标题
Dissecting the molecular pathophysiology of drug-induced liver injury
作者
关键词
-
出版物
WORLD JOURNAL OF GASTROENTEROLOGY
Volume 24, Issue 13, Pages 1373-1385
出版商
Baishideng Publishing Group Inc.
发表日期
2018-04-04
DOI
10.3748/wjg.v24.i13.1373
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- An Animal Model of Abacavir-Induced HLA-Mediated Liver Injury
- (2018) Binbin Song et al. TOXICOLOGICAL SCIENCES
- CSH guidelines for the diagnosis and treatment of drug-induced liver injury
- (2017) Yue-cheng Yu et al. Hepatology International
- Drug-Induced Liver Injury: Cascade of Events Leading to Cell Death, Apoptosis or Necrosis
- (2017) Andrea Iorga et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The transformation in biomarker detection and management of drug-induced liver injury
- (2017) Rachel J. Church et al. LIVER INTERNATIONAL
- Serum apolipoprotein A1 and haptoglobin, in patients with suspected drug-induced liver injury (DILI) as biomarkers of recovery
- (2017) Valentina Peta et al. PLoS One
- Omics-based identification of the combined effects of idiosyncratic drugs and inflammatory cytokines on the development of drug-induced liver injury
- (2017) J. Jiang et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury
- (2016) Francisco Javier Cubero et al. GASTROENTEROLOGY
- Removal of acetaminophen protein adducts by autophagy protects against acetaminophen-induced liver injury in mice
- (2016) Hong-Min Ni et al. JOURNAL OF HEPATOLOGY
- Disruption of BSEP Function in HepaRG Cells Alters Bile Acid Disposition and Is a Susceptive Factor to Drug-Induced Cholestatic Injury
- (2016) Xi Qiu et al. MOLECULAR PHARMACEUTICS
- Choose Delicately and Reuse Adequately: The Newly Revealed Process of Autophagy
- (2015) Satoru Kobayashi BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Phloretin ameliorates arsenic trioxide induced mitochondrial dysfunction in H9c2 cardiomyoblasts mediated via alterations in membrane permeability and ETC complexes
- (2015) Vadavanath Prabhakaran Vineetha et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- p62/SQSTM1 functions as a signaling hub and an autophagy adaptor
- (2015) Yoshinori Katsuragi et al. FEBS Journal
- Receptor interacting protein kinase 1 mediates murine acetaminophen toxicity independent of the necrosome and not through necroptosis
- (2015) Lily Dara et al. HEPATOLOGY
- The chemical, genetic and immunological basis of idiosyncratic drug–induced liver injury
- (2015) A Tailor et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- Evolving models of the immunopathogenesis of T cell–mediated drug allergy: The role of host, pathogens, and drug response
- (2015) Katie D. White et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Metabolic activation and drug-induced liver injury:in vitroapproaches for the safety risk assessment of new drugs
- (2015) M. José Gómez-Lechón et al. JOURNAL OF APPLIED TOXICOLOGY
- Chronic Deletion and Acute Knockdown of Parkin Have Differential Responses to Acetaminophen-induced Mitophagy and Liver Injury in Mice
- (2015) Jessica A. Williams et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cytotoxic Synergy Between Cytokines and NSAIDs Associated With Idiosyncratic Hepatotoxicity Is Driven by Mitogen-Activated Protein Kinases
- (2015) Ashley R. Maiuri et al. TOXICOLOGICAL SCIENCES
- Low Dose Acetaminophen Induces Reversible Mitochondrial Dysfunction Associated with Transient c-Jun N-Terminal Kinase Activation in Mouse Liver
- (2015) Jiangting Hu et al. TOXICOLOGICAL SCIENCES
- Inhibitor of apoptosis signal-regulating kinase 1 protects against acetaminophen-induced liver injury
- (2015) Yuchao Xie et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Time course of acetaminophen-protein adducts and acetaminophen metabolites in circulation of overdose patients and in HepaRG cells
- (2015) Yuchao Xie et al. XENOBIOTICA
- ACG Clinical Guideline: The Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury
- (2014) Naga P Chalasani et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Regulated Cell Death: Signaling and Mechanisms
- (2014) Avi Ashkenazi et al. Annual Review of Cell and Developmental Biology
- Autophagy revisited: A conversation with Christian de Duve
- (2014) Daniel J. Klionsky Autophagy
- Mitochondrial toxicity assessment in industry – a decade of technology development and insight
- (2014) Yvonne Will et al. Expert Opinion on Drug Metabolism & Toxicology
- Idiosyncratic Drug-Induced Liver Injury Is Associated With Substantial Morbidity and Mortality Within 6 Months From Onset
- (2014) Robert J. Fontana et al. GASTROENTEROLOGY
- Acetaminophen and NAPQI are toxic to auditory cells via oxidative and endoplasmic reticulum stress-dependent pathways
- (2014) Gilda M. Kalinec et al. HEARING RESEARCH
- The many functions of the endoplasmic reticulum chaperones and folding enzymes
- (2014) Laura Halperin et al. IUBMB LIFE
- Adiponectin protects against acetaminophen-induced mitochondrial dysfunction and acute liver injury by promoting autophagy in mice
- (2014) Zhuofeng Lin et al. JOURNAL OF HEPATOLOGY
- Regulated necrosis: the expanding network of non-apoptotic cell death pathways
- (2014) Tom Vanden Berghe et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Necroptosis
- (2014) Andreas Linkermann et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Plug Release Mechanism for Membrane Permeation by MLKL
- (2014) Lijing Su et al. STRUCTURE
- Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure
- (2014) Kenji Takemoto et al. FEBS Open Bio
- Momordin Ic induces HepG2 cell apoptosis through MAPK and PI3K/Akt-mediated mitochondrial pathways
- (2013) Jing Wang et al. APOPTOSIS
- Early detection of paracetamol toxicity using circulating liver microRNA and markers of cell necrosis
- (2013) James W. Dear et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Drug-induced Acute Liver Failure
- (2013) William M. Lee Clinics in Liver Disease
- Drug-Induced Liver Injury: Mechanisms, Types and Biomarkers
- (2013) M. Vinken et al. CURRENT MEDICINAL CHEMISTRY
- Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital
- (2013) Daniel J. Antoine et al. HEPATOLOGY
- Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen-induced hepatocyte necrosis in mice
- (2013) Anup Ramachandran et al. HEPATOLOGY
- CHOP is a critical regulator of acetaminophen-induced hepatotoxicity
- (2013) Dotan Uzi et al. JOURNAL OF HEPATOLOGY
- HLA Alleles Influence the Clinical Signature of Amoxicillin-Clavulanate Hepatotoxicity
- (2013) Camilla Stephens et al. PLoS One
- Plasma and liver acetaminophen-protein adduct levels in mice after acetaminophen treatment: Dose–response, mechanisms, and clinical implications
- (2013) Mitchell R. McGill et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice
- (2013) Jason Karch et al. eLife
- Role of immune reactions in drug-induced liver injury (DILI)
- (2012) Cynthia Ju et al. DRUG METABOLISM REVIEWS
- Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: Lessons learned from acetaminophen hepatotoxicity
- (2012) Hartmut Jaeschke et al. DRUG METABOLISM REVIEWS
- Sterile Inflammation in the Liver
- (2012) Paul Kubes et al. GASTROENTEROLOGY
- Increased susceptibility of natural killer T-cell-deficient mice to acetaminophen-induced liver injury
- (2012) Brittany V. Martin-Murphy et al. HEPATOLOGY
- The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation
- (2012) Mitchell R. McGill et al. JOURNAL OF CLINICAL INVESTIGATION
- Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity
- (2012) Daniel J. Antoine et al. JOURNAL OF HEPATOLOGY
- Role of Kupffer cells and toll-like receptor 4 in acetaminophen-induced acute liver failure
- (2012) James E. Fisher et al. JOURNAL OF SURGICAL RESEARCH
- Frequency of adverse drug reactions in hospitalized patients: a systematic review and meta-analysis
- (2012) Ana Miguel et al. PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
- Acetaminophen-induced liver injury in rats and mice: Comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity
- (2012) Mitchell R. McGill et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- In silico analysis of HLA associations with drug-induced liver injury: use of a HLA-genotyped DNA archive from healthy volunteers
- (2012) Ana Alfirevic et al. Genome Medicine
- CD95 death receptor and epidermal growth factor receptor (EGFR) in liver cell apoptosis and regeneration
- (2011) Roland Reinehr et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Many stimuli pull the necrotic trigger, an overview
- (2011) N Vanlangenakker et al. CELL DEATH AND DIFFERENTIATION
- Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles
- (2011) M. Isabel Lucena et al. GASTROENTEROLOGY
- c-Jun N-terminal Kinase (JNK)-dependent Acute Liver Injury from Acetaminophen or Tumor Necrosis Factor (TNF) Requires Mitochondrial Sab Protein Expression in Mice
- (2011) Sanda Win et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HLA-DQA1*02:01 Is a Major Risk Factor for Lapatinib-Induced Hepatotoxicity in Women With Advanced Breast Cancer
- (2011) Colin F. Spraggs et al. JOURNAL OF CLINICAL ONCOLOGY
- Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity
- (2011) Hartmut Jaeschke et al. LIVER INTERNATIONAL
- Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
- (2011) M. Cargnello et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Mechanisms of drug-induced liver injury: from bedside to bench
- (2011) Shannan Tujios et al. Nature Reviews Gastroenterology & Hepatology
- Microsomal oxidative damage promoted by acetaminophen metabolism
- (2011) María Eugenia Letelier et al. TOXICOLOGY IN VITRO
- Signaling cell death from the endoplasmic reticulum stress response
- (2010) Gordon C Shore et al. CURRENT OPINION IN CELL BIOLOGY
- The potential of cytokines as safety biomarkers for drug-induced liver injury
- (2010) Hugh G. Laverty et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Pathological aspects of lipid peroxidation
- (2010) Anne Negre-Salvayre et al. FREE RADICAL RESEARCH
- Cyclophilin D deficiency protects against acetaminophen-induced oxidant stress and liver injury
- (2010) Anup Ramachandran et al. FREE RADICAL RESEARCH
- A role for the pregnane X receptor in flucloxacillin-induced liver injury
- (2010) Elise Andrews et al. HEPATOLOGY
- Cytokine-associated drug toxicity in human hepatocytes is associated with signaling network dysregulation
- (2010) Benjamin D. Cosgrove et al. Molecular BioSystems
- Interference with Bile Salt Export Pump Function Is a Susceptibility Factor for Human Liver Injury in Drug Development
- (2010) Ryan E. Morgan et al. TOXICOLOGICAL SCIENCES
- c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity
- (2010) Chieko Saito et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation
- (2009) Rick D. Fannin et al. HEPATOLOGY
- HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin
- (2009) Ann K Daly et al. NATURE GENETICS
- Circulating microRNAs, potential biomarkers for drug-induced liver injury
- (2009) K. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epidemiology of Idiosyncratic Drug-Induced Liver Injury
- (2009) Lauren Bell et al. SEMINARS IN LIVER DISEASE
- High-Mobility Group Box-1 Protein and Keratin-18, Circulating Serum Proteins Informative of Acetaminophen-Induced Necrosis and Apoptosis In Vivo
- (2009) Daniel J. Antoine et al. TOXICOLOGICAL SCIENCES
- The role of damage associated molecular pattern molecules in acetaminophen-induced liver injury in mice
- (2009) Brittany V. Martin-Murphy et al. TOXICOLOGY LETTERS
- Deletion of Apoptosis Signal-Regulating Kinase 1 Attenuates Acetaminophen-Induced Liver Injury by Inhibiting c-Jun N-Terminal Kinase Activation
- (2008) Hayato Nakagawa et al. GASTROENTEROLOGY
- Mechanism of T cell tolerance induction by murine hepatic Kupffer cells
- (2008) Qiang You et al. HEPATOLOGY
- Innate immunity and acetaminophen-induced liver injury: Why so many controversies?
- (2008) Hartmut Jaeschke HEPATOLOGY
- Role of JNK Translocation to Mitochondria Leading to Inhibition of Mitochondria Bioenergetics in Acetaminophen-induced Liver Injury
- (2008) Naoko Hanawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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