SUMO2 and SUMO3 redundantly prevent a noncanonical type I interferon response

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A comprehensive compilation of SUMO proteomics

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Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi–Goutières Syndrome

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Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing

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SUMO2 is essential while SUMO3 is dispensable for mouse embryonic development

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PIAS1 negatively modulates virus triggered type I IFN signaling by blocking the DNA binding activity of IRF3

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Cytosolic Sensing of Viruses

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RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response

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IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling

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RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

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TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes

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