sulforaphane-induced apoptosis in human breast cancer cells is regulated by the adapter protein p66Shc

(2011) Kozue Sakao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Therapeutic Potential of AZD1480 for the Treatment of Human Glioblastoma

(2011) B. C. McFarland et al.   MOLECULAR CANCER THERAPEUTICS

Role of Lipid Peroxidation in Cellular Responses tod,l-Sulforaphane, a Promising Cancer Chemopreventive Agent

(2010) Rajendra Sharma et al.   BIOCHEMISTRY

Sulforaphane Inhibits Constitutive and Interleukin-6-Induced Activation of Signal Transducer and Activator of Transcription 3 in Prostate Cancer Cells

(2010) E. R. Hahm et al.   Cancer Prevention Research

Sulforaphane Causes Epigenetic Repression of hTERT Expression in Human Breast Cancer Cell Lines

(2010) Syed M. Meeran et al.   PLoS One

Cancer Prevention With Natural Compounds

(2010) Norleena P. Gullett et al.   SEMINARS IN ONCOLOGY

STAT3 as a Central Regulator of Tumor Metastases

(2009) Eswaran Devarajan et al.   CURRENT MOLECULAR MEDICINE

Manumycin inhibits STAT3, telomerase activity, and growth of glioma cells by elevating intracellular reactive oxygen species generation

(2009) Deobrat Dixit et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cellular Responses to Cancer Chemopreventive Agent D,L-Sulforaphane in Human Prostate Cancer Cells Are Initiated by Mitochondrial Reactive Oxygen Species

(2009) Dong Xiao et al.   PHARMACEUTICAL RESEARCH

Reactive oxygen species: A double-edged sword in oncogenesis

(2009) Jin-Shui Pan et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE