A comprehensive compilation of SUMO proteomics

Ubiquitin modifications

(2016) Kirby N Swatek et al.   CELL RESEARCH

c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4

(2015) Román González-Prieto et al.   CELL CYCLE

Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells

(2015) Sara Bursomanno et al.   DNA REPAIR

SUMOylation and PARylation cooperate to recruit and stabilize SLX4 at DNA damage sites

(2015) R. Gonzalez-Prieto et al.   EMBO REPORTS

Expanding the ubiquitin code through post-translational modification

(2015) L. Herhaus et al.   EMBO REPORTS

Mapping the SUMOylated landscape

(2015) Karolin Eifler et al.   FEBS Journal

Functional Proteomics Study Reveals SUMOylation of TFII-I is Involved in Liver Cancer Cell Proliferation

(2015) Jun Tu et al.   JOURNAL OF PROTEOME RESEARCH

Regulation of SUMO2 Target Proteins by the Proteasome in Human Cells Exposed to Replication Stress

(2015) Sara Bursomanno et al.   JOURNAL OF PROTEOME RESEARCH

System-wide Analysis of SUMOylation Dynamics in Response to Replication Stress Reveals Novel Small Ubiquitin-like Modified Target Proteins and Acceptor Lysines Relevant for Genome Stability

(2015) Zhenyu Xiao et al.   MOLECULAR & CELLULAR PROTEOMICS

A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly

(2015) Nathalie Eisenhardt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase

(2015) Laurent Cappadocia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy

(2015) Alban Ordureau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of SUMO-2/3-modified proteins associated with mitotic chromosomes

(2015) Caelin Cubeñas-Potts et al.   PROTEOMICS

Proteotoxic stress reprograms the chromatin landscape of SUMO modification

(2015) Anne Seifert et al.   Science Signaling

SUMOylation-Mediated Regulation of Cell Cycle Progression and Cancer

(2015) Karolin Eifler et al.   TRENDS IN BIOCHEMICAL SCIENCES

System-wide identification of wild-type SUMO-2 conjugation sites

(2015) Ivo A. Hendriks et al.   Nature Communications

A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly

(2015) Nathalie Eisenhardt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase

(2015) Laurent Cappadocia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage

(2015) Ivo A. Hendriks et al.   Cell Reports

Proteotoxic stress reprograms the chromatin landscape of SUMO modification

(2015) Anne Seifert et al.   Science Signaling

PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

(2014) Lesley A. Kane et al.   JOURNAL OF CELL BIOLOGY

Oxidative stress–induced assembly of PML nuclear bodies controls sumoylation of partner proteins

(2014) Umut Sahin et al.   JOURNAL OF CELL BIOLOGY

Proteomic Analysis of Ubiquitin-Like Posttranslational Modifications Induced by the Adenovirus E4-ORF3 Protein

(2014) Sook-Young Sohn et al.   JOURNAL OF VIROLOGY

Uncovering SUMOylation Dynamics during Cell-Cycle Progression Reveals FoxM1 as a Key Mitotic SUMO Target Protein

(2014) Joost Schimmel et al.   MOLECULAR CELL

A Cellular System that Degrades Misfolded Proteins and Protects against Neurodegeneration

(2014) Lili Guo et al.   MOLECULAR CELL

Uncovering global SUMOylation signaling networks in a site-specific manner

(2014) Ivo A Hendriks et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SUMOylation of Myc-Family Proteins

(2014) Arianna Sabò et al.   PLoS One

Comprehensive Identification of SUMO2/3 Targets and Their Dynamics during Mitosis

(2014) Julie Schou et al.   PLoS One

Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli

(2014) F. Impens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteome-Wide Identification of SUMO2 Modification Sites

(2014) T. Tammsalu et al.   Science Signaling

Large-scale analysis of lysine SUMOylation by SUMO remnant immunoaffinity profiling

(2014) Frédéric Lamoliatte et al.   Nature Communications

SUMOylation of Psmd1 Controls Adrm1 Interaction with the Proteasome

(2014) Hyunju Ryu et al.   Cell Reports

Sumoylation: A Regulatory Protein Modification in Health and Disease

(2013) Annette Flotho et al.   Annual Review of Biochemistry

Multivalent interactions of the SUMO-interaction motifs in RING finger protein 4 determine the specificity for chains of the SUMO

(2013) Kirstin Keusekotten et al.   BIOCHEMICAL JOURNAL

SUMO-targeted ubiquitin ligases

(2013) Annie M. Sriramachandran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The SUMO system: a master organizer of nuclear protein assemblies

(2013) Nithya Raman et al.   CHROMOSOMA

SUMOylation negatively modulates target gene occupancy of the KDM5B, a histone lysine demethylase

(2013) Murilo TD Bueno et al.   Epigenetics

Status of Large-scale Analysis of Post-translational Modifications by Mass Spectrometry

(2013) Jesper V. Olsen et al.   MOLECULAR & CELLULAR PROTEOMICS

Immunoaffinity Enrichment and Mass Spectrometry Analysis of Protein Methylation

(2013) Ailan Guo et al.   MOLECULAR & CELLULAR PROTEOMICS

Regulation of DNA Damage Responses by Ubiquitin and SUMO

(2013) Stephen P. Jackson et al.   MOLECULAR CELL

Detecting endogenous SUMO targets in mammalian cells and tissues

(2013) Janina Becker et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SUMO and Ischemic Tolerance

(2013) Yang-ja Lee et al.   NEUROMOLECULAR MEDICINE

SUMOylation inhibits FOXM1 activity and delays mitotic transition

(2013) S S Myatt et al.   ONCOGENE

Heat shock induces a massive but differential inactivation of SUMO-specific proteases

(2012) Manuel P. Pinto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Protein Group Modification and Synergy in the SUMO Pathway as Exemplified in DNA Repair

(2012) Ivan Psakhye et al.   CELL

RNF4 is required for DNA double-strand break repair in vivo

(2012) R Vyas et al.   CELL DEATH AND DIFFERENTIATION

SUMOylation of hnRNP-K is required for p53-mediated cell-cycle arrest in response to DNA damage

(2012) Seong Won Lee et al.   EMBO JOURNAL

Sumoylation of MDC1 is important for proper DNA damage response

(2012) Kuntian Luo et al.   EMBO JOURNAL

SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage

(2012) Y. Yin et al.   GENES & DEVELOPMENT

RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair

(2012) Y. Galanty et al.   GENES & DEVELOPMENT

DNA Damage-induced Heterogeneous Nuclear Ribonucleoprotein K SUMOylation Regulates p53 Transcriptional Activation

(2012) Federico Pelisch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Poly-Small Ubiquitin-like Modifier (PolySUMO)-binding Proteins Identified through a String Search

(2012) Huaiyu Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteomic Analyses Reveal Divergent Ubiquitylation Site Patterns in Murine Tissues

(2012) Sebastian A. Wagner et al.   MOLECULAR & CELLULAR PROTEOMICS

An Acetylation Switch Regulates SUMO-Dependent Protein Interaction Networks

(2012) Rebecca Ullmann et al.   MOLECULAR CELL

Function and regulation of SUMO proteases

(2012) Christopher M. Hickey et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RNF4-Dependent Hybrid SUMO-Ubiquitin Chains Are Signals for RAP80 and Thereby Mediate the Recruitment of BRCA1 to Sites of DNA Damage

(2012) C. M. Guzzo et al.   Science Signaling

Global Identification of Modular Cullin-RING Ligase Substrates

(2011) Michael J. Emanuele et al.   CELL

Nuclear organization in genome stability: SUMO connections

(2011) Shigeki Nagai et al.   CELL RESEARCH

A role for SUMO in nucleotide excision repair

(2011) Hannah R. Silver et al.   DNA REPAIR

The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complex

(2011) Elisabeth Finkbeiner et al.   EMBO JOURNAL

Purification and identification of endogenous polySUMO conjugates

(2011) Roland Bruderer et al.   EMBO REPORTS

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

(2011) Sebastian A. Wagner et al.   MOLECULAR & CELLULAR PROTEOMICS

Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome

(2011) Woong Kim et al.   MOLECULAR CELL

Oncogenic Ras abrogates MEK SUMOylation that suppresses the ERK pathway and cell transformation

(2011) Yuji Kubota et al.   NATURE CELL BIOLOGY

A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis

(2011) J. D. Kessler et al.   SCIENCE

Comparative Proteomic Analysis Identifies a Role for SUMO in Protein Quality Control

(2011) M. H. Tatham et al.   Science Signaling

SUMO chains: polymeric signals: Figure 1

(2010) Alfred C.O. Vertegaal   BIOCHEMICAL SOCIETY TRANSACTIONS

A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression

(2010) Edward L. Huttlin et al.   CELL

Mass Spectrometric Analysis of Lysine Ubiquitylation Reveals Promiscuity at Site Level

(2010) Jannie M. R. Danielsen et al.   MOLECULAR & CELLULAR PROTEOMICS

Arsenic-Induced SUMO-Dependent Recruitment of RNF4 into PML Nuclear Bodies

(2010) Marie-Claude Geoffroy et al.   MOLECULAR BIOLOGY OF THE CELL

Site-Specific Identification of SUMO-2 Targets in Cells Reveals an Inverted SUMOylation Motif and a Hydrophobic Cluster SUMOylation Motif

(2010) Ivan Matic et al.   MOLECULAR CELL

A Proteomic Screen for Nucleolar SUMO Targets Shows SUMOylation Modulates the Function of Nop5/Nop58

(2010) Belinda J. Westman et al.   MOLECULAR CELL

Decoding signalling networks by mass spectrometry-based proteomics

(2010) Chunaram Choudhary et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ubiquitin signalling in DNA replication and repair

(2010) Helle D. Ulrich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Role for Non-Covalent SUMO Interaction Motifs in Pc2/CBX4 E3 Activity

(2010) Jacqueline C. Merrill et al.   PLoS One

Quantitative Phosphoproteomics Reveals Widespread Full Phosphorylation Site Occupancy During Mitosis

(2010) J. V. Olsen et al.   Science Signaling

SUMOylation and deSUMOylation at a glance

(2009) Y. Wang et al.   JOURNAL OF CELL SCIENCE

Proteomics Analysis of Nucleolar SUMO-1 Target Proteins upon Proteasome Inhibition

(2009) Vittoria Matafora et al.   MOLECULAR & CELLULAR PROTEOMICS

Quality Control of a Transcriptional Regulator by SUMO-Targeted Degradation

(2009) Z. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

Mislocalized Activation of Oncogenic RTKs Switches Downstream Signaling Outcomes

(2009) Chunaram Choudhary et al.   MOLECULAR CELL

The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress

(2009) Joanna R. Morris et al.   NATURE

Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks

(2009) Yaron Galanty et al.   NATURE

Principles of ubiquitin and SUMO modifications in DNA repair

(2009) Steven Bergink et al.   NATURE

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

System-Wide Changes to SUMO Modifications in Response to Heat Shock

(2009) F. Golebiowski et al.   Science Signaling

SUMO Modification Regulates BLM and RAD51 Interaction at Damaged Replication Forks

(2009) Karen J. Ouyang et al.   PLOS BIOLOGY

Arsenic trioxide stimulates SUMO-2/3 modification leading to RNF4-dependent proteolytic targeting of PML

(2008) Stefan R. Weisshaar et al.   FEBS LETTERS

The Ubiquitin-Proteasome System Is a Key Component of the SUMO-2/3 Cycle

(2008) Joost Schimmel et al.   MOLECULAR & CELLULAR PROTEOMICS

SUMO-2/3 Modification and Binding Regulate the Association of CENP-E with Kinetochores and Progression through Mitosis

(2008) Xiang-Dong Zhang et al.   MOLECULAR CELL

Identification of SUMO-Dependent Chromatin-Associated Transcriptional Repression Components by a Genome-wide RNAi Screen

(2008) Bastian Stielow et al.   MOLECULAR CELL

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY

A SIM-ultaneous role for SUMO and ubiquitin

(2008) J. Jefferson P. Perry et al.   TRENDS IN BIOCHEMICAL SCIENCES